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Fluorescence-guided laparoscopic living-donor hepatectomy to acquire an S2 graft

https://doi.org/10.15825/1995-1191-2025-1-32-39

Abstract

Background. Liver transplantation (LT) in children with low body weight using the left lateral segment from a living donor is associated with large-for-size syndrome (LFSS). We present the first Russian clinical case of laparoscopic living-donor hepatectomy to acquire an S2 graft. Materials and methods. A six-month-old child who had biliary atresia-induced liver cirrhosis was prepared for transplantation. The child’s 20-year-old mother was the donor. The left lateral segment had a volume of 426 mL (graft-to-recipient weight ratio, GRWR, was 5.9%). Indocyanine green fluorescence-guided laparoscopic intracorporeal reduction up to the S2 segment was performed. Results. Donor operation time was 230 minutes, blood loss was 50 ml. The postoperative period was uneventful; the donor was discharged on day 9. The recipient had no surgical complications; a rejection episode was successfully managed. The child was discharged with a satisfactory graft function. Discussion. Fluorescenceguided laparoscopic living-donor hepatectomy to acquire an S2 graft is effective and safe. The presented technique may be an effective solution when performing monosegmental LT under the high-risk conditions of LFSS.

About the Authors

A. R. Monakhov
Shumakov National Medical Research Center of Transplantology and Artificial Organs ; Sechenov University
Russian Federation

Artem Monakhov 

1, Shchukinskaya str., Moscow, 123182   Phone: (906) 078-16-21 



V. R. Salimov
Shumakov National Medical Research Center of Transplantology and Artificial Organs
Russian Federation

Moscow



S. V. Meshcheryakov
Shumakov National Medical Research Center of Transplantology and Artificial Organs
Russian Federation

Moscow 



I. I. Kurbanov
Sechenov University
Russian Federation

Moscow 



D. I. Bystrov
Volzhsky Branch of Shumakov National Medical Research Center of Transplantology and Artificial Organs
Russian Federation

Volzhsky



S. V. Gautier
Shumakov National Medical Research Center of Transplantology and Artificial Organs ; Sechenov University
Russian Federation

Moscow 



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Monakhov A.R., Salimov V.R., Meshcheryakov S.V., Kurbanov I.I., Bystrov D.I., Gautier S.V. Fluorescence-guided laparoscopic living-donor hepatectomy to acquire an S2 graft. Russian Journal of Transplantology and Artificial Organs. 2025;27(1):32-39. https://doi.org/10.15825/1995-1191-2025-1-32-39

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ISSN 1995-1191 (Print)