Preview

Вестник трансплантологии и искусственных органов

Расширенный поиск

НЕКОМПАКТНАЯ КАРДИОМИОПАТИЯ

https://doi.org/10.15825/1995-1191-2016-4-146-156

Полный текст:

Аннотация

В статье представлен обзор литературы по различным аспектам некомпактной кардиомиопатии. Некомпактная кардиомиопатия – относительно редкое врожденное заболевание сердца, характеризующееся чрезмерным развитием трабекулярной сети и глубокими межтрабекулярными впадинами миокарда желудочков. Наиболее часто встречается неуплотненный миокард левого желудочка (НМЛЖ). НМЛЖ может быть изолированным или сосуществовать с другими кардиальными и системными аномалиями. Неуплотнение диагностируют, используя эхокардиографию или магнитно-резонансную томографию. Клинические проявления варьируют в широких пределах – от бессимптомных пациентов до пациентов с желудочковыми аритмиями, застойной сердечной недостаточностью и тромбоэмболиями. Некомпактный миокард является нерешенной клинической задачей в силу недостаточной точности неинвазивной диагностики и стратификации пациентов, определения прогноза и в ряде случаев – тактики их лечения.

Об авторах

И. М. Ильинский
ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России ГБОУ ВПО «Первый Московский государственный медицинский университет имени И.М. Сеченова» Минздрава России
Россия

Кафедра трансплантологии и искусственных органов ГБОУ ВПО «Первый Московский
государственный медицинский университет имени И.М. Сеченова» Минздрава России

Адрес: 123182, Москва, ул. Щукинская, д. 1. Тел. (926) 811-84-55



Н. П. Можейко
ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России
Россия

Москва, Российская Федерация



А. О. Шевченко
ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России ГБОУ ВПО «Первый Московский государственный медицинский университет имени И.М. Сеченова» Минздрава России
Россия

Кафедра трансплантологии и искусственных органов ГБОУ ВПО «Первый Московский
государственный медицинский университет имени И.М. Сеченова» Минздрава России, Москва, Российская Федерация



Список литературы

1. Шевченко АО, Ильинский ИМ, Можейко НП, Зубкова ЕА, Олефиренко ГА, Шевченко ОП. Некомпактный миокард у потенциальных реципиентов сердца: морфологическая верификация. Вестник трансплантологии и искусственных органов. 2016; XVIII (Приложение): 45. Shevchenko AO, Il’inskij IM, Mozhejko NP, Zubkova EA, Olefi renko GA, Shevchenko OP. Nekompaktnyj miokard u potencial’nyh recipientov serdca: morfologicheskaya verifi kaciya. Vestnik transplantologii i iskusstvennyh organov = Russian journal of transplantology and artifi cial organs. 2016; XVIII (Prilozhenie): 45.

2. Готье СВ, Шевченко АО, Попцов ВН. Пациент с трансплантированным сердцем. М.–Тверь: Триада, 2014: 144. Gautier SV, Shevchenko AO, Poptsov VN. Pacient s transplantirovannym serdcem. M.–Tver’: Triada, 2014: 144.

3. Палеев ФН, Абудеева ИС, Демина ОВ, Ведерников АВ, Степанова ЕА. Некомпактный миокард. Кардиология. 2011; 5: 91–96. Paleev FN, Abudeeva IS, Demina OV, Vedernikov AV, Stepanova EA. Nekompaktnyj miokard. Kardiologiya. 2011; 5: 91–96.

4. Благова ОВ, Недоступ АВ, Седов ВП, Гагарина НВ, Коган ЕА, Сулимов ВА, Фролова ЮВ и др. Некомпактный миокард как первичный феномен или следствие дисфункции миокарда: клинические маски синдрома. Кардиология. 2012; 11: 17– 26. Blagova OV, Nedostup AV, Sedov VP, Gagarina NV, Kogan EA, Sulimov VA, Frolova YuV i dr. Nekompaktnyj miokard kak pervichnyj fenomen ili sledstvie disfunkcii miokarda: klinicheskie maski sindroma. Kardiologiya. 2012; 11: 17–26.

5. Стукалова ОВ, Ширяев ГА, Нарусов ОН, Терновой СК. Некомпактный миокард. Кардиология. 2012; 9: 94–96. Stukalova OV, Shiryaev GA, Narusov ON, Ternovoj SK. Nekompaktnyj miokard. Kardiologiya. 2012; 9: 94–96.

6. Голухова ЕЗ, Шомахов РА. Некомпактный миокард левого желудочка. Креативная кардиология. 2013; 1: 35–45. Goluhova EZ, Shomahov RA. Nekompaktnyj miokard levogo zheludochka. Kreativnaya kardiologiya. 2013; 1: 35–45.

7. Dusek J, Ostádal B, Duskova M. Postnatal persistence of spongy myocardium with embryonic blood supply. Arch. Pathol. 1975; 99: 312–317.

8. Engberding R, Bender F. Identification of a rare congenital anomaly of the myocardium by two-dimensional echocardiography: persistence of isolated myocardial sinusoids. Am. J. Cardiol. 1984 Jun 1; 53 (11): 1733– 1734.

9. Chin TK, Perloff JK, Williams RG, Jue K, Mohrmann R. Isolated noncompaction of left ventricular myocardium. A study of eight cases. Circulation. 1990; 82: 507–513.

10. Maron BJ, Towbin JA, Thiene G et al. Contemporary definitions and classifi cation of the cardiomyopathies: an American Heart Association Scientifi c Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation. 2006; 113 (14): 1807–1816. doi: 10.1161/circulationaha.106.174287.6.

11. Elliott P, Andersson B, Arbustini E et al. Classifi cation of the cardiomyopathies: a position statement from the european society of cardiology working group on myocardial and pericardial diseases. European Heart Journal. 2008; 29 (2): 270–276. doi: 10.1093/eurheartj/ehm342.

12. Habib G, Charron P, Eicher JC et al. Isolated left ventricular noncompaction in adults: clinical and echocardiographic features in 105 patients. Results from a French registry. Eur. J. Heart Fail. 2011; 13: 177–185.

13. Baskurt M, Kalyoncuoglu M, Kucukoglu S. Noncompaction cardiomyopathy and dextroversion of the heart. Herz. 2011 Feb; 36 (1): 33–36. doi: 10.1007/s00059-010- 3386-3.

14. Pignatelli RH, McMahon CJ, Dreyer WJ, Denfi eld SW, Price J, Belmont JW. Clinical characterization of left ventricular noncompaction in children: a relatively common form of cardiomyopathy. Circulation. 2003; 108 (21): 2672–2678.

15. Engberding R, Yelbuz TM, Breithardt G. Isolated noncompaction of the left ventricular myocardium – a review of the literature two decades after the initial case description. Clin. Res. Cardiol. 2007 Jul; 96 (7): 481– 488.

16. Finsterer J, Stollberger C, Schubert B. Acquired left ventricular noncompaction as a cardiac manifestation of neuromuscular disorders. Scand. Cardiovasc. J. 2008; 42 (1): 25–30. doi: 10.1080/14017430701744451.

17. Captur G, Nihoyannopoulos P. Left ventricular noncompaction: genetic heterogeneity, diagnosis and clinical course. Int. J. Cardiol. 2010 Apr 15; 140 (2): 145– 153.

18. Ilyas S, Ganote C, Lajoie D, Robertson J, Cline-Parhamovich K. Sudden death and isolated right ventricular noncompaction cardiomyopathy: report of 2 autopsied adult cases. Am. J. Forensic Med. Pathol. 2013; 34: 225–227. doi: 10.1097/PAF.0b013e3182a0a46c.

19. Marcus FI, McKenna WJ, Sherrill D, Basso C, Bauce B, Bluemke DA, Calkins H et al. Diagnosis of arrhythmogenic right ventricular cardiomyopathy / dysplasia: proposed modifi cation of the task force criteria. Circulation. 2010; 121: 1533–1541. doi: 10.1161/CIRCULATIONAHA.108.840827.

20. Wlodarska EK, Wozniak O, Konka M, Piotrowska-Kownacka D, Walczak E, Hoffman P. Isolated ventricular noncompaction mimicking arrhythmogenic right ventricular cardiomyopathy – a study of nine patients. Int. J. Cardiol. 2010; 145: 107–111. doi: 10.1016/j.ijcard.2009.05.062.

21. Borreguero LJJ, Corti R, de Soria RF, Osende JI, Fuster V, Badimon JJ. Images in cardiovascular medicine. Diagnosis of isolated noncompaction of the myocardium by magnetic resonance imaging. Circulation. 2002; 105 (21): E177–E178.

22. Sato Y, Matsumoto N, Matsuo S et al. Right ventricular involvement in a patient with isolated noncompaction of the ventricular myocardium. Cardiovascular Revascularization Medicine. 2007; 8 (4): 275–277. doi: 10.1016/j.carrev.2006.05.003.

23. Rao G, Tauras J. Biventricular Noncompaction Cardiomyopathy in an Adult with Unique Facial Dysmorphisms: Case Report and Brief Review. Case Rep. Cardiol. 2015; 2015: 831341. Published online 2015 Jul 21. doi: 10.1155/2015/831341.

24. Stahli BE, Gebhard C, Biaggi P et al. Left ventricular non-compaction: prevalence in congenital heart disease. Int. J. Cardiol. 2013; 167: 2477–2481.

25. Fazio G, Pipitone S, Iacona MA, Marchм S, Mongiovм M, Zito R, Sutera L, Novo S. The noncompaction of the left ventricular myocardium: our paediatric experience. J. Cardiovasc. Med. (Hagerstown). 2007 Nov; 8 (11): 904–908.

26. Chung JW, Lee SJ, Lee JH, Chin JY, Lee HJ, Lee CJ. Isolated left ventricular noncompaction cardiomyopathy accompanied by severe mitral regurgitation. Korean Circ. J. 2009; 39 (11): 494–498. doi: 10.4070/kcj.2009.39.11.494.

27. George KM, Badhwar V. Sustainable myocardial recovery after mitral reconstruction for left ventricular noncompaction. Ann. Thorac. Surg. 2010; 89 (4): 1283–1284. doi: 10.1016/j.athoracsur.2009.08.076.

28. Ali SKM, Omran AS, Najm H, Godman MJ. Noncompaction of ventricular myocardium with mitral regurgitation and preserved ventricular function. J. Am. Soc. Echocardiogr. 2004; 17 (1): 87–90.

29. Ali SKM, Abu-Sulaiman R, Agouba RB. Noncompaction cardiomyopathy: A new mechanism for mitral regurgitation with distinct clinical, echocardiographic features and pathological correlations. J. Saudi Heart. Assoc. 2015 Apr; 27 (2): 71–78.

30. Igarashi T, Takase S, Satokawa H, Wakamatsu H, Kurosawa H, Yokoyama H. Left ventricular noncompaction complicated by mitral valve prolapse: report of a case. Surg. Today. 2013; 43 (7): 818–820. doi: 10.1007/s00595-012-0271-0.

31. Curcic P, Knez I, Kandolf R, Gamillscheg A. A rare case of left ventricular non- compaction in early infancy. Eur. J. Cardiothoracic Surg. 2012; 41 (4): 960. doi: 10.1093/ejcts/ezr121.

32. Betrian Blasco P, Gallardo Agromayor E. Ebstein’s anomaly and left ventricular noncompaction association. International Journal of Cardiology. 2007; 119 (2): 264–265. doi: 10.1016/j.ijcard.2006.07.147.

33. McGee M, Collins N. Ebstein’s Anomaly, Left Ventricular Noncompaction, and Sudden Cardiac Death. Case Rep. Cardiol. 2015; 2015: 854236. Published online 2015 Jul 9. doi: 10.1155/2015/854236.

34. Кнышов ГВ, Гогаева ЕК, Руденко АВ, Дзахоева ЛС, Лазоришинец ВВ, Паничкин ЮВ, Сало СВ. Ныряющие артерии – норма или патология? Международный медицинский журнал. 2006; 1: 14–18. Knyshov GV, Gogaeva EK, Rudenko AV, Dzahoeva LS, Lazorishinec VV, Panichkin YuV, Salo SV. Nyryayushchie arterii – norma ili patologiya? Mezhdunarodnyj medicinskij zhurnal. 2006; 1: 14–18.

35. Тетвадзе ИВ. Миокардиальные мышечные мостики (анатомия, диагностика и лечение): Автореф. дис. … канд. мед. наук. М., 2011. Tetvadze IV. Miokardial’nye myshechnye mostiki (anatomiya, diagnostika i lechenie): Avtoref. dis. … kand. med. nauk. M., 2011.

36. Бокерия ЛА, Суханов СГ, Стерник ЛИ, Шатахян МП. Миокардиальные мостики. Под ред. Л.А. Бокерия. М., 2013: 158. Bokeriya LA, Suhanov SG, Sternik LI, Shatahyan MP. Miokardial’nye mostiki. Pod red. L.A. Bokeriya. M., 2013: 158.

37. Zambrano E, Marshalko SJ, Jaffe CC et al. Isolated noncompaction of the ventricular myocardium: clinical and molecular aspects of a rare cardiomyopathy. Lab. Invest. 2002; 82: 117–122.

38. Shen Y, Li X, Lu D, Xiao A, Li J. Myocardial Noncompaction Presenting With Myocardial Bridge. Published online 2015 Sep 11. doi: 10.1097/MD.0000000000001425.

39. Weiford BC, Subbarao VD, Mulhern KM. Noncompaction of the ventricular myocardium. Circulation. 2004; 109: 2965–2971.

40. Mohlenkamp S, Hort W, Ge J et al. Update on myocardial bridging. Circulation. 2002; 106: 2616–2622.

41. Basso C, Thiene G, Key-Bojack S et al. Myocardial bridging, a frequent component of the hypertrophic cardiomyopathy phenotype, lacks systematic association with sudden cardiac death. Eur. Heart J. 2009; 30: 1627–1634.

42. Aras D, Tufekcioglu O, Topaloglu S et al. Non-compaction cardiomyopathy associated with myocardial bridging: a frequently overlooked or misdiagnosed cardiomyopathy. Eur. J. Heart Fail. 2006; 8: 760–763.

43. Kucukdurmaz Z, Kizilkan N, Akkoyun DC et al. Isolated left ventricular myocardial non-compaction coexists with myocardial coronary artery bridge as a cause of ischemic ECG changes. Int. J. Cardiol. 2008; 130: e1–e3.

44. Erdogan E, Akkaya M, Bacaksiz A et al. A very rare case of coexistence of ventricular noncompaction cardiomyopathy, myocardial bridging and atherosclerosis. Postepy Kardiol. Interwencyjnej. 2013; 9: 176–178.

45. Tufekcioglu O, Aras D, Sahin O, Ergun K, Hazirolan T, Celenk MK, Demir AD. Two cardiomyopathies in one heart. Echocardiography. 2006; 23: 519–521.

46. Matsukuma S, Eishi K, Hashizume K, Oshitomi T, Ariyoshi T, Taniguchi S, Hisatomi K et al. Arrhythmogenic left ventricular cardiomyopathy associated with noncompaction. Ann. Thorac. Surg. 2010; 90: 2044–2046. doi: 10.1016/j.athoracsur.2010.06.004.

47. Honarbakhsh S, Suman-Horduna I, Mantziari L, Ernst S. Arrhythmogenic Right Ventricle in Left Ventricular Non-compaction – In response to «Right Ventricular Ablation as a Therapeutic Option for Left Ventricular Hypertrabeculation / noncompaction». Indian Pacing Electrophysiol J. 2014; 14: 105–107. eCollection 2014.

48. Aras D, Ozeke O, Cay S, Ozcan F, Baser K, Dogan U, Unlu M et al. Arrhythmogenic Noncompaction Cardiomyopathy: Is There an Echocardiographic Phenotypic Overlap of Two Distinct Cardiomyopathies? J. Cardiovasc. Ultrasound. 2015 Sep; 23 (3): 186–190. Published online 2015 Sep 24. doi: 10.4250/jcu.2015.23.3.186.

49. Song ZZ. A combination of right ventricular hypertrabeculation/noncompaction and arrhythmogenic right ventricular cardiomyopathy: a syndrome? Cardiovasc. Ultrasound. 2008; 6: 63. doi: 10.1186/1476-7120-6-63.

50. Woo JS, Perez-Rosendahl M, Haydel D, Perens G, Fishbein MC. A novel association of biventricular cardiac noncompaction and diabetic embryopathy: case report and review of the literature. Pediatr. Dev. Pathol. 2015 Jan-Feb; 18 (1): 71–75. doi: 10.2350/14-07- 1532-CR.1.

51. Ichida F, Hamamichi Y, Miyawaki T et al. Clinical features of isolated noncompaction of the ventricular myocardium: long-term clinical course, hemodynamic properties, and genetic background. Journal of the American College of Cardiology. 1999; 34 (1): 233– 240. doi: 10.1016/s0735-1097(99)00170-9.

52. Stollberger C, Blazek G, Wegner C, Finsterer J. Neurological comorbidity affects prognosis in left ventricular hypertrabeculation/noncompaction. Heart Lung. 2012; 41 (6): 594–598. doi: 10.1016/j.hrtlng.2012.03.002.

53. Bleyl SB, Mumford BR, Brown-Harrison M-C et al. Xq28-linked noncompaction of the left ventricular myocardium: prenatal diagnosis and pathologic analysis of affected individuals. The American Journal of Medical Genetics. 1997; 72 (3): 257–265.

54. Bleyl SB, Mumford BR, Thompson V et al. Neonatal, lethal noncompaction of the left ventricular myocardium is allelic with Barth syndrome. American Journal of Human Genetics. 1997; 61 (4): 868–872. doi: 10.1086/514879.

55. Ichida F, Tsubata S, Bowles KR et al. Novel gene mutations in patients with left ventricular noncompaction or Barth syndrome. Circulation. 2001; 103 (9): 1256–1263. doi: 10.1161/01.cir.103.9.1256.

56. Sasse-Klaassen S, Gerull B, Oechslin E, Jenni R, Thierfelder L. Isolated noncompaction of the left ventricular myocardium in the adult is an autosomal dominant disorder in the majority of patients. The American Journal of Medical Genetics. 2003; 119 (2): 162–167.

57. Kenton AB, Sanchez X, Coveler KJ et al. Isolated left ventricular noncompaction is rarely caused by mutations in G4.5, alpha-dystrobrevin and FK Binding Protein- 12. Mol. Genet. Metab. 2004; 82: 162–166.

58. Hermida-Prieto M, Monserrat L, Castro-Beiras A et al. Familial dilated cardiomyopathy and isolated left ventricular noncompaction associated with lamin A/C gene mutations. The American Journal of Cardiology. 2004; 94 (1): 50–54. doi: 10.1016/j.amjcard.2004.03.029.

59. Klaassen S, Probst S, Oechslin E et al. Mutations in sarcomere protein genes in left ventricular noncompaction. Circulation. 2008; 117 (22): 2893–2901. doi: 10.1161/circulationaha.107.746164.

60. Luxán G, Casanova JC, Martínez-Poveda B et al. Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nature Medicine. 2013; 19 (2): 193–201. doi: 10.1038/nm.3046.

61. Liu Z, Shan H, Huang J, Li N, Hou C, Pu J. A novel lamin A/C gene missense mutation (445 V > E) in immunoglobulin- like fold associated with left ventricular non-compaction. Europace. 2015 Mar 31 [Epub ahead of print].

62. Parent JJ, Towbin JA, Jefferies JL. Left ventricular noncompaction in a family with lamin A/C gene mutation. Tex. Heart Inst. J. 2015; 42 (1): 73–76. doi: 10.14503/THIJ-13- 3843. eCollection 2015.

63. Finsterer J, Zarrouk-Mahjoub S. Lamin A/C Mutations Do Not Cause Left Ventricular Hypertrabeculation/ Noncompaction. Tex. Heart Inst. J. 2015 Jun; 42 (3): 301–302. Published online 2015 Jun 1. doi: 10.14503/THIJ-15-5282.

64. Gati S, Papadakis M, Van Niekerk N, Reed M, Yeghen T, Sharma S. Increased left ventricular trabeculation in individuals with sickle cell anaemia: physiology or pathology? International Journal of Cardiology. 2013; 168 (2): 1658–1660. doi: 10.1016/j.ijcard.2013.03.039.

65. Gati S, Papadakis M, Papamichael ND et al. Reversible de novo left ventricular trabeculations in pregnant women: implications for the diagnosis of left ventricular noncompaction in low-risk populations. Circulation. 2014; 130 (6): 475–483. doi: 10.1161/circulationaha.114.008554.

66. Arbustini E, Weidemann F, Hall JL. Left ventricular noncompaction: a distinct cardiomyopathy or a trait shared by different cardiac diseases? Journal of the American College of Cardiology. 2014; 64 (17): 1840–1850. doi: 10.1016/j.jacc.2014.08.030.

67. Oechslin E, Jenni R. Left ventricular non-compaction revisited: a distinct phenotype with genetic heterogeneity? European Heart Journal. 2011; 32 (12): 1446–1456. doi: 10.1093/eurheartj/ehq508.

68. Bainbridge MN, Davis EE, Choi WY, Dickson A, Martinez HR, Wang M, Dinh H et al. Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction. Circ. Cardiovasc. Genet. 2015 Aug; 8 (4): 544–552. doi: 10.1161/CIRCGENETICS.115.001026.

69. Postma AV, van Engelen K, van de Meerakker J et al. Mutations in the sarcomere gene MYH7 in Ebstein anomaly. Circulation: Cardiovascular Genetics. 2011; 4 (1): 43–50. doi: 10.1161/circgenetics.110.957985.

70. Kauer F, Geleijnse ML, van Dalen BM. Role of left ventricular twist mechanics in cardiomyopathies, dance of the helices. World J. Cardiol. 2015 Aug 26; 7 (8): 476–482. Published online 2015 Aug 26. doi: 10.4330/wjc.v7.i8.476 PMCID: PMC4549781.

71. Абрикосов АИ. Частная патологическая анатомия. Т. 2. М.: Медгиз, 1947: 7–27. Abrikosov AI. Chastnaya patologicheskaya anatomiya. T. 2. М.: Medgiz, 1947: 7–27.

72. Peters F, Khandheria BK, Libhaber E, Maharaj N, Dos Santos C, Matioda H, Essop MR. Left ventricular twist in left ventricular noncompaction. Eur. Heart J. Cardiovasc. Imaging. 2014; 15: 48–55. doi: 10.1093/ehjci/jet076.

73. Nemes A, Kalapos A, Domsik P, Forster T. Identification of left ventricular «rigid body rotation» by three-dimensional speckle-tracking echocardiography in a patient with noncompaction of the left ventricle: a case from the MAGYAR-Path Study. Echocardiography. 2012; 29: E237–E240. doi: 10.1111/j.1540-8175.2012.01767.x.

74. van Dalen BM, Caliskan K, Soliman OI, Kauer F, van der Zwaan HB, Vletter WB, van Vark LC et al. Diagnostic value of rigid body rotation in noncompaction cardiomyopathy. J. Am. Soc. Echocardiogr. 2011; 24: 548–555. doi: 10.1016/j.echo.2011.01.002.

75. Nemes A, Havasi K, Forster T. «Rigid body rotation» of the left ventricle in hypoplastic right-heart syndrome: a case from the three-dimensional speckle-tracking echocardiographic MAGYAR-Path Study. Cardiol. Young. 2015; 25: 768–772. doi: 10.1017/S1047951114000973.

76. Ritter M, Oechslin E, Sütsch G, Attenhofer C, Schneider J, Jenni R. Isolated noncompaction of the myocardium in adults. Mayo Clinic Proceedings. 1997; 72 (1): 26– 31. doi: 10.4065/72.1.26.

77. Gerger D, Stollberger C, Grassberger M, Gerecke B, Andresen H, Engberding R, Finsterer J. Pathomorphologic fi ndings in left ventricular hypertrabeculation/noncompaction of adults in relation to neuromuscular disorders. Int. J. Cardiol. 2013; 169 (4): 249–253. doi: 10.1016/j.ijcard.2013.08.138.

78. Stollberger C, Finsterer J. Noncompaction in Healthy Subjects, Dilated and Hypertrophic Cardiomyopathy, and Neuromuscular Disorders is the Same Entity. Iran J. Pediatr. 2015 Apr; 25 (2): e511. Published online 2015 Apr 18. doi: 10.5812/ijp.511.

79. Andre F, Burger A, LoЯnitzer D, Buss SJ, Abdel-Aty H, Gianntisis E, Steen H, Katus HA. Reference values for left and right ventricular trabeculation and non-compacted myocardium. Int. J. Cardiol. 2015 Apr 15; 185: 240–247. doi: 10.1016/j.ijcard.2015.03.065.

80. Jenni R, Oechslin E, Schneider J, Attenhofer Jost C, Kaufmann PA. Echocardiographic and pathoanatomical characteristics of isolated left ventricular non- compaction: a step towards classifi cation as a distinct cardiomyopathy. Heart. 2001; 86: 666–671. doi: 10.1136/heart.86.6.666.

81. Stöllberger C, Finsterer J, Blazek G. Left ventricular hypertrabeculation/noncompaction and association with additional cardiac abnormalities and neuromuscular disorders. Am. J. Cardiol. 2002; 90: 899–902.

82. Khosroshahi AG, Zanjani KS, Kocharian A, Zeinaloo A, Kiani A, Rad EM. A novel method for quantifi cation of left ventricular noncompaction using two-dimensional echocardiography in children. Iran J. Pediatr. 2013; 23 (5): 519–524.

83. Fazio G, Novo G, D’Angelo L, Visconti C, Sutera L, Grassedonio E, Galia M et al. Magnetic resonance in isolated noncompaction of the ventricular myocardium. Int. J. Cardiol. 2010 Apr 30; 140 (3): 367–369.

84. Petersen SE, Selvanayagam JB, Wiesmann F et al. Left ventricular non-compaction: insights from cardiovascular magnetic resonance imaging. J. Am. Coll. Cardiol. 2005; 46: 101–105. doi: 10.1016/j.jacc.2005.03.045.

85. Jacquier A, Thuny F, Jop B et al. Measurement of trabeculated left ventricular mass using cardiac magnetic resonance imaging in the diagnosis of left ventricular non- compaction. Eur. Heart J. 2010; 31: 1098–1104.

86. Zhang Y, He L, Cai J, Lv T, Yi Q, Xu Y, Liu L et al. Measurements in Pediatric Patients with Cardiomyopathies: Comparison of Cardiac Magnetic Resonance Imaging and Echocardiography. Cardiology. 2015; 131 (4): 245–250. doi: 10.1159/000381418.

87. Captur G, Muthurangu V, Cook C, Flett AS, Wilson R, Barison A, Sado DV et al. Quantifi cation of left ventricular trabeculae using fractal analysis. J. Cardiovasc. Magn. Reson. 2013; 15: 36. doi: 10.1186/1532-429X-15-36.

88. Steffel J, Kobza R, Oechslin E, Jenni R, Duru F. Electrocardiographic characteristics at Initial diagnosis in patients with isolated left ventricular noncompaction. Am. J. Cardiol. 2009; 104: 984–989.

89. Garcia-Pavia P, de la. Left ventricular noncompaction: a genetic cardiomyopathy looking for diagnostic criteria. J. Am. Coll. Cardiol. 2014; 64: 1981–1983. doi: 10.1016/j.jacc.2014.08.034.

90. Oechslin EN, Attenhofer Jost CH, Rojas JR, Kaufmann PA, Jenni R. Long-term follow- up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis. Journal of the American College of Cardiology. 2000; 36 (2): 493– 500. doi: 10.1016/s0735-1097(00)00755-5.

91. Zemrak F, Ahlman MA, Captur G et al. The relationship of left ventricular trabeculation to ventricular function and structure over a 9.5-year follow-up: the MESA study. Journal of the American College of Cardiology. 2014; 64 (19): 1971–1980. doi: 10.1016/j.jacc.2014.08.035.

92. Brouwers C, Caliskan K, Bos S, Van Lennep JE, Sijbrands EJ, Kop WJ, Pedersen SS. Health Status and Psychological Distress in Patients with Non-compaction Cardiomyopathy: The Role of Burden Related to Symptoms and Genetic Vulnerability. Int. J. Behav. Med. 2015 Dec; 22 (6): 717–725. doi: 10.1007/s12529-015-9475-1.

93. Burke A, Mont E, Kutys R, Virmani R. Left ventricular noncompaction: a pathological study of 14 cases. Hum. Pathol. 2005; 36 (4): 403–411.

94. Lee Ga-Hee, Kim Dae-Kyeong, Song Yeo-Jeong, Yang Ju-Il, Shin Ho-Cheol, Ong Sungmoon, Lee Ho Young. Stroke in a Young Individual with Left Ventricular Noncompaction and Left Atrium Standstill. Korean Circ. J. 2015 Sep; 45 (5): 432–438. Published online 2014 Dec 9. doi: 10.4070/kcj.2015.45.5.432.

95. Kobza R, Jenni R, Erne P, Oechslin E, Duru F. Implantable cardioverter-defi brillators in patients with left ventricular noncompaction. Pacing and Clinical Electrophysiology. 2008; 31 (4): 461–467. doi: 10.1111/j.1540-8159.2008.01015.x.

96. Bertini M, Ziacchi M, Biffi M, Biagini E, Rocchi G, Martignani C, Ferlito M et al. Effects of cardiac resynchronisation therapy on dilated cardiomyopathy with isolated ventricular non-compaction. Heart. 2011 Feb; 97 (4): 295–300. doi: 10.1136/hrt.2010.211607.

97. Qiu Q, Chen YX, Mai JT, Yuan WL, Wei YL, Liu YM, Yang L, Wang JF. Effects of cardiac resynchronization therapy on left ventricular remodeling and dyssynchrony in patients with left ventricular noncompaction and heart failure. Int. J. Cardiovasc. Imaging. 2015 Feb; 31 (2): 329–337. doi: 10.1007/s10554-014-0568-8.

98. Uribarri A, Rojas SV, Avsar M, Hanke JS, Napp LC, Berliner D, Bavendiek U et al. First series of mechanical circulatory support in non-compaction cardiomyopathy: Is LVAD implantation a safe alternative? Int. J. Cardiol. 2015 Oct 15; 197: 128–132. doi: 10.1016/j.ijcard.2015.04.046.

99. Bhat T, Costantino T, Bhat H, Olkovsky Y, Akhtar M, Teli S. Long-term myocardial recovery after mitral valve replacement in noncompaction cardiomyopathy. J.Cardiothorac. Surg. 2011; 6: 124. doi: 10.1186/1749-8090-6-124.

100. Stanton C, Bruce C, Connolly H et al. Isolated left ventricular noncompaction syndrome. Am. J. Cardiol. 2009; 104: 1135–1138.

101. Aras D, Tufekcioglu O, Ergun K et al. Clinical features of isolated ventricular noncompaction in adults longterm clinical course, echocardiographic properties, and predictors of left ventricular failure. J. Card. Fail. 2006; 12: 726–733.

102. Bharucha T, Lee KJ, Daubeney PE, Nugent AW, Turner C, Sholler GF, Robertson T et al. NACCS (National Australian Childhood Cardiomyopathy Study) Investigators. Sudden death in childhood cardiomyopathy: results from a long-term national population-based study. J. Am. Coll. Cardiol. 2015 Jun 2; 65 (21): 2302–2310. doi: 10.1016/j.jacc.2015.03.552.


Для цитирования:


Ильинский И.М., Можейко Н.П., Шевченко А.О. НЕКОМПАКТНАЯ КАРДИОМИОПАТИЯ. Вестник трансплантологии и искусственных органов. 2016;18(4):146-156. https://doi.org/10.15825/1995-1191-2016-4-146-156

For citation:


Iljinsky I.M., Mozheyko N.P., Shevchenko A.O. NONCOMPACTION CARDIOMYOPATHY. Russian Journal of Transplantology and Artificial Organs. 2016;18(4):146-156. (In Russ.) https://doi.org/10.15825/1995-1191-2016-4-146-156

Просмотров: 524


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 1995-1191 (Print)
ISSN 2412-6160 (Online)