Preview

Вестник трансплантологии и искусственных органов

Расширенный поиск

ИШЕМИЧЕСКОЕ ПОВРЕЖДЕНИЕ АЛЛОТРАНСПЛАНТИРОВАННЫХ ПОЧЕК И АКТИВНОСТЬ МАТРИКСНЫХ МЕТАЛЛОПРОТЕИНАЗ

https://doi.org/10.15825/1995-1191-2011-2-103-109

Полный текст:

Аннотация

В статье приведены данные литературы об ишемическом повреждении аллотрансплантированных почек. Рассматривается взаимосвязь между активностью матриксных металлопротеиназ и ишемическими по- вреждениями почек

Об авторах

М. Л. Арефьев
ФГУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздравсоцразвития РФ, Москва
Россия


М. Г. Минина
Московский координационный центр органного донорства Департамента здравоохранения города Москвы Кафедра трансплантологии и искусственных органов I МГМУ имени И.М. Сеченова, Москва
Россия


И. М. Ильинский
ФГУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздравсоцразвития РФ, Москва Кафедра трансплантологии и искусственных органов I МГМУ имени И.М. Сеченова, Москва
Россия


Список литературы

1. Биленко М.В. Ишемические и реперфузионные по- вреждения органов. М.: Медицина, 1989. 386 с.

2. Ильинский И.М., Розенталь Р.Л. Патология почеч- ных аллотрансплантатов. Рига: Зинатне, 1990. 151 с. 3. Онищенко Н.А., Шумаков В.И., Штенгольц Е.Ш.

3. Консервация органов и тканей / Под ред. акад.

4. Б.В. Петровского. М.: Медицина, 1975. 252 с.

5. Шумаков В.И., Онищенко Н.А., Кирпатовский В.И. Фармакологическая защита трансплантата. М.: Ме-

6. дицина, 1983. 149 с.

7. Ackoundou-N’Guessan C., Bismuth J., Canet S. et al.

8. Partial recovery of delayed graft function due to choles- terol emboli after renal transplantation // Saudi J. Kidney Dis. Transpl. 2008. Vol. 19. No 4. P. 631–635.

9. Bellemare S., Vigneault N., Madore F. et al. Enhanced development of caspase-independent cortical cell death during cold storage in kidneys of non-heart-beating do- nors // Transplantation. 2002. Vol. 73. No 11. P. 1742– 1751.

10. Boros P., Bromberg J.S. New cellular and molecular im- mune pathways in ischemia/reperfusion injury // Am. J. Transplant. 2006. Vol. 6. No 4. P. 652–658.

11. Butterworth P.C., Horsburgh T., Nicholson M.L. Distri- bution and predictive value of apoptosis in biopsies from non-heart-beating donor kidneys // Transplant. Proc. 2000. Vol. 32. No 1. P. 163.

12. Chapman J. Chronic allograft nephropathy. Longitudinal analysis of chronic allograft nephropathy: clinicopatho- logic correlations // Kidney Int. 2005. Vol. 68. P. S108– S112.

13. Chen W., Bennett C.F., Condon T.P. Methoxyethyl modi- fication of phosphorothioate ICAM-1 antisense oligonu- cleotides improves prevention of ischemic/reperfusion injury // Transplant. Proc. 2001. Vol. 33. No 1–2. P. 854.

14. Del Prete D., Ceol M., Anglani F. et al. Early activation of fibrogenesis in transplanted kidneys: a study on serial renal biopsies // Exp. Mol. Pathol. 2009. Vol. 87. No 2. P. 141–145.

15. Dragun D., Hoff U., Park J.K. et al. Ischemia-reperfu- sion injury in renal transplantation is independent of the immunologic background // Kidney Int. 2000. Vol. 58. No 5. P. 2166–2177.

16. Erkasap S., Ates E. L-Arginine-enriched preservation solution decreases ischaemia/reperfusion injury in cani- ne kidneys after long-term cold storage // Nephrol. Dial. Transplant. 2000. Vol. 15. No 8. P. 1224–1227.

17. Fernandez A., Royuela A., Quintas A., Zamora J. Are IL2 receptor antagonist useful in high risk acute tubular necrosis kidney recipients? // Nefrologia. 2007. Vol. 27. No 5. P. 534–536.

18. Furukawa T., Hattori R., Kinukawa T. et al. Analysis of acute rejection episodes during acute tubular necrosis // Transplant-Proc. 1994. Vol. 26. P. 1999–2000.

19. Goldberg L.C., Cook T., Taube D. Pretreatment of renal transplants with anti-CD45 antibodies: optimization of perfusion technique // Transpl. Immunol. 1994. Vol. 2. No 1. P. 27–34.

20. Goldsmith P.J., Ridgway D.M., Pine J.K. et al. Outcomes Following Renal Transplantation after Multi-Organ Retrieval versus Kidney Only Retrieval in Donation after Cardiac Death Donors // XXIII International Congress of the Transplantation Society. Vancouver, August 15–19, 2010. MO16.08.

21. Gong R., Rifai A., Tolbert E.M. et al. Hepatocyte Growth Factor Modulates Matrix Metalloproteinases and Plas- minogen Activator/Plasmin Proteolytic Pathways in Pro- gressive Renal Interstitial Fibrosis // J. Am. Soc. Neph- rol. 2003. Vol. 14. No 12. P. 3047–3060.

22. Goujon J.M., Vandewalle A., Baumert H. et al. Influence of cold-storage conditions on renal function of autotrans- planted large pig kidneys // Kidney Int. 2000. Vol. 58. No 2. P. 838–850.

23. Gwinner W., Hinzmann K., Erdbruegger U. et al. Acute tubular injury in protocol biopsies of renal grafts: preva- lence, associated factors and effect on long-term func- tion // Am. J. Transplant. 2008. Vol. 8. No 8. P. 1684– 1693.

24. Hammad F.T., Davis G., Zhang X., Wheatley A.M. The role of endothelin in early renal cortical reperfusionin re- nal transplantation // Eur. Surg. Res. 2000. Vol. 32. No 6. P. 380–388.

25. Hauet T., Baumert H., Gibelin H. et al. Citrate, acetate and renal medullary osmolyte excretion in urine as pre- dictor of renal changes after cold ischaemia and trans- plantation // Clin. Chem. Lab. Med. 2000. Vol. 38. No 11. P. 1093–1098.

26. Herrero-Fresneda I., Torras J., Lloberas N. et al. Cold ischemia in the absence of alloreactivity induces chro- nic transplant nephropathy through a process mediated by the platelet-activating factor // Transplantation. 2000. Vol. 70. No 11. P. 1624–1631.

27. Hieta N., Impola U., Lopez-Otin C. et al. Matrix metal- loproteinase-19 expression in dermal wounds and by fib- roblasts in culture // J. Invest. Dermatol. 2003. Vol. 121. P. 997–1004.

28. Impola U., Toriseva M., Suomela S. et al. Matrix Metal- loproteinase-19 is expressed by proliferating epithelium but disappears with neoplastic dedifferentiation // Int. J. Cancer. 2003. Vol. 103. P. 709–716.

29. Israni A.K., Li N., Cizman B.B. et al. Association of donor inflammation- and apoptosis-related genoty- pes and delayed allograft function after kidney trans- plantation // Am. J. Kidney Dis. 2008. Vol. 52. No 2. P. 331–339.

30. Jain S., Bicknell G.R., Whiting P.H., Nicholson M.L. Ra- pamycin reduces expression of fibrosis-associated genes in an experimental model of renal ischaemia reperfu- sion injury // Transplant. Proc. 2001. Vol. 33. No 1–2. P. 556–558.

31. Kaden J. J., Dempfle C.E., Grobholz R. et al. Interleu- kin-1 beta promotes matrix metalloproteinase expressi- on and cell proliferation in calcific aortic valve steno- sis // Curr. Top. Microbiol. Immunol. 2004. Vol. 280. P. 165–189.

32. Kaneku H.K., Terasaki P.I. Thirty year trend in kidney transplants: UCLA and UNOS Renal Transplant Regist- ry // Clin. Transpl. 2006. No 1. P. 27.

33. Kato R., Momiyama Y., Ohmori R. et al. Levels of mat- rix metalloproteinase-1 in patients with and without co-

34. ronary artery disease and relation to complex and non- complex coronary plaques // Am. J. of Cardiology. 2005. Vol. 95. No 1. P. 90–92.

35. Khanna A.K., Hosenpud J.S., Plummer M.S., Hosen- pud J.D. Analysis of transforming growth factor-beta and profibrogenic molecules in a rat cardiac allograft model treated with cyclosporine // Transplantation. 2002. Vol. 73. No 10. P. 1543–1549.

36. Kouwenhoven E.A., de Bruin R.W., Bajema I.M. et al. Cold ischemia augments allogeneic-mediated injury in rat kidney allografts // Kidney Int. 2001. Vol. 59. No 3. P. 1142–1148.

37. Kusaka M., Kuroyanagi Y., Ichino M. et al. The incre- ment of serum tissue inhibitor of metalloproteinases 1 (TIMP-1) predicts organ recovery from delayed graft function after kidney transplantation from donors af- ter cardiac death // XXIII International Congress of the Transplantation Society. Vancouver, August 15–19, 2010. P. 39.16.

38. Lauzurica R., Pastor M.C., Bayes B. et al. Pretransplant inflammation: a risk factor for delayed graft function? // J. Nephrol. 2008. Vol. 21. No 2. P. 221–228.

39. Lehtonen S.R., Taskinen E.I., Isoniemi H.M. Histopatho- logical findings in renal allografts at time of transplanta- tion and correlation with onset of graft function // Acta Pathol. Microbiol. Immunol. (Scand). 1999. Vol. 107. P. 945–950.

40. Li M., Nicholls K.M., Becker G.J. Risk factors for late re- nal allograft dysfunction: effects of baseline glomerular size // J. Nephrol. 2002. Vol. 15. No 6. P. 620–625.

41. Lutz J., Luong L.A., Strobl M. et al. The A20 gene pro- tects kidneys from ischaemia/reperfusion injury by sup- pressing pro-inflammatory activation // J. Mol. Med. 2008.

42. Marti H.P. The role of matrix metalloproteinases in the activation of mesangial cells // Transpl. Immunol. 2002. Vol. 9. No 2–4. P. 97–100.

43. Mengel M., Bock O., Priess M. et al. Expression of pro- and antifibrotic genes in protocol biopsies from renal allografts with interstitial fibrosis and tubular atrophy // Clin. Nephrol. 2008. Vol. 69. No 6. P. 408–416.

44. Mikhalski D., Wissing K.M., Ghisdal L. et al. Cold ische- mia is a major determinant of acute rejection and renal graft survival in the modern era of immunosuppression // Transplantation. 2008. Vol. 85. No 7. P. S3–9.

45. Moller H.E., Gaupp A., Dietl K. et al. Tissue pH in hu- man kidney transplants during hypothermic ischemia // Magn. Reson. Imaging. 2000. Vol. 18. No 6. P. 743–751.

46. Nagase H., Visse R., Murphy G. Structure and function of matrix metalloproteinases and TIMPs // Cardiovas- cular Research (Oxford Journals). 2005. Vol. 69. No 3. P. 562–573.

47. Nicholson M.L., Waller J.R., Bicknell G.R. Renal trans- plant fibrosis correlates with intragraft expression of tis- sue inhibitor of metalloproteinase messenger RNA // Br. J. Surg. 2002. Vol. 89. No 7. P. 933–937.

48. Novak K.B., Le H.D., Christison-Lagay E.R. et al. Ef- fects of metalloproteinase inhibition in a murine mo- del of renal ischemia-reperfusion injury // Pediatr. Res. 2010. Vol. 67. No 3. P. 257–262.

49. Oberbauer R., Rohrmoser M., Regele H. et al. Apoptosis of tubular epithelial cells in donor kidney biopsies pre- dicts early renal allograft function // J. Am. Soc. Neph- rol. 1999. Vol. 10. P. 2006–2013.

50. Oda A., Morozumi K., Uchida K. Histological factors of 1-h biopsy influencing the delayed renal function and outcome in cadaveric renal allografts // Clin. Transplant. 1999. Vol. 13. Suppl. 1. P. 6–12.

51. Pallet N., Thervet E., Legendre C., Anglicheau D. Siroli- mus early graft nephrotoxicity: clinical and experimental data // Curr. Drug Saf. 2006. Vol. 1. No 2. P. 179–187.

52. Palomar R., Mayorga M., Ruiz J.C. et al. Markers of fi- brosis in early biopsies of renal transplants // Transplant. Proc. 2005. Vol. 37. No 3. P. 1468–1470.

53. Salahudeen A.K., Huang H., Joshi M. et al. Involve- ment of the mitochondrial pathway in cold storage and rewarming-associated apoptosis of human renal proxi- mal tubular cells // Am. J. Transplant. 2003. Vol. 3. No 3. P. 273–280.

54. Salahudeen A.K., Joshi M., Jenkins J.K. Apoptosis versus necrosis during cold storage and rewarming of human renal proximal tubular cells // Transplantation. 2001. Vol. 72. No 5. P. 798–804.

55. Salahudeen A.K., May W. Reduction in cold ischemia time of renal allografts in the United States over the last decade // Transplant. Proc. 2008. Vol. 40. No 5. P. 1285– 1289.

56. Stamenkovic I. Extracellular matrix remodelling: the role of matrix metalloproteinases // J. Pathol. 2003. Vol. 200. No 4. P. 448–464.

57. Tayebjee M.H., Lip G.Y.H., Blann A.D., MacFadyen R.J. Effects of age, gender, ethnicity, diurnal variation and

58. exercise on circulating levels of matrix metalloprotei- nases (MMP)-2 and -9, and their inhibitors, tissue inhi- bitors of matrix metalloproteinases (TIMP)-1 and -2 // Thrombosis Research. 2005. Vol. 115. No 3. P. 205–210.

59. Tullius S.G., Nieminen-Kelha M., Bachmann U. et al. Induction of heme-oxygenase-1 prevents ischemia/re- perfusion injury and improves long-term graft outcome in rat renal allografts//Transplant. Proc. 2001. Vol. 33. No 1–2. P. 1286–1287.

60. Van den Eijnden M.M., Leuvenink H.G., Ottens P.J. et al. Effect of brain death and non-heart-beating kidney do- nation on renal function and injury: an assessment in the isolated perfused rat kidney // Exp. Clin. Transplant. 2003. Vol. 1. No 2. P. 85–95.

61. Vu T.H., Werb Z. Matrix metalloproteinases: effectors of development and normal physiology // Genes Dev. 2000. Vol. 14. No 17. P. 2123–2133.

62. Yang C.W., Ahn H.J., Han H.J. et al. Pharmacological preconditioning with low-dose cyclosporine or FK506 reduces subsequent ischemia/reperfusion injury in rat kidney // Transplantation. 2001. Vol. 72. No 11. P. 1753– 1759.

63. Zhou M., Zhang Y., Ardans J.A., Wahl L.M. Interferon- gamma differentially regulates monocyte matrix me- talloproteinase-1 and -9 through tumor necrosis factor- alpha and caspase 8 // J. Biol. Chem. 2003. Vol. 278. P. 45406–45413.

64. Ziswiler R., Daniel C., Franz E., Marti H.P. Renal matrix metalloproteinase activity is unaffected by experimental ischemia-reperfusion injury and matrix metalloproteina- se inhibition does not alter outcome of renal function // Exp. Nephrol. 2001. Vol. 9. No 2. P. 118–124.


Рецензия

Для цитирования:


Арефьев М.Л., Минина М.Г., Ильинский И.М. ИШЕМИЧЕСКОЕ ПОВРЕЖДЕНИЕ АЛЛОТРАНСПЛАНТИРОВАННЫХ ПОЧЕК И АКТИВНОСТЬ МАТРИКСНЫХ МЕТАЛЛОПРОТЕИНАЗ. Вестник трансплантологии и искусственных органов. 2011;13(2):103-109. https://doi.org/10.15825/1995-1191-2011-2-103-109

For citation:


Arefjev M.L., Minina M.G., Iljinsky I.M. ISCHEMIC INJURY OF KIDNEY ALLOGRAFTS AND EXPRESSION OF MATRIX METALLOPROTEINASES. Russian Journal of Transplantology and Artificial Organs. 2011;13(2):103-109. (In Russ.) https://doi.org/10.15825/1995-1191-2011-2-103-109

Просмотров: 601


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 1995-1191 (Print)
ISSN 2412-6160 (Online)