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SPECIAL ASPECTS OF IMPLANTATION OF A HEART PUMP SUPPORT SYSTEM AVK-N AS A «BRIDGE» TO HEART TRANSPLANTATION

https://doi.org/10.15825/1995-1191-2018-1-13-22

Abstract

Aim: to develop an optimal surgical tactic for implantation of “AVK-N” system as a “bridge” to heart transplantation.

Materials and methods. 17 patients were included. They were operated in the period from 2012 to October 2017 in Federal State Budgetary Institution «V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs». A tiny implantable system «Portable device for assisting cardiac circulation» (AVK-N; Russia) was used for replacing the pumping function of the left ventricle. All patients were examined according to the program of potential recipients for heart transplantation, before the applying of prolonged mechanical circulatory support. Among the operated patients there were 16 (94.1%) men and 1 (5.9%) woman, the average age was 52.64 ± 10.56 (from 33 to 67 years). All patients had congestive heart failure III–IV functional class according to NYHA, refractory to optimal drug therapy. Heart failure was triggered by dilated cardiomyopathy in 12 (70,58%) cases, and by postinfarction systolic dysfunction of the left ventricle in 5 (29,42%). Implantation of «AVK-N» system was performed to potential recipients of the donor heart with terminal stage of CHF with a decrease in LV ejection fraction up to 10%.

Results. As a result of this study there were developed several technological aspects facilitating the subsequent heart transplantation.

Conclusion. Our experience in optimizing the surgical tactics of the “AVK-N” system implantation as a bridge to heart transplantation, demonstrated the possibility and safety of its active use in both patients with terminal heart failure on the waiting list of heart transplantation and patients having temporary contraindications to HTX.

About the Authors

T. A. Khalilulin
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation; I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenovsky University)
Russian Federation

Khalilulin Timur Abdulnaimovich

1, Shchukinskaya st., Moscow, 123182


V. M. Zacharevich
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation; I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenovsky University)
Russian Federation
Moscow


V. N. Poptsov
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


G. P. Itkin
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation; Moscow Institute of Physics and Technology (State University)
Russian Federation

Department of physics of living systems

Moscow


A. O. Shevchenko
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation; I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenovsky University)
Russian Federation

Department of cardiology N.I.Pirogov First Moscow State Medical University

Moscow


R. Sh. Saitgareev
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


A. M. Goltz
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


A. R. Zakiryanov
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


N. N. Koloskova
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


N. N. Abramova
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


N. Y. Zacharevich
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


E. A. Nikitina
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


M. A. Danilina
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


S. V. Gautier
V.I. Shumakov National Medical Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation; I.M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenovsky University)
Russian Federation
Moscow


References

1. Nacional’nye rekomendacii OSSN, RKO i RNMOT po diagnostike i lecheniyu HSN (chetvertyj peresmotr). Serdechnaya nedostatochnost’. 2013; 14; 7 (81): 379–472.

2. . Mareev VYU, Danielyan MO, Belenkov YUN. Ot imeni rabochej gruppy issledovaniya EHPOHA-OHSN. Sravnitel’naya harakteristika bol’nyh s HSN v zavisimosti ot velichiny FV po rezul’tatam Rossijskogo mnogo centrovogo issledovaniya EHPOHA-O-HSN. Serdechnaya nedostatochnost’. 2006; 7 (4): 164–171.

3. Kormos RL, Miller LW et al. Mechanical Circulatory Support – Elsevier. 2012; 367.

4. Holman WL, Kormos RL, Kirklin JK. Predictors of death and transplant in patients with a mechanical circulatory support device: a multi-institutional study. Heart. Lung. Transplant. 2009; 28: 44–50.

5. Itkin GP, Volkova EA. Razrabotka metodiki ehksperimental’noj i klinicheskoj aprobacii implantiruemyh osevyh nasosov. Transplantologiya: itogi i perspektivy. Pod red. S.V. Gautier. Tom V. 2013 god. M.–Tver’: Triada, 2014: 170–179.

6. Kirklin JK et al. Eighth annual INTERMACS report: Special focus on framing the impact of adverse events. Journal of Heart and Lung Transplantation. 2017; 36: 1080–1086.

7. Itkin GP, Konysheva EG, Shemakin SYu, Dozorov KN, Kudinov VL, Bykov IV, Selishchev SV. Teoreticheskoe i ehksperimental’noe rassmotrenie dinamicheskih harakteristik osevyh nasosov krovi. Vestnik transplantologii i iskusstvennyh organov. 2011; 13 (4): 91–96.

8. Itkin GP, Shohina EG, Shemakin SYu, Popcov VN, Shumakov DV, Gautier SV. Osobennosti dlitel’noj mekhanicheskoj podderzhki krovoobrashcheniya s pomoshch’yu nasosov nepreryvnogo potoka. Vestnik transplantologii i iskusstvennyh organov. 2012; 14 (2): 110–115.

9. Gautier SV, Itkin GP, Shevchenko AO, Halilulin TA, Kozlov VA. Dlitel’naya mekhanicheskaya podderzhka krovoobrashcheniya kak al’ternativa transplantacii serdca. Vestnik transplantologii i iskusstvennyh organov. 2016; 18 (3): 128–136.

10. Gautier SV, Kuleshov AP, Efi mov AE, Agapov II, Itkin GP. Optimizaciya implantiruemogo osevogo nasosa dlya povysheniya ehffektivnosti mekhanicheskoj podderzhki krovoobrashcheniya. Vestnik transplantologii i iskusstvennyh organov. 2017; 19 (2): 61–68.


Review

For citations:

Khalilulin T.A., Zacharevich V.M., Poptsov V.N., Itkin G.P., Shevchenko A.O., Saitgareev R.Sh., Goltz A.M., Zakiryanov A.R., Koloskova N.N., Abramova N.N., Zacharevich N.Y., Nikitina E.A., Danilina M.A., Gautier S.V. SPECIAL ASPECTS OF IMPLANTATION OF A HEART PUMP SUPPORT SYSTEM AVK-N AS A «BRIDGE» TO HEART TRANSPLANTATION. Russian Journal of Transplantology and Artificial Organs. 2018;20(1):13-22. https://doi.org/10.15825/1995-1191-2018-1-13-22

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ISSN 1995-1191 (Print)

"Academician V.I.Shumakov National Medical Research
Center of Transplantology and Artificial Organs",
Ministry of Health of the Russian Federation
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