КЛИНИЧЕСКОЕ ЗНАЧЕНИЕ ЦИТОМЕГАЛОВИРУСНОЙ ИНФЕКЦИИ У ДЕТЕЙ ПОСЛЕ ТРАНСПЛАНТАЦИИ ПЕЧЕНИ
https://doi.org/10.15825/1995-1191-2016-1-67-77
Аннотация
Трансплантация печени является единственным возможным путем лечения многих форм хронических заболеваний печени терминальной стадии у детей. Цитомегаловирус – наиболее распространенная и значимая инфекция у детей после трансплантации печени с развитием эпизодов ЦМВ-инфекции (ЦМВИ) или ЦМВ-заболевания. ЦМВИ ассоциирована с повышенным риском потери трансплантата. В обзоре литературы представлены такие аспекты, как этиология и эпидемиология ЦМВИ после трансплантации печени детям, применяемые подходы диагностики и профилактики ЦМВИ, алгоритмы дозирования валганцикловира, а также методы профилактики осложнений течения ЦМВИ. Также представлены последние данные о текущих стратегиях профилактики ЦМВИ в мировой практике.
Об авторах
О. М. Цирульникова
ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России;
Кафедра трансплантологии и искусственных органов ГБОУ ВПО «Первый МГМУ им. И.М. Сеченова»
Россия
Москва
Россия
Москва
И. В. Жилкин
ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России
Россия
123182, г. Москва, ул. Щукинская, д. 1
Россия
123182, г. Москва, ул. Щукинская, д. 1
Д. Г. Ахаладзе
ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России
Россия
Москва
Россия
Москва
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Рецензия
Для цитирования:
Цирульникова О.М., Жилкин И.В., Ахаладзе Д.Г. КЛИНИЧЕСКОЕ ЗНАЧЕНИЕ ЦИТОМЕГАЛОВИРУСНОЙ ИНФЕКЦИИ У ДЕТЕЙ ПОСЛЕ ТРАНСПЛАНТАЦИИ ПЕЧЕНИ. Вестник трансплантологии и искусственных органов. 2016;18(1):67-77. https://doi.org/10.15825/1995-1191-2016-1-67-77
For citation:
Tsiroulnikova O.M., Zhilkin I.V., Akhaladze D.G. CLINICAL SIGNIFICANCE OF CYTOMEGALOVIRUS INFECTION IN PEDIATRIC LIVER TRANSPLANT RECIPIENTS. Russian Journal of Transplantology and Artificial Organs. 2016;18(1):67-77. (In Russ.) https://doi.org/10.15825/1995-1191-2016-1-67-77
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