HBV-INFECTION DE NOVO AFTER ORTHOTOPIC LIVER TRANSPLANTATION: CLINICAL AND VIROLOGICAL CHARACTERISTICS, ASSESSMENT OF ANTIVIRUS THERAPY EFFECTIVENESS
https://doi.org/10.15825/1995-1191-2012-3-24-30
Abstract
We studied 11 cases of HBV-infection de novo in patients after orthotopic liver transplantation performed because of non-viral cirrhosis. Serum НBeAg, was revedled in all patients. In most cases clinical course of HBV-infection was benign. Treatment with entecavir was more effective than lamivudin, and brought to НBsAg elimination in 4 patients. Treatment with lamivudin led to descrease viral load in all patients and HBsAg elimination in one case.
About the Authors
O. I. Malomuzh
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
E. V. Chekletsova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
X. M. Кhizroyev
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
V. A. Pets
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
S. V. Fokin
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
V. A. Taranov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
O. M. Tsirulniкova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
S. V. Gautier
ФГБУ «ФНЦ трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России, г. Москва
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Review
For citations:
Malomuzh O.I., Chekletsova E.V., Кhizroyev X.M., Pets V.A., Fokin S.V., Taranov V.A., Tsirulniкova O.M., Gautier S.V. HBV-INFECTION DE NOVO AFTER ORTHOTOPIC LIVER TRANSPLANTATION: CLINICAL AND VIROLOGICAL CHARACTERISTICS, ASSESSMENT OF ANTIVIRUS THERAPY EFFECTIVENESS. Russian Journal of Transplantology and Artificial Organs. 2012;14(3):24-30. (In Russ.) https://doi.org/10.15825/1995-1191-2012-3-24-30
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