Биодеградируемые изделия из натурального шелка для регенеративной медицины
https://doi.org/10.15825/1995-1191-2024-4-157-165
Аннотация
Шелк благодаря своим уникальным физико-химическим и биологическим свойствам становится одним из ключевых материалов в современной биоинженерии и медицине. В данной обзорной статье обсуждаются основные компоненты шелка – фиброин и серицин, их структура и функциональные характеристики, а также их значение для создания биосовместимых и биодеградируемых материалов. Рассматриваются современные подходы к модификации шелка, включая физическую, химическую и генетическую модификацию, с целью улучшения его механических и биологических свойств. Особое внимание уделено применению шелка в тканевой инженерии, разработке медицинских имплантатов, систем контролируемой доставки лекарств и биосенсоров. В заключение обсуждаются перспективы дальнейших исследований шелка, направленных на создание инновационных биоматериалов для медицинских применений.
Об авторах
Е. И. Подболотова
ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России
Россия
Россия
Москва
О. И. Агапова
ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России
Россия
Россия
Агапова Ольга Игоревна
123182, Москва, ул. Пехотная, д. 5.
Тел. (499) 190-66-19
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Рецензия
Для цитирования:
Подболотова Е.И., Агапова О.И. Биодеградируемые изделия из натурального шелка для регенеративной медицины. Вестник трансплантологии и искусственных органов. 2024;26(4):157-165. https://doi.org/10.15825/1995-1191-2024-4-157-165
For citation:
Podbolotova E.I., Agapova O.I. Biodegradable silk-based products for regenerative medicine. Russian Journal of Transplantology and Artificial Organs. 2024;26(4):157-165. https://doi.org/10.15825/1995-1191-2024-4-157-165
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