I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFT
https://doi.org/10.15825/1995-1191-2010-3-112-120
Abstract
It is known, transplantation of organs is accompanied by activation of adaptive immunity (cellular and humoral) and innate immunity in an organism of the recipient. Population of T-lymphocyte which includes some subpopu- lations of cells , such as Тcyt, Th1, Th2 and T-regulatory cells, first of all responsible for development of these forms of the immune answer. The actual problem of modern transplantology is working out of methods which would promote accumulation in an organism of recipient T-regulatory of cells with suppressive properties for formation the donor-specific immune tolerance into recipient`s organism.
About the Authors
S. D. Artamonov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
N. A. Onishchenko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
L. V. Bashkina
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
V. S. Suskova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
M. E. Krasheninnikov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
A. O. Nikol’skaya
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
D. A. Velikiy
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Artamonov S.D., Onishchenko N.A., Bashkina L.V., Suskova V.S., Krasheninnikov M.E., Nikol’skaya A.O., Velikiy D.A. I. ROLE OF THE INNATE AND ADAPTIVE IMMUNITY FOR A DEVELOPMENT OF DESTRUCTIVE IMMUNE RESPONSE OF ORGANISM ON ALLOGRAFT. Russian Journal of Transplantology and Artificial Organs. 2010;12(3):112-120. (In Russ.) https://doi.org/10.15825/1995-1191-2010-3-112-120
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