ИНФОРМАЦИОННАЯ ЗНАЧИМОСТЬ МОНИТОРИНГА ПОПУЛЯЦИЙ СD4+ Т-ЛИМФОЦИТОВ В ДИАГНОСТИКЕ И ПРОГНОЗИРОВАНИИ РЕАКЦИИ ОРГАНИЗМА НА ТРАНСПЛАНТАТ
https://doi.org/10.15825/1995-1191-2013-4-112-125
Аннотация
В обзоре обосновывается необходимость внедрения в клиническую практику комплексного мониторинга иммунных клеток крови и цитокинов у больных с пересаженными органами для выбора индивидуальной тактики иммуносупрессивной терапии, оценки ее эффективности и прогнозирования результатов. Подчеркивается, что с особым вниманием следует отнестись к характеристике CD4+ T-лимфоцитов и определению соотношения их отдельных популяций в периферической крови (Treg, Th17, Tact клетки памяти CD4+CD25hiCD127hiCD45RO), так как именно они являются основными участниками ответа иммунной системы организма на трансплантат.
Об авторах
Н. А. ОнищенкоЛ. В. Башкина
А. О. Никольская
С. Д. Артамонов
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Рецензия
Для цитирования:
Онищенко Н.А., Башкина Л.В., Никольская А.О., Артамонов С.Д. ИНФОРМАЦИОННАЯ ЗНАЧИМОСТЬ МОНИТОРИНГА ПОПУЛЯЦИЙ СD4+ Т-ЛИМФОЦИТОВ В ДИАГНОСТИКЕ И ПРОГНОЗИРОВАНИИ РЕАКЦИИ ОРГАНИЗМА НА ТРАНСПЛАНТАТ. Вестник трансплантологии и искусственных органов. 2013;15(4):112-125. https://doi.org/10.15825/1995-1191-2013-4-112-125
For citation:
Onishchenko N.A., Bashkina L.V., Nicolskaya A.O., Artamonov S.D. SIGNIFICANCE OF СD4+ Т-LYMPHOCYTE POPULATIONS MONITORING FOR DIAGNOSING AND FORECASTING OF ORGANISM REACTION ON TRANSPLANT. Russian Journal of Transplantology and Artificial Organs. 2013;15(4):112-125. (In Russ.) https://doi.org/10.15825/1995-1191-2013-4-112-125