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Вестник трансплантологии и искусственных органов

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ОСТРОЕ ПОВРЕЖДЕНИЕ ПОЧЕК ПРИ КАРДИОХИРУРГИЧЕСКИХ ОПЕРАЦИЯХ С ИСКУССТВЕННЫМ КРОВООБРАЩЕНИЕМ И ТРАНСПЛАНТАЦИИ СЕРДЦА

https://doi.org/10.15825/1995-1191-2010-1-100-110

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Аннотация

Острое повреждение почек (ОПП) развивается в среднем у 30% больных при операциях с искусственным кровообращением (ИК). При этом заместительная почечная терапия (ЗПТ) применяется, по разным данным, у 1–3,3% всех оперированных пациентов. В патогенезе ОПП при операциях с ИК имеют значение гемодинамические, воспалительные и нефротоксические факторы. Многочисленные клинические исследования позволили выявить предикторы развития ОПП в этой категории больных. Данных о риске и последствиях ОПП у пациентов при трансплантации сердца в литературе значительно меньше. В этих случаях помимо прочих факторов имеет значение и нефротоксическое действие иммуносупрессивных препаратов. 

Об авторах

Ю. В. Копылова
ФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова» Минздравсоцразвития РФ, Москва
Россия


Я. Л. Поз
ФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова» Минздравсоцразвития РФ, Москва
Россия


А. Г. Строков
ФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова» Минздравсоцразвития РФ, Москва
Россия


В. Н. Попцов
ФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова» Минздравсоцразвития РФ, Москва
Россия


О. В. Воронина
ФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова» Минздравсоцразвития РФ, Москва
Россия


С. Г. Ухренков
ФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова» Минздравсоцразвития РФ, Москва
Россия


Список литературы

1. Ostermann M., Taube D., Morgan C.J., Evans T.W. Acute renal failure following cardiopulmonary bypass: a changing picture // Intensive Care Med. 2000. Vol. 26. Р. 565–571.

2. Antunes P.E., Prieto D., Ferrao de Oliveira J., Antu- nes M.J. Renal dysfunction alter myocardial revas- cularization // Eur. J. Cardiothorac. Surg. 2004. Vol. 25. Р. 597–604.

3. Mangano C.M., Diamondstone L.S., Ramsay J.G. et al. Renal dysfunction after myocardial revascular- ization: risk factors, adverse outcomes and hospital resource utilization // Ann Intern. Med. 1998. Vol. 128. Р. 194–203.

4. Chertow G.M., Levy E.M., Hammermeister K.E. et al. Independent association between acute renal failure and

5. mortality following cardiac surgery // Am. J. Med. 1998.

6. Vol. 104. Р. 343–348.

7. Conlon P.J., Stafford-Smith M., White W.D. et al.

8. Acute renal failure following cardiac surgery // Neph-

9. rol. Dial. Transplant. 1999. Vol. 14. Р. 1158–1162.

10. Abraham V.S., Swain J.A. Cardiopulmonary bypass and the kidney // Gravlee G.P., Davis R.F., Kurusz M., Ut- ley J.R., eds. Cardiopulmonary Bypass: Principles and Practice. 2nd ed. Philadelphia: Lippincott, Williams &

11. Wilkins. 2000. Р. 382–391.

12. Grayson A.D., Khater M., Jackson M., Fox M.A. Valvu-

13. lar heart operation is an independent risk factor for acute renal failure // Ann Thorac. Surg. 2003. Vol. 75. Р. 1829– 1835.

14. Lassnigg A., Schmidlin D., Mouhieddine M. et al. Mini- mal changes of serum creatinine predict prognosis in pa- tients after cardiothoracic surgery: a prospective cohort study // J. Am. Soc. Nephrol. 2004. Vol. 15. Р. 1597– 1605.

15. Thakar C.V., Worley S., Arrigain S. Influence of renal dysfunction on mortality after cardiac surgery: modify- ing effect of preoperative renal function // Kidney Int. 2005. Vol. 67. Р. 1112–1119.

16. Loef B.G., Epema A.H., Smilde T.B. et al. Immediate post- operative renal function deterioration in cardiac surgical patients predicts in-hospital mortality and long-term sur- vival // J. Am. Soc. Nephrol. 2005. Vol. 16. Р. 195–200.

17. Lok C.E., Austin P.C., Wanh H., Tu J.V. Impact of renal insufficiency on short- and long-term outcomes after car- diac surgery // Am. Heart J. 2004. Vol. 148. Р. 430–438.

18. Liano F., Pascual J. Epidemiology of acute renal fail- ure: a prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group // Kidney Int. 1996. Vol. 50. Р. 811–818.

19. Thakar C.V., Yared J.-P., Worley S. Renal dysfunction and serious infections after open-heart surgery // Kidney Int. 2003. Vol. 64. Р. 239–246.

20. Thakar C.V., Liangos O., Yared J.-P. et al. Predicting acute renal failure after cardiac surgery: validation and re-definition of a risk stratification algorithm // Hemo- dial. Int. 2003. Vol. 7. Р. 143–147.

21. Thakar C.V., Arrigain S., Worley S. et al. A clinical score to predict acute renal failure after cardiac surgery // J. Am. Soc. Nephrol. 2005. Vol. 16. Р. 162–168.

22. Fortescue E.B., Bates D.W., Chertow G.M. Predicting acute renal failure after coronary bypass surgery: cross- validation of two risk-stratification algorithms // Kidney Int. 2000. Vol. 57. Р. 2594–2602.

23. Thakar C.V., Liangos O., Yared J.-P. et al. ARF after open-heart surgery: influence of gender and race // Am. J. Kidney Dis. 2003. Vol. 41. Р. 742–751.

24. Fischer U.M., Weissenberger W.K., Warters R.D. et al. Impact of cardiopulmonary bypass management on post- cardiac surgery renal function // Perfusion. 2002. Vol. 17. Р. 401–406.

25. Tuttle K.R., Worrall N.K., Dahlstrom LR. et al. Predic- tors of ARF after cardiac surgical procedures // Am. J. Kidney Dis. 2003. Vol. 41. Р. 76–83.

26. Abramov D., Tamariz M., Serrick C.I. et a1. The influ- ence of cardiopulmonary bypass flow characteristics on the clinical outcome of 1820 coronary bypass patients //

27. Can. J. Cardiol. 2003. Vol. 19. Р. 237–243.

28. Provenchere S., Plantefeve G., Hufnagel G. et al. Re- nal dysfunction after cardiac surgery with normothermic cardiopulmonary bypass: incidence, risk factors and ef- fect on clinical outcome // Anesth. Analg. 2003. Vol. 96.

29. Р. 1258–1264.

30. Cook D.J. Changing temperature management for car-

31. diopulmonary bypass // Anesth. Analg. 1999. Vol. 88.

32. Р. 1254–1271.

33. Schwann N.M., Horrow J.C., Strong M.D. Does off-

34. pump coronary artery bypass reduce the incidence of clinically evident renal dysfunction after multivessel myocardial revascularization? // Anesth. Analg. 2004. Vol. 99. Р. 959–964.

35. Stallwood M.I., Grayson A.D., Mills K., Scawn N.D. Acute renal failure in coronary artery bypass surgery: independent effect of cardiopulmonary bypass // Ann Thorac. Surg. 2004. Vol. 77. Р. 968–972.

36. Loef B.G., Epema A.H., Navis G. et al. Off-pump coro- nary revascularization attenuates transient renal damage compared with on-pump coronary revascularization // Chest. 2002. Vol. 121. Р. 1190–1194.

37. Wijeysundera D.N., Beattie W.S., Djaiana G. et al. Off- pump coronary artery surgery for reducing mortality and morbidity: meta-analysis of randomized and observatio- nal studies // J. Am. Coll. Cardiol. 2005. Vol. 46. Р. 872– 882.

38. Hix J.K., Thakar C.V., Katz E.M. et al. Effect of off- pump coronary artery bypass graft surgery on postopera- tive acute kidney injury and mortality // Crit. Care Med. 2006. Vol. 34. Р. 2979–2983.

39. Vermeer H., Teerenstra S., de Sévaux R.G. et al. The ef- fect of hemodilution during normothermic cardiac sur- gery on renal physiology and function: a review // Perfu- sion. 2008. Vol. 23 (6). Р. 329–338.

40. Huybregts R.A., de Vroege R., Jansen E.K. et al. The as- sociation of hemodilution and transfusion of red blood cells with biochemical markers of splanchnic and renal injury during cardiopulmonary bypass // Anesth. Analg. 2009. Vol. 109 (2). Р. 331–339.

41. Swaminathan M., Phillips-Bute B.G., Conlon P.J. et al. The association of lowest hematocrit during cardiopul- monary bypass with acute renal injury after coronary ar- tery bypass surgery // Ann Thorac. Surg. 2003. Vol. 76. Р. 784–792.

42. Karkouti K., Beattie W.S., Wijeysundera D.N. et al. He- modilution during cardiopulmonary bypass is an inde- pendent risk factor for acute renal failure in adult cardiac surgery // J. Thorac. Cardiovasc. Surg. 2005. Vol. 129. Р. 391–400.

43. Sheridan A.M., Bonventre J.V. Cell biology and mo- lecular mechanisms of injury in ischemic acute renal failure // Curr. Opin. Nephrol. Hypertens. 2000. Vol. 9. Р. 427–434.

44. Sutton T.A., Fisher C.J., Molitoris B.A. Microvascular endothelial injury and dysfunction during ischemic acute renal failure // Kidney Int. 2002. Vol. 62. Р. 1539–1549.

45. Okusa M.D. The inflammatory cascade in acute ischemic renal failure // Nephron. 2002. Vol. 90. Р. 133–138.

46. Evans R.G., Eppel G.A., Anderson W.P., Denton K.M.

47. Mechanisms underlying the differential control of blood flow in the renal medulla and cortex // J. Hypertens. 2004. Vol. 22 (8). Р. 1439–1451.

48. Bennet-Guerrero E., Ayuso L., Hamilton-Davies C. et al. Relationship of pre-operative anti-endotoxin core antibodies and adverse outcomes following cardiac sur- gery // JAMA. 1997. Vol. 277. Р. 646–650.

49. Lequier L.L., Nikaidoh H., Leonard S.R. et al. Preopera- tive and postoperative endotoxemia in children with con- genital heart disease // Chest. 2000. Vol. 117. Р. 1706– 1712.

50. Riddington D.W., Venkatesh B., Boivin C.M. et al. Intes- tinal permeability, gastric intramucosal pH, and systemic endotoxemia in patients undergoing cardiopulmonary bypass // JAMA. 1996. Vol. 275. Р. 1007–1012.

51. Torre-Amione G., Kapadia S., Benedict C. et al. Proin- flammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the stud- ies of left ventricular dysfunction (SOLVD) // J. Am. Coll Cardiol. 1996. Vol. 27. Р. 1201–1206.

52. Parolari A., Alamanni F., Gherli T. et al. Cardiopulmo- nary bypass and oxygen consumption: oxygen delivery and hemodynamics // Ann Thorac. Surg. 1999. Vol. 67. Р. 1320–1327.

53. Kurusz M., Davis R.F., Conti V.R. Conduct of cardiopul- monary bypass // Gravlee G.P., Davis R.F., Kurusz M., Utley J.R., eds. Cardiopulmonary Bypass: Principles and Practice. 2nd ed. Philadelphia: Lippincott, Williams & Wilkins. 2000. Р. 549–578.

54. Gold J.P., Charlson M.E., Williams-Russo P. et al. Im- provement of outcomes after coronary artery bypass: a randomized trial comparing intraoperative high versus low mean arterial pressure // J. Thorac. Cardiovasc. Surg. 1995. Vol. 110. Р. 1302–1314.

55. Kelleher S.P., Robinette J.B., Conger J.D. Sympathetic nervous system in the loss of autoregulation in acute renal failure // Am. J. Physiol. 1984. Vol. 246. Р. F379– F386.

56. Taylor K. SIRS: the systemic inflammatory response syndrome after cardiac operations // Ann Thorac. Surg. 1996. Vol. 61. Р. 1607–1608.

57. Czerny M., Baumer H., Kilo J. et al. Inflammatory re- sponse and myocardial injury following coronary artery bypass grafting with or without cardiopulmonary by- pass // Eur. J. Cardiothorac. Surg. 2000. Vol. 17. Р. 737–

58. Habib R.H., Zacharias A., Schwann T.A. et al. Role of hemodilutional anemia and transfusion during cardio-

59. pulmonary bypass in renal injury after coronary revas- cularization: implications on operative outcome // Crit

60. Care Med. 2005. Vol. 33. Р. 1749–1756. 742.

61. Eriksen B.O., Hoff K.R.S., Solberg S. Prediction of acute renal failure after cardiac surgery: retrospective cross- validation of a clinical algorithm // Nephrol. Dial. Trans- plant. 2003. Vol. 18. Р. 77–81.

62. Galinanes M., Watson C., Trivedi U. et al. Differential patterns of neutrophil adhesion molecules during car- diopulmonary bypass in humans // Circulation. 1996. Vol. 94 (suppl 2). Р. 364–369.

63. Asimakopoulos G., Taylor K.M. Effects of cardiopulmo- nary bypass on leukocyte and endothelial adhesion mole- cules // Ann Thorac. Surg. 1998. Vol. 66. Р. 2135–2144.

64. Bonventre J.V. Pathophysiology of acute kidney injury: roles of potential inhibitors of inflammation // Contrib. Nephrol. 2007. Vol. 156. Р. 39–46.

65. Paparella D., Brister S.J., Buchanan M.R. Coagulation disorders of cardiopulmonary bypass: a review // Inten- sive Care Med. 2004. Vol. 30 (10). Р. 1873–1881.

66. Haga Y., Hatori N., Yoshizu H. et al. Granulocyte super- oxide anion and elastase release during cardiopulmonary bypass // Artif. Organs. 1993. Vol. 17. Р. 837–842.

67. Faymonville M.E., Pincemail J., Duchateau J. et al. Myeloperoxidase and elastase as markers of leukocyte activation during cardiopulmonary bypass // J. Thorac. Cardiovasc. Surg. 1991. Vol. 102. Р. 309–317.

68. Frering B., Philip I., Dehous M. et a1. Circulating cy- tokines in patients undergoing normothermic cardio- pulmonary bypass // J. Thorac. Cardiovasc. Surg. 1994. Vol. 108. Р. 642–647.

69. Paparella D., Yau T.M., Young E. Cardiopulmonary by- pass induced inflammation: pathophysiology and treat- ment: an update // Eur. J. Cardiothorac. Surg. 2002. Vol. 21. Р. 232–244.

70. Rosner M., Okusa M. Acute kidney injury associated with cardiac surgery // Clin. J. Am. Soc. Nephrol. 2006. Vol. 1. Р. 19–32.

71. Cremer J., Martin M., Redl H. et al. Systemic inflam- matory response after cardiac operations // Ann Thorac. Surg. 1996. Vol. 61. Р. 1714–1720.

72. Hornick P., Taylor K.M. Immune and inflammatory re- sponses after cardiopulmonary bypass // Gravlee G.P., Davis R.F., Kurusz M., Utley J.R., eds. Cardiopulmonary Bypass: Principles and Practice. 2nd ed. Philadelphia: Lippincott, Williams & Wilkins. 2000. Р. 303–320.

73. Campbell D.J., Dixon B., Kladis A. et al. Activation of the kallikrein-kinin system by cardiopulmonary bypass in humans // Am. J. Physiol. Regul lntegr. Comp. Physi- ol. 2001. Vol. 281. Р. R1059–Rl070.

74. Moreau M.E., Garbacki N., Molinaro G. et al. The kal- likrein-kinin system: current and future pharmacological targets // J. Pharmacol. Sci. 2005. Vol. 99. Р. 6–38.

75. Marcheix B., Carrier M., Martel C. et al. Effect of pe- ricardial blood processing on postoperative inflamma- tion and the complement pathways // Ann Thorac. Surg. 2008. Vol. 85 (2). Р. 530–535.

76. Donnahoo K.K., Meng X., Ayala A. et al. Early kidney TNF-expression mediates neutrophil infiltration and in- jury after renal ischemia-reperfusion // Am. J. Physiol. 1999. Vol. 277. Р. R922–R929.

77. Burne-Taney M.J., Rabb H. The role of adhesion mo- lecules and T-cells in ischemic renal injury // Curr Opin Nephrol. Hypertens. 2003. Vol. 12. Р. 85–90.

78. Groom R.C. A systematic approach to the understan- ding and redesigning of cardiopulmonary bypass// Semin Cardiothorac. Vasc. Anesth. 2005. Vol. 9 (2). Р. 159–161.

79. Blauth J. Macroemboli and microemboli during cardio- pulmonary bypass // Ann Thorac. Surg. 1995. Vol. 59. Р. 1300–1303.

80. Sreeram G.M., Grocott H.P., White W.D. et al. Transcra- nial Doppler emboli count predicts rise in creatinine af- ter coronary artery bypass graft surgery // J. Cardiovasc. Vasc. Anesth. 2004. Vol. 18. Р. 548–551.

81. Bidstrup B.P., Royston D., Sapsford R.N. et al. Reduc- tion in blood loss and blood use after cardiopulmonary bypass with high-dose aprotinin // J. Thorac. Cardiovasc. Surg. 1989. Vol. 97. Р. 364–372.

82. Runstom R., Grime J.S., Maltby P. et al. Observations on the early renal uptake and later tubular metabolism of radiolabeled aprotinin (Trasylol) in man: theoretical and practical considerations // Clin. Sci (Colch). 1993. Vol. 84. Р. 231–241.

83. Mangano D.T., Tudor I.C., Dietzel C. The risk associated with aprotinin in cardiac surgery // N Engl. J. Med. 2006. Vol. 354. Р. 353–365.

84. Kincaid E.H., Ashburn D.A., Hoyle J.R. et al. Does the combination of aprotinin and angiotensin-converting enzyme inhibitor cause renal failure after cardiac sur- gery? // Ann Thorac. Surg. 2005. Vol. 80. Р. 1388–1393.

85. Kristeller J.L., Roslund B.P., Stahl R.F. Benefits and risks of aprotinin use during cardiac surgery // Pharma- cotherapy. 2008; 28 (1). Р. 112–124.

86. Ambrus C.M., Lajos T.Z., Stadler I. et al. Myocardial release of non-transferrin-bound iron during cardio-pul- monary bypass surgery // J. Med. 1999. Vol. 30 (3–4). Р. 157–167.

87. Haase M., Haase-Fielitz A., Bagshaw S.M. et al. Cardio- pulmonary bypass-associated acute kidney injury: a pig- ment nephropathy? // Contrib. Nephrol. 2007. Vol. 156. Р. 340–353.

88. Paraskevaidis I.A., Iliodromitis E.K., Vlahakos D. et al. Deferoxamine infusion during coronary artery bypass grafting ameliorates lipid peroxidation and protects the myocardium against reperfusion injury: immediate and long-term significance // Eur. Heart J. 2005. Vol. 26 (3). Р. 263–270.

89. Ponticelli C. Medical complications of kidney transplan- tation // Informa UK. 2007. P. 125–127.

90. Greenberg A., Egel J., Thompson M. et al. Early and late forms of cyclosporine nephrotoxicity: studies in cardiac transplant patients // Am. J. Kidney Dis. 1987. Vol. 9. Р. 12–22.

91. McGiffin D., Kirklin J., Naftel D. Acute renal failure af- ter heart transplantation and cyclosporine therapy // J. Heart Transplant. 1985. Vol. 4. Р. 396–399.

92. Stevens L-M., El-Hamamsy I., Leblanc M. et al. Conti- nuous renal replacement therapy after heart transplan- tation // Can. J. Cardiol. 2004. Vol. 20 (6). Р. 619–623.

93. Cipullo R., Finger M., Ponce F. et al. Renal Failure as a Determinant of Mortality After Cardiac Transplanta- tion // Transplant Proc. 2004. Vol. 36. Р. 989–990.

94. Zarragoikoetxea Jauregui I., Aguero Ramon-Llin J., Al- menar Bonet L. et al. Major complications in the recov- ery unit following heart transplant: incidence and risk factors // Rev Esp. Anestesiol. Reanim. 2008. Vol. 55 (9). Р. 535–540.

95. Moualla S., Boyle J., Arrigain S. et al. Increased mor- tality with post-operative renal failure after cardiac transplant // J. Heart Lung Transplant. 2006. Vol. 25 (2) Suppl 1. Р. S57.

96. Sezgin A., Akay T., Gultekin B. et al. The impact of renal failure on survival following cardiac transplantation // Transplant Proc. 2007. Vol. 37 (4). Р. 1247–1249.

97. Boyle J., Moualla S., Arrigain S. et al. Risks and Out- comes of Acute Kidney Injury Requring Dialysis After Cardiac Transplantation // Am. J. Kidney Dis. 2006. Vol. 48 (5). Р. 787–796.

98. Al Aly Ziyad, Abbas S., Moore E. et al. The natural history of renal function following orthotopic heart

99. Cruz D., Perazella M. Acute Renal Failure after Cardiac Transplantation: A Case Report and Review of the Lite- rature // Yale J. of Biology and Medicine. 1996. Vol. 69. Р. 461–468.

100. Ouseph R., Brier M., Jacobs A., Erbeck K. Continuous venovenous hemofiltration and hemodialysis after ortho- topic heart transplantation // Am. J. Kidney Dis. 1998. Vol. 32 (2). Р. 290–294.

101. OdimJ.,WheatJ.,LaksH.etal.Peri-operativerenalfunc- tion and outcome after orthotopic heart transplantation // J. Heart Lung Transplant. 2006. Vol. 25 (2). Р. 162–166.


Для цитирования:


Копылова Ю.В., Поз Я.Л., Строков А.Г., Попцов В.Н., Воронина О.В., Ухренков С.Г. ОСТРОЕ ПОВРЕЖДЕНИЕ ПОЧЕК ПРИ КАРДИОХИРУРГИЧЕСКИХ ОПЕРАЦИЯХ С ИСКУССТВЕННЫМ КРОВООБРАЩЕНИЕМ И ТРАНСПЛАНТАЦИИ СЕРДЦА. Вестник трансплантологии и искусственных органов. 2010;12(1):100-110. https://doi.org/10.15825/1995-1191-2010-1-100-110

For citation:


Kopylova J.V., Poz Y.L., Strokov A.G., Poptsov V.N., Voronina O.V., Uhrenkov S.G. ACUTE KIDNEY INJURY AFTER CARDIAC SURGERY WITH CARDIOPULMONARY BYPASS AND HEART TRANSPLANTATION. Russian Journal of Transplantology and Artificial Organs. 2010;12(1):100-110. (In Russ.) https://doi.org/10.15825/1995-1191-2010-1-100-110

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