SIMULTANEOUS PANCREAS-KIDNEY TRANSPLANTATION: EARLY POSTOPERATIVE COMPLICATIONS
https://doi.org/10.15825/1995-1191-2014-2-24-29
Abstract
Aim: evaluation of the incidence of early postoperative complications after simultaneous pancreas-kidney transplantation.
Materials and methods. The analysis of early postoperative complications after simultaneous pancreas-kidney transplantation is presented in the paper, the most rational diagnostic algorithms, non-surgical and surgical complications’ treatment; the outcomes of the SPKT are reported.
Results. 15,6% of patients experienced surgical complications, 12,5% – immunological complications, 12,5% – infectious complications, 6,25% – complications of the immunosuppressive therapy. 1-year patient survival after SPKT was 91,4%; pancreas graft survival – 85,7%; kidney graft survival – 88,6%.
Conclusion. The incidence of early postoperative complications after simultaneous pancreas-kidney transplantation remains signifi cant in spite of progressive improvement of simultaneous pancreas-kidney transplantation due to surgical technique improvement, introduction of new antibacterial and immunosuppressive agents. Data, we recovered, fully correspond to the data obtained from the global medical community.
About the Authors
M.Sh. Khubutia
Department of kidney and pancreas transplantation, State-fi nanced health institution N.V. Sklifosovsky Scientifi c Research Institute of Emergency Care, Moscow City Health Department, Moscow, Russian Federation
Russian Federation
Russian Federation
A.V Pinchuk
Department of kidney and pancreas transplantation, State-fi nanced health institution N.V. Sklifosovsky Scientifi c Research Institute of Emergency Care, Moscow City Health Department, Moscow, Russian Federation
Russian Federation
Russian Federation
I.V. Dmitriev
Department of kidney and pancreas transplantation, State-fi nanced health institution N.V. Sklifosovsky Scientifi c Research Institute of Emergency Care, Moscow City Health Department, Moscow, Russian Federation
Russian Federation
Russian Federation
K.E. Lazareva
Department of kidney and pancreas transplantation, State-fi nanced health institution N.V. Sklifosovsky Scientifi c Research Institute of Emergency Care, Moscow City Health Department, Moscow, Russian Federation
Russian Federation
Russian Federation
A.G. Balkarov
Department of kidney and pancreas transplantation, State-fi nanced health institution N.V. Sklifosovsky Scientifi c Research Institute of Emergency Care, Moscow City Health Department, Moscow, Russian Federation
Russian Federation
Russian Federation
R.V. Storozhev
Department of kidney and pancreas transplantation, State-fi nanced health institution N.V. Sklifosovsky Scientifi c Research Institute of Emergency Care, Moscow City Health Department, Moscow, Russian Federation
Russian Federation
Russian Federation
N.V. Shmarina
Department of kidney and pancreas transplantation, State-fi nanced health institution N.V. Sklifosovsky Scientifi c Research Institute of Emergency Care, Moscow City Health Department, Moscow, Russian Federation
Russian Federation
Russian Federation
References
1. Humar A., Kandaswamy R., Granger D., Gruessner R.W., Gruessner A.C., Sutherland D.E. Decreased surgical risks of pancreas transplantation in the modern era. Ann Surg. 2000; 231 (2): 269–275.
2. Gruessner R.W.G., Sutherland D.E.R. (eds). Transplantation of the pancreas. New York: Springer, 2004: 39–69, 111–267.
3. Corry R.J., Shapiro R. (eds.). Pancreatic Transplantation. New York: Informa Healthcare, 2007: 131–134.
4. Hakim N.S., Stratta R.J., Gray D., Friend P., Coleman A. (eds). Pancreas, islet, and stem cell transplantation for diabetes. 2nd ed. Oxford university press. 2010: 179–189.
5. Martins L., Henriques A.C., Dias L., Almeida M., Pedroso S., Freitas C. et al. Pancreas-kidney transplantation: complications and readmissions in 9-years of follow-up. Transplant Proc. 2010; 42 (2): 552–554. doi: 10.1016/j.transproceed.2010.01.043.
6. Grochowiecki T., Gałazka Z., Frunze S., Nazarewski S., Jakimowicz T., Paczek L. et al. Infl uence of simultaneous pancreas and preemptive kidney transplantation on severity of postoperative complications. Transplant Proc. 2011; 43 (8): 3102–3104. doi: 10.1016/j.transproceed. 2011.08.029.
7. Steurer W., Malaise J., Mark W., Koenigsrainer A., Margreiter R. Spectrum of surgical complications after simultaneous pancreas-kidney transplantation in a prospectively randomized study of two immunosuppressive protocols. Nephrol Dial Transplant. 2005; 20 Suppl 2: ii54–62.
Review
For citations:
Khubutia M., Pinchuk A., Dmitriev I., Lazareva K., Balkarov A., Storozhev R., Shmarina N. SIMULTANEOUS PANCREAS-KIDNEY TRANSPLANTATION: EARLY POSTOPERATIVE COMPLICATIONS. Russian Journal of Transplantology and Artificial Organs. 2014;16(2):24-29. (In Russ.) https://doi.org/10.15825/1995-1191-2014-2-24-29
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