ПОЛИМЕРНЫЕ ПРОТЕЗЫ КЛАПАНОВ СЕРДЦА: СОСТОЯНИЕ И ПЕРСПЕКТИВЫ
https://doi.org/10.15825/1995-1191-2018-2-100-111
Аннотация
Идея создания полимерного клапана сердца, обладающего высокой прочностью и биосовместимостью, берет свое начало в 60-х годах. С тех пор исследовано множество полимерных соединений, однако так и не было найдено решение данной проблемы. В последние годы в связи с развитием технологий синтеза высокомолекулярных соединений появились новые полимеры, обладающие потенциалом для решения данной проблемы, о чем свидетельствует ряд публикаций, описывающих экспериментальные и клинические данные. Тем не менее поиск полимера для основы створчатого аппарата протеза клапана сердца не теряет своей актуальности ввиду изученных недостатков и отсутствия доказательной базы, подтверждающей долгосрочную безопасность таких изделий. В настоящем обзоре представлены первые результаты исследования полимерных протезов клапанов сердца на основе нанокомпозитного полимера из полиэдрических олигомерных силсесквиоксановых наночастиц и поликарбонатномочевинного уретанового полимера POSS-PCU, поли(стирол-блок-изобутилен-блок-стирола) – SIBS, политетрафторэтилена PTFE и др., возможность получения новых сополимеров и композитов на базе полимеров олефинового ряда и полиэстеров, продемонстрирована идея создания материала с заданной трехмерной микроархитектурой, определяющей анизотропию и необходимые механические свойства.
Об авторах
М. А. Резвова
ФГБНУ «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний».
Россия
650002, Кемерово, Сосновый бульвар, 6.
Россия
650002, Кемерово, Сосновый бульвар, 6.
Е. А. Овчаренко
ФГБНУ «Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний».
Россия
Россия
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Рецензия
Для цитирования:
Резвова М.А., Овчаренко Е.А. ПОЛИМЕРНЫЕ ПРОТЕЗЫ КЛАПАНОВ СЕРДЦА: СОСТОЯНИЕ И ПЕРСПЕКТИВЫ. Вестник трансплантологии и искусственных органов. 2018;20(2):100-111. https://doi.org/10.15825/1995-1191-2018-2-100-111
For citation:
Rezvova M.A., Ovcharenko E.A. POLYMERIC HEART VALVE PROSTHESES: CONDITION AND PERSPECTIVES. Russian Journal of Transplantology and Artificial Organs. 2018;20(2):100-111. (In Russ.) https://doi.org/10.15825/1995-1191-2018-2-100-111
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