VASCULAR COMPLICATIONS AFTER KIDNEY TRANSPLANTATION
https://doi.org/10.15825/1995-1191-2013-4-31-39
Abstract
Aim: evaluation of the incidence and the pattern of vessel complications, efficacy of the prophylactic anticoagulation therapy after kidney transplantation.
Materials and methods. From March 2007 till January 2013 421 patients: 230 men (54,6%) and 191 women (45,4%); mean age 43,07 ± 11,62 undergone 429 kidney transplantations in the department of pancreas and kidney transplantation of the Scientific-Research Institute of Emergency Care named after N.V. Sklifosovsky. In order to evaluate the condition and the function of the kidney transplant ultrasound investigation (daily) andacquisition(weekly) wereused. In cases of kidney dysfunction and assumption of vessel complications we used computerized tomography. Besides, we used daily analysis of biochemical and clinical parameters of blood and urine.
Results. The most common vessel complication was the thrombosis of the microvasculature of the kidney transplant due to acute humoral and combined rejection resistant to antirejection therapy (n = 9; 2,1%); in 4 cases there was a breakage of the transplant due to the acute rejection and the urgent transplantatectomy in an effort to save the patient; thrombosis of the transplantat artery occurred in 1 case (0,23%); we observed 2 cases (0,46%) of the artery stenosis and 2 cases (0,46%) of venous thrombosis.
Conclusion. Summary frequency of vessel complications in our clinic, including thrombosis due to rejection, was 3,49%. It fully corresponds with data obtained from the global medical community. The incidence of great vessel thrombosis was less than 1% which indicates the adequate prophylactic anticoagulation therapy. For the benefit of early diacrisis of complications Doppler sonography is needed. In case of assumption of vessel complications urgent acquisition, computerized tomography and/ or angiography are to be held.
About the Authors
M. Sh. Khubutia
State-financed health institution Scientific Research Institute of Emergency Care named after
N.V. Sklifosovsky, Moscow City Health care Department (Head – corresponding member of RAMSci, prof. M.Sh. Khubutia), Moscow, Russian Federation
A. V. Pinchuk
Department of kidney and pancreas transplantation (Head – cand. of med. sci. A.V. Pinchuk) at the same institute
N. V. Shmarina
Department of kidney and pancreas transplantation (Head – cand. of med. sci. A.V. Pinchuk) at the same institute
I. V. Dmitriev
Department of kidney and pancreas transplantation (Head – cand. of med. sci. A.V. Pinchuk) at the same institute
R. V. Storozhev
Department of kidney and pancreas transplantation (Head – cand. of med. sci. A.V. Pinchuk) at the same institute
L. S. Kokov
Department of kidney and pancreas transplantation (Head – cand. of med. sci. A.V. Pinchuk) at the same institute
R. Sh. Muslimov
Department of computed tomography and magnetic resonance imaging (Head – doct. of med. sci. F.A. Sharifullin) at the same institute
T. V. Bognitskaya
Department of ultrasound diagnostics and mini-invasive treatment methods (Head – prof., doct. of med. sci. E.U. Trofimova) at the same institute
M. V. Parkhomenko
Interventional radiology department (Head – corresponding member of RAMSci, prof. L.S. Kokov) at the same institute
E. A. Grishina
Department of ultrasound diagnostics and mini-invasive treatment methods (Head – prof., doct. of med. sci. E.U. Trofimova) at the same institute
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Review
For citations:
Khubutia M.Sh., Pinchuk A.V., Shmarina N.V., Dmitriev I.V., Storozhev R.V., Kokov L.S., Muslimov R.Sh., Bognitskaya T.V., Parkhomenko M.V., Grishina E.A. VASCULAR COMPLICATIONS AFTER KIDNEY TRANSPLANTATION. Russian Journal of Transplantology and Artificial Organs. 2013;15(4):31-39. (In Russ.) https://doi.org/10.15825/1995-1191-2013-4-31-39
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