Preview

Russian Journal of Transplantology and Artificial Organs

Advanced search

LAPAROSCOPIC LEFT LATERAL SECTIONECTOMY IN LIVING LIVER DONOR

https://doi.org/10.15825/1995-1191-2016-4-43-55

Abstract

Introduction. Living donor liver transplantation has proved to be an effective, safe and radical treatment modality for patients with end-stage liver diseases. Left lateral section (LLS) of donor’s liver is used in pediatric recipients. Laparoscopic LLS procurement was fi rst described by D. Cherqui in 2002. At present, this technique is routinely used only by 5 hospitals in the world. However, up to date, some authors consider it to be a new standard to perform such a surgery in living donors.

Aim. To analyze the fi rst Russian experience in laparoscopic left lateral sectionectomy (LapLLS) in living related donor.

Materials and methods. From May to September 2016 fi ve LapLLS were performed in living donors. In all cases donors were women (mothers in 4 cases and aunt in 1 case). Recipients were children aged from 6 months through 3 years with body mass from 5.6 to 12.5 kg. Liver transection was carried out under conditions of maintained blood supply. Parenchymal transection was performed using a harmonic scalpel, bipolar coagulation and ultrasound dissection.

Results. Average donor age was 32 ± 5 years. Average operation time was 287 ± 16 min. Average LLS graft weight was 220 ± 16 g. Intraoperative blood loss did not exceed 100 ml (95 ± 5 ml). Donors were discharged on the 3rd–4th post-op day. There were no postoperative complications in donors. Recipients were also characterized by a standard course of the postoperative period.

Conclusion. LapLLS is an effective and safe method with several advantages. Primarily, these are early rehabilitation of the donors and shortening of the hospital stay, which are important for the quick return to normal way of live. Excellent visualization of anatomical structures, including vascular and biliary ones, allows performing precise selection. In addition, good cosmetic effect is also an important aspect.

About the Authors

S. V. Gautier
V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation I.M. Sechenov First Moscow State Medical University
Russian Federation
Moscow, Russian Federation


E. A. Gallyamov
A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Russian Federation
Moscow, Russian Federation


A. R. Monakhov
V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation I.M. Sechenov First Moscow State Medical University
Russian Federation
Moscow, Russian Federation


E. V. Zagainov
A.I. Yevdokimov Moscow State University of Medicine and Dentistry
Russian Federation
Moscow, Russian Federation


References

1. Готье CВ. Трансплантация печени: Руководство для врачей / Готье CВ, Константинов БА, Цирульникова ОМ. М.: Мед. информационное агентство, 2008. Gautier CV. Transplantaciya pecheni: Rukovodstvo dlya vrachej / Gautier CV, Konstantinov BA, Tsiroul’nikova OM. M.: Med. informacionnoe agentstvo, 2008.

2. Готье СВ и др. Клинические аспекты получения фрагментов печени от живых родственных доноров. Бюллетень сибирской медицины. 2007; 1. Gautier CV et al. Klinicheskie aspekty polucheniya fragmentov pecheni ot zhivyh rodstvennyh donorov. Byulleten’ sibirskoj mediciny. 2007; 1.

3. Константинов БА, Готье СВ. Трансплантация печени в России: проблемы, перспективы ближайшего десятилетия. Анн. хир. гепатол. 1998; 3. Konstantinov BA, Gautier SV. Transplantaciya pecheni v Rossii: problemy, perspektivy blizhajshego desyatiletiya. Ann. hir. gepatol. 1998; 3.

4. Готье СВ. Трансплантация печени детям: анализ шестилетнего опыта / Готье СВ, Ахаладзе ДГ. Вестник трансплантологии и искусственных органов. 2014; 16. Gautier SV. Transplantaciya pecheni detyam: analiz shestiletnego opyta / Gautier SV, Ahaladze DG. Vestnik transplantologii i iskusstvennyh organov. 2014; 16.

5. Kleemann M, Deichmann S, Esnaashari H. Laparoscopic Navigated Liver Resection: Technical Aspects and Clinical Practice in Benign Liver Tumors. Case Rep. Surg. 2012. doi: 10.1155/2012/265918.

6. Reddy SK, Tsung A, Geller DA. Laparoscopic liver resection. World J. Surg. 2011. doi: 10.1007/s00268-010-0906-5.

7. Cherqui D, Soubrane O, Husson E, Barshasz E, Vignaux O, Ghimouz M et al. Laparoscopic living donor hepatectomy for liver transplantation in children. Lancet. 2002; 359: 392–396.

8. Lin NC, Nitta H, Wakabayashi G. Laparoscopic major hepatectomy: a systematic literature review and comparison of 3 techniques. Ann. Surg. 2013; 257: 205–213. doi: 10.1097/SLA.0b013e31827da7fe.

9. Soubrane O, Cherqui D, Scatton O, Stenard F, Bernard D, Branchereau S et al. Laparoscopic left lateral sectionectomy in living donors: safety and reproducibility of the technique in a single center. Ann. Surg. 2006; 244: 815– 820.

10. Kim KH, Jung DH, Park KM, Lee YJ, Kim DY, Kim KM et al. Comparison of open and laparoscopic live donor left lateral sectionectomy. Br. J. Surg. 2011; 98: 1302–1308. doi: 10.1002/bjs.7601.

11. Koffron AJ, Kung R, Baker T, Fryer J, Clark L, Abecassis M. Laparoscopic- assisted right lobe donor hepatectomy. Am. J. Transplant. 2006; 6: 2522–2525.

12. Baker TB, Jay CL, Ladner DP, Preczewski LB, Clark L, Holl J et al. Laparoscopy- assisted and open living donor right hepatectomy: a comparative study of outcomes. Surgery. 2009; 146: 817–23; discussion 823-5. doi: 10.1016/j.surg.2009.05.022.

13. Eguchi S. et al. Elective living donor liver transplantation by hybrid handassisted laparoscopic surgery and short upper midline laparotomy. Surgery. 2011; 150 (5): 1002–1005.

14. Song GW, Lee SG. Living donor liver transplantation. Current opinion in organ transplantation. 2014; 19.

15. Giulianotti PC et al. Robot-assisted right lobe donor hepatectomy. Transplant. International. 2012; 25 (1): e5–e9.

16. Samstein B, Cherqui D, Rotellar F. Totally Laparoscopic Full Left Hepatectomy for Living Donor Liver Transplantation in Adolescents and Adults. American Journal of Transplantation. 2013; 13: 2462–2466.

17. Soubrane O, Perdigao Cotta F, Scatton O. Pure Laparoscopic Right Hepatectomy in a Living Donor. American Journal of Transplantation. 2013; 13: 2467–2471. Wiley Periodicals Inc.

18. Cauchy F, Schwarz L, Scatton O, Soubrane O. Laparoscopic liver resection for living donation: Where do we stand? World J. Gastroenterol. 2014 Nov 14; 20 (42): 15590–15598. PMCID: PMC4229523.

19. Wakabayashi G, Nitta H, Takahara T. Standardization of basic skills for laparoscopic liver surgery towards laparoscopic donor hepatectomy. Journal of Hepato-Biliary-Pancreatic Surgery. 2009 July; 16, Issue 4: 439–444.

20. Монахов АР. Прижизненное донорство фрагментов печени для трансплантации детям: дис. ... канд. мед. наук. М., 2015: 156. Monahov AR. Prizhiznennoe donorstvo fragmentov pecheni dlya transplantacii detyam: dis. ... kand. med. nauk. M., 2015: 156.

21. Готье СВ, Монахов АР. Обследование, отбор и подготовка прижизненных доноров фрагмента печени для трансплантации детям. Вестник трансплантологии и искусственных органов. 2015. 17 (1): 134–146. Gautier SV, Monakhov AR. Evaluation, selection and preparation of living donor for partial liver transplantation in children Vestnik transplantologii i iskusstvennykh organov. 2015. 17 (1): 134–146. doi: 10.15825/1995-1191-2015-1-134-146.

22. Dindo D, Demartines N, Clavien PA. Classification of Surgical Complications. Ann. Surg. 2004 Aug; 240 (2):205–213. doi: 10.1097/01.sla.0000133083.54934.ae.

23. Greco F et al. Laparoscopic living-donor nephrectomy: analysis of the existing literature. European urology. 2010; 58 (4): 498–509.

24. Готье СВ, Луцевич ОЭ, Мойсюк ЯГ, Галлямов ЭА, Панченков ДН, Ефимкин АС и др. Лапароскопическая мануально-ассистированная донорская нефрэктомия. Первый российский опыт. Вестник трансплантологии и искусственных органов. 2010; 12 (1):56–60. Gautier SV, Lutsevich OE, Moysyuk YG, Gallyamov EA, Panchenkov DN, Efi mkin AS. et al. Hand-assisted laparoscopic donor nephrectomy. The fi rst Russian experience. Vestnik transplantologii i iskusstvennykh organov. 2010; 12 (1): 56–60. doi: 10.15825/1995-1191-2010-1-56-60.


Review

For citations:


Gautier S.V., Gallyamov E.A., Monakhov A.R., Zagainov E.V. LAPAROSCOPIC LEFT LATERAL SECTIONECTOMY IN LIVING LIVER DONOR. Russian Journal of Transplantology and Artificial Organs. 2016;18(4):43-55. (In Russ.) https://doi.org/10.15825/1995-1191-2016-4-43-55

Views: 1911


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1995-1191 (Print)