Heart transplantation waiting list of V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs. Trends from 2010 to 2017

The aim: to analyze the waiting list for heart transplantation from 2010 to 2017 and to characterize recipients with chronic heart failure III–IV NYHA Class.

Methods. The study comprised 997 patients (139 [14%] females and 858 [86%] males) included in the waiting list for heart transplantation the period from January 2010 to December 2017. The average age of patients on the waiting list was 49.0 ± 12.0 (from 10 to 78 years). Before making a decision on inclusion in the waiting list, all patients underwent clinical and instrumental examination, including general clinical studies, echocardiography, measurement of central hemodynamic parameters using a Swan–Gans catheter, computer and/or magnetic resonance imaging of the chest, abdominal and brain.

Results. Heart transplantation was performed on 728 patients (99 females – 13.6% and 629 males – 86.4%) including 18 children aged 12 to 17 years (14.18 ± 2.07 years). Mortality in the waiting list in 2010 was 16.1%, compared with 3.2% in 2017.

1. Трансплантология: итоги и перспективы. Том IX. 2017 год. Под ред. С.В. Готье. М.–Тверь: Триада, 2018: 36–43. Transplantologiya: itogi i perspektivy. Tom IX. 2017 god. Pod red. S.V. Gautier. M.–Tver’: Triada, 2018: 36–43.

2. Yusen RD, Christie JD, Edwards LB et al.The Registry of the International Society for Heart and Lung Transplantation: Thirtieth Adult Lung and Heart-Lung Transplant Report – 2013; focus theme: age. J Heart Lung Transplant.2013; 32: 965–978.

3. Ciarka A, Edwards L, Nilsson J, Stehlik J, Lund LH. Trends in the use of mechanical circulatory support as a bridge to heart transplantation across different age groups. Int J Cardiol.2017; 231: 225–227.

4. Mehra MR, Canter CE, Hannan MM, Semigran MJ et al.The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: A 10-year update. The Journal of Heart and Lung Transplantation. 2016; (35): 1–23.

5. Lund LH, Edwards LB, Kucheryavaya AY et al. The Registry of the International Society for Heart and Lung Transplantation: Thirty-second Official Adult Heart Transplantation Report – 2015; Focus Theme: Early Graft Failure. J Heart Lung Transplant.2015; 34: 1244– 1254.

6. Lund LH, Edwards LB, Kucheryavaya AY, Benden C, Christie JD, Dipchand AI. The registry of the International Society for Heart and Lung Transplantation: thirty-first official adult heart transplant report – 2014; focus theme: retransplantation. J Heart Lung Transplant. 2014; 33 (10): 996–1008.

7. Rossano JW, Dipchand AI, Edwards LB et al.The Registry of the International Society for Heart and Lung Transplantation: Nineteenth Pediatric Heart Transplantation Report – 2016; Focus Theme: Primary Diagnostic Indications for Transplant. J Heart Lung Transplant. 2016; 35: 1185–1195.

8. Decline in Heart Transplant Wait List Mortality in the United States Following Broader Regional Sharing of Donor Hearts Tajinder P. Singh, MD, MSc; Christopher S. Almond, MD, MPH; David O. Taylor, MD; Dionne A. Graham, PhD (Circ Heart Fail. 2012; 5: 249–258.)

9. Kittleson MM, Kobashigawa JA. Management of Advanced Heart Failure The Role of Heart Transplantation. Circulation. 2011; 123 (14): 1572.