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COMBINED LIVER-PANCREAS TRANSPLANTATION: THE FIRST RUSSIAN EXPERIENCE

https://doi.org/10.15825/1995-1191-2010-4-27-32

Abstract

Combined liver-pancreas transplantation is considered to be a reasonable treatment of patients with end-stage liver disease and concomitant insulin-dependent diabetes mellitus, so it may become a standard treatment of this category of patients. As known, diabetes mellitus negatively affects the long-term results of isolated liver transplantation and increases a risk of posttransplant complications. Notwithstanding the widening range of indi- cations for simultaneous liver-pancreas transplantation and advances of transplantology, this operation continues to be a rare event in world medical practice. In May 2010 in Academician V.I. Shumakov Federal Research Cen- ter of Transplantology and Artificial Organs there was performed a first in Russia simultaneous liver-pancreas transplantation to 17-years old recipient, suffering with liver cirrhosis (as a result of autoimmune hepatitis) and concomitant insulin-dependent diabetes mellitus.

In this article we give an overview of indications for simultaneous liver-pancreas transplantation, different ope- rative techniques, immunological aspects and immunosuppression regimes, as well as we describe the first in Russian experience of such transplantation. 

About the Authors

S. V. Gautier
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


O. M. Tsirulnikova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


V. N. Poptsov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


S. V. Arzumanov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


I. V. Pogrebnichenko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


A. A. Ammosov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


Y. E. Lurie
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


N. S. Muratova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


N. V. Gamgiya
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


H. M. Hizroev
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


S. V. Fokin
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


V. V. Pchelnikov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


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Review

For citations:


Gautier S.V., Tsirulnikova O.M., Poptsov V.N., Arzumanov S.V., Pogrebnichenko I.V., Ammosov A.A., Lurie Y.E., Muratova N.S., Gamgiya N.V., Hizroev H.M., Fokin S.V., Pchelnikov V.V. COMBINED LIVER-PANCREAS TRANSPLANTATION: THE FIRST RUSSIAN EXPERIENCE. Russian Journal of Transplantology and Artificial Organs. 2010;12(4):27-32. (In Russ.) https://doi.org/10.15825/1995-1191-2010-4-27-32

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ISSN 1995-1191 (Print)