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Russian Journal of Transplantology and Artificial Organs

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SPLENIC ARTERY EMBOLIZATION IN PATIENTS UNDERGOING ORTHOTOPIC LIVER TRANSPLANTATION

https://doi.org/10.15825/1995-1191-2016-1-17-21

Abstract

Aim: to analyze the results of embolization of the splenic artery in fi ve patients after orthotopic liver transplantation.

Materials and methods. Embolization of the splenic artery was performed 6 times in fi ve (3.2%) of 158 patients who underwent orthotopic liver transplantation in terms from 2 months up to 10 years after surgery. The indications for embolization in 3 cases were the manifestations of hypersplenism syndrome, in 3 others – splenic artery steal syndrome.

Results. In 3 cases of splenic artery embolization, performed in connection with the manifestations of hypersplenism: 2 – recurrent disease, 1 – splenic infarction. In all these cases a splenectomy was required. In 3 cases when embolization was performed in connection with the display of the splenic artery steal syndrome remission was achieved, splenectomy was not required.

Conclusion. Splenic artery embolization can be considered as a method of treating patients with manifestations of steal syndrome and hypersplenism after orthotopic liver transplantation. The most pronounced effect was achieved in patients with a predominance of manifestations of steal syndrome.

About the Authors

D. A. Granov
Russian Federal Research Center for Radiology and Surgical Technologies of the Ministry of Healthcare of the Russian Federation
Russian Federation
70, Leningradskaya st., p. Pesochny, St. Petersburg, 197758


P. G. Tarazov
Russian Federal Research Center for Radiology and Surgical Technologies of the Ministry of Healthcare of the Russian Federation
Russian Federation
St. Petersburg


A. A. Polikarpov
Russian Federal Research Center for Radiology and Surgical Technologies of the Ministry of Healthcare of the Russian Federation
Russian Federation
St. Petersburg


V. V. Borovik
Russian Federal Research Center for Radiology and Surgical Technologies of the Ministry of Healthcare of the Russian Federation
Russian Federation
St. Petersburg


I. O. Rutkin
Russian Federal Research Center for Radiology and Surgical Technologies of the Ministry of Healthcare of the Russian Federation
Russian Federation
St. Petersburg


I. I. Tileubergenov
Russian Federal Research Center for Radiology and Surgical Technologies of the Ministry of Healthcare of the Russian Federation
Russian Federation
St. Petersburg


References

1. Altaca G, Scigliano E, Guy SR, Sheiner P A, Reich DJ, Schwartz ME et al. Persistent hypersplenism early after liver transplant: the role of splenectomy. Transplantation. 1997 Nov; 64 (10): 1481–1483.

2. Neumann UP, Langrehr JM, Kaisers U, Lang M, Schmitz V, Neuhaus P. Simultaneous splenectomy increases risk for opportunistic pneumonia in patients after liver transplantation. Transplant International. 2002 May; 15 (5): 226–232.

3. Lüsebrink R, Blumhardt G, Lohmann R, Bachmann S, Knoop M, Lemmens HP. Does concommitant splenectomy raise the mortality of liver transplant recipients? Transplant International. 1994 Dec; 7 (S1): 634–636.

4. Palsson B, Hallen M, Forsberg AM, Alwmark A. Partial splenic embolization: long-term outcome. Langenbecks Arch Surg. 2003 Feb; 387 (11–12): 421–426.

5. Alvarez D, Gerona S, Waisburg Z, Ciardullo M, de Santibanes E, Mastai R. Splanchnic hyperemia after liver transplantation in patients with end-stage liver disease. Liver Transpl Surg. 1998; 4: 300–303.

6. Руткин ИО, Таразов ПГ, Гранов ДА, Осовских ВВ, Генералов МИ, Жеребцов ФК и др. Возможности эмболизации селезеночной артерии в лечении «синдрома обкрадывания» после ортотопической трансплантации печени. Трансплантология. 2010 Май; 1: 26–30. Rutkin IO, Tarazov PG, Granov DA, Osovskikh VV, Generalov MI, Zherebtsov FK et al. Capabilities of splenic artery embolization in the treatment of steal syndrome after orthotopic liver transplantation. Transplantologia. 2010 May; 1: 26–30.

7. N’Kontchou G, Seror O, Bourcier V et al. Partial splenic embolization in patients with cirrhosis: effi cacy, tolerance and long-term outcome in 32 patients. Eur J Gastroenterol Hepatol. 2005 Feb; 17 (2): 179–184.

8. Murata K, Shiraki K, Takase K et al. Long term followup for patients with liver cirrhosis after partial splenic embolization. Hepatogastroenterology. 1996 Sep-Oct; 43 (11): 1212–1217.

9. Ohmoto K, Iguchi Y, Miyake I et al. Long-term evaluation of partial splenic embolization for liver cirrhosis and hepatocellular carcinoma accompanied by hypersplenism. Hepatology Research. 1998 Jun; 11 (2): 73–83.

10. Herrero JI, Sangro B, Quiroga J et al. Partial splenic embolization in the treatment of thrombocytopenia after liver transplantation. Transplantation. 1997 Feb; 63 (3): 482–484.

11. Sockrider CS, Boykin KN, Green J et al. Partial splenic embolization for hypersplenism before and after liver transplantation. Clin Transplant. 2002; 16 (7): 59–61.

12. Sakai T, Shiraki K, Inoue H et al. Complications of partial splenic embolization in cirrhotic patients. Dig Dis Sci. 2002 Feb; 47 (2): 388–391.


Review

For citations:


Granov D.A., Tarazov P.G., Polikarpov A.A., Borovik V.V., Rutkin I.O., Tileubergenov I.I. SPLENIC ARTERY EMBOLIZATION IN PATIENTS UNDERGOING ORTHOTOPIC LIVER TRANSPLANTATION. Russian Journal of Transplantology and Artificial Organs. 2016;18(1):17-21. (In Russ.) https://doi.org/10.15825/1995-1191-2016-1-17-21

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ISSN 1995-1191 (Print)