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GATED SPECT IN PATIENTS WITH BIOPSY-NEGATIVE CARDIAC TRANSPLANT REJECTION

https://doi.org/10.15825/1995-1191-2009-3-62-68

Abstract

Humoral rejection of the cardiac allograft is still a challenging problem associated with high incidence of graft loss and patient mortality. These episodes of rejection are often more severe, and more difficult to treat, than classical acute cellular rejection. Hemodynamic compromise, in the absence of acute cellular rejection, called biopsy-negative rejection occurs in 10 to 20% of cardiac allograft recipients. The assessment of hemodynamic compromise can provide functional data in transplant patients that is complementary to myocardial biopsies if the biopsy can miss significant rejection. We present three cases of the biopsy-negative rejection. All patients have studied with gated SPECT phase analysis. 

About the Authors

E. N. Ostroumov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


V. M. Zakharevich
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


E. D. Kotina
Saint-Petersburg State University, Saint-Petersburg
Russian Federation


N. N. Mojeiko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


A. G. Kupriyanova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


E. I. Ryaboshtanova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


B. N. Morozov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


N. Z. Meboniya
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


S. V. Mironov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


A. Y. Kormer
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


I. M. Ilynsky
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


L. V. Beletskaya
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


E. N. Kazakov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


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For citations:


Ostroumov E.N., Zakharevich V.M., Kotina E.D., Mojeiko N.N., Kupriyanova A.G., Ryaboshtanova E.I., Morozov B.N., Meboniya N.Z., Mironov S.V., Kormer A.Y., Ilynsky I.M., Beletskaya L.V., Kazakov E.N. GATED SPECT IN PATIENTS WITH BIOPSY-NEGATIVE CARDIAC TRANSPLANT REJECTION. Russian Journal of Transplantology and Artificial Organs. 2009;11(3):62-68. (In Russ.) https://doi.org/10.15825/1995-1191-2009-3-62-68

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ISSN 1995-1191 (Print)