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Вестник трансплантологии и искусственных органов

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ОБСЛЕДОВАНИЕ, ОТБОР И ПОДГОТОВКА ПРИЖИЗНЕННЫХ ДОНОРОВ ФРАГМЕНТА ПЕЧЕНИ ДЛЯ ТРАНСПЛАНТАЦИИ ДЕТЯМ

https://doi.org/10.15825/1995-1191-2015-1-134-146

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Аннотация

Трансплантация фрагментов печени от прижизненного донора является высокоэффективным методом помощи детям с терминальными заболеваниями печени. Прогнозируемый успех операции во многом определяется на этапе отбора потенциального донора. В обзоре литературы представлена историческая справка, рассмотрены «западный» и «восточный» опыт развития трансплантации печени, проанализированы этические и психосоциальные аспекты прижизненного донорства фрагментов печени, а также изложены принципы и протоколы отбора потенциальных доноров. Кроме того, представлены современные взгляды на оценку объема печени потенциального донора, выбора фрагмента для трансплантации, в том числе для детей с малой массой тела. 

Об авторах

С. В. Готье
ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава РФ, Москва, Российская Федерация
Россия


А. Р. Монахов
ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава РФ, Москва, Российская Федерация
Россия


Список литературы

1. Готье СВ, Ким ЭФ, Цирульникова ОМ, Хизроев ХМ, Аммосов АА, Ховрин ВВ. Клинические аспекты получения фрагментов печени от живых родственных доноров. Бюллетень сибирской медицины. 2007; 1 (3): 51–60. Gautier SV, Kim EF, Tsirulnikova OM, Khizroyev KM, Ammosov AA, Khovrin VV. Clinical aspects of living related liver grafts harvesting. Byulleten sibirskoy meditsiny. 2007; 1 (3): 51–60.

2. Готье СВ, Баранов АА, Каганов БС, Зайнудинов ЗМ. Трансплантация печени у детей: состояние проблемы. Рос. педиат. журн. 2003; 1: 39–44. Gautier SV, Baranov AA, Kaganov BS, Zaynudinov ZM. Transplantatsiya pecheni u detey: sostoyaniye problemy. Ros. pediat. zhurn. 2003; 1: 39–44.

3. Готье СВ, Константинов БА, Цирульникова ОМ. Трансплантация печени. Москва: МИА (2008); 73– 74. Gautier SV, Konstantinov BA, Tsirulnikova OM. Transplantatsiya pecheni. Moscow: MIA (2008): 73–74.

4. Демихов ВП. Пересадка жизненно важных органов в эксперименте. М.: Медгиз (1960): 260. Demikhov VP. Peresadka zhiznenno vazhnykh organov v eksperimente. M.: Medgiz (1960): 260.

5. Ким ЭФ. Клинические и хирургические аспекты прижизненного донорства фрагментов печени: автореферат дис. ... докт. мед. наук. М., 2008: 41. Kim EF. Klinicheskiye i khirurgicheskiye aspekty prizhiznennogo donorstva fragmentov pecheni: Dissertation. M., 2008: 41.

6. Константинов БА, Готье СВ. Трансплантация печени в России: проблемы, перспективы ближайшего десятилетия. Анн. хир. гепатол. 1998; 3 (2): 119–121. Konstantinov BA, Gautier SV. Transplantatsiya pecheni v Rossii: problemy, perspektivy blizhayshego desyatiletiya. Ann. khir. gepatol. 1998; 3 (2): 119–112.

7. Крыжановская ЕЮ. Комплексное ультразвуковое исследование трансплантата правой доли печени от живого родственного донора: дис. ... канд. мед. наук. М., 2005: 127 с. Kryzhanovskaya EY. Kompleksnoye ultrazvukovoye issledovaniye transplantata pravoy doli pecheni ot zhivogo rodstvennogo donora: Dissertation. М., 2005: 127.

8. Семенков АС. Родственные доноры для трансплантации печени: отбор и хирургическая тактика: автореферат дис. ... канд. мед. наук. М., 2003: 23. Semenkov AS. Rodstvennyye donory dlya transplantatsii pecheni: otbor i khirurgicheskaya taktika: Dissertation. М., 2003: 5–18.

9. Цирульникова ИЕ. Трансплантация печени детям от AB0-несовместимых доноров: автореферат дис. ... канд. мед. наук. М., 2014: 22. Tsirulnikova IE. Transplantatsiya pecheni detyam ot AB0-nesovmestimykh donorov: Dissertation. М., 2014: 22.

10. Шумаков ВИ, Гальперин ЭИ, Неклюдова ЕА. Трансплантация печени. М.: Медицина, 1981: 288. Shumakov VI, Galperin EI, Neklyudova ЕA. Transplantatsiya pecheni. M.: Medicina, 1981: 288.

11. Arnon R, Annunziato R, Miloh T, et al. Liver transplantation in children weighing 5 kg or less: analysis of the UNOS database. Pediatr Transplant. 2011; 15 (6): 650– 658. doi:10.1111/j.1399-3046.2011.01549.x.

12. Azouz SM, Diamond IR, Fecteau A. Graft type in pediatric liver transplantation. Curr Opin Organ Transplant. 2011; 16: 494–498. doi:10.1097/MOT.0b013e32834a8c9c.

13. Baker TB, Jay CL, Ladner DP et al. Laparoscopy-assisted and open liv-ing donor right hepatectomy: a comparative study of outcomes. Surgery. 2009; 146: 817–823.

14. Baker TB, Spicer HG. The History of Living Donor. Advocacy in Living Donor Transplantation. Steel J, editor. Living Donor Advocacy: An Evolving Role Within Transplantation. New York: Springer 2014: 103–118.

15. Barr ML, Belghiti J, Villamil FG et al. A report of the Vancouver Forum on the care of the live organ donor: lung, liver, pancreas, and intestine data and medical guidelines. Transplantation. 2006; 81 (10): 1373–1385. doi:10.1097/01.tp.0000216825.56841.cd.

16. Belzer FO., Southard JH. Principles of solid-organ preservation by cold storage. Transplantation. 1998; 45: 673–676.

17. Bismuth H, Houssin D. Reduced-Sized Orthotopic Liver Graft in Hepatic Transplantation in Children. Surgery. 1984; 95: 367–370. doi:10.1016/S0022-3468(85)80431-0.

18. Bourdeaux C, Darwish A, Jamart J et al. Living-related versus deceased donor pediatric liver transplantation: a multivariate analysis of technical and immunological complications in 235 recipients. Am. J. Transplant. 2007; 7 (2): 440–447. doi:10.1111/j.1600-6143.2006.01626.x.

19. Broelsch CE, Whitington PF, Emond JC, Heffron TG, Thistlethwaite JR, Stevens L et al. Liver transplantation in children from living related donors. Surgical techniques and results. Ann Surg. 1991; 214: 428–437 discussion 437–439.

20. Brown RS. Live donors in liver transplantation. Gastroenterology. 2008; 134 (6): 1802–1813. doi:10.1053/j. gastro.2008.02.092.

21. Calne RY, Rolles K, White DJG. Cyclosporin A initially as the only immunosupressant in 34 recipients of cadaveric organs: 32 kidney, 2 pancreas, and 2 livers. Lancet. 1979; 2: 1033–1036.

22. Calne RC. Liver Transplantation. London: Grune & Stratton. 1987.

23. Caruso S, Miraglia R, Maruzzelli L, Gruttadauria S, Luca A, Gridelli B. Imaging in liver transplantation. World J. Gastroenterol. 2009; 15: 675–683.

24. Catalano OA, Singh AH, Uppot RN, Hahn PF, Ferrone CR, Sahani DV. Vascular and biliary variants in the liver: implications for liver surgery. Radiographics. 2008; 28 (2): 359–378. doi:10.1148/rg.282075099.

25. Cauchy F, Schwarz L, Scatton O, Soubrane O. Laparoscopic liver resection for living donation: where do we stand? World J. Gastroenterol. 2014; 20 (42): 15590– 15598. doi:10.3748/wjg.v20.i42.15590.

26. Cauley RP, Vakili K, Potanos K et al. Deceased donor liver transplantation in infants and small children: Are partial grafts riskier than whole organs? Liver TransF9. plant. 2013; 19: 721–729. doi:10.1002/lt.23667.

27. Cho JY, Suh KS, Kwon CH, Yi NJ, Lee KU. Mild hepatic steatosis is not a major risk factor for hepatectomy and regenerative power is not impaired. Surgery. 2006; 139: 508–515. doi:10.1016/j.surg.2005.09.007.

28. Emond JС, Lobritto SJ, Jan D. Donor Evaluation, Surgical Technique and Perioperative Management. Fine RN, Webber SA, Olthoff KM, Kelly DA, Harmon WE, editors. Pediatric solid organ transplantation. 2nd ed. Malden: Blackwell Publishing; 2007: 213–226.

29. Emre S, Umman V, Cimsit B, Rosencrantz R. Current concepts in pediatric liver transplantation. Mt Sinai J. Med. 2012; 79 (2): 199–213. doi:10.1002/msj.21305.

30. Fan ST. Living Donor Liver Transplantation. 2th ed. London: World Scientific Publishing; 2011: 11–42.

31. Goodrich EO Jr, Welch HF, Nelson JA, Beecher TS, Welch CS. Homotransplantation of the canine liver. Surgery. 1956; 39: 244–251.

32. Heffron T, Welch D, Pillen T et al. Successful AB0-in-compatible pediatric liver transplantation utilizing standard immunosuppression with selective postoperative plasmapheresis. Liver Transpl. 2006; 12 (6): 972–978. doi:10.1002/lt.20760.

33. Herden U, Grabhorn E, Briem-Richter A, Ganschow R, Nashan B, Fischer L. Developments in pediatric liver transplantation since implementation of the new allocation rules in Eurotransplant. Clin. Transplant. 2014; 28 (9): 1061–1068. doi:10.1111/ctr.12420.

34. Herden U, Wischhusen F, Heinemann A et al. A formula to calculate the standard liver volume in children and its application in pediatric liver transplantation. Transpl. Int. 2013; 26: 1217–1224. doi:10.1111/tri.12198.

35. Hsu SL, Chen TY, Huang TL et al. Left-sided gallbladder: Its clinical significance and imaging presentations. World J. Gastroenterol. 2007; 13: 6404–6409. doi:10.3748/ wjg.13.6404.

36. Jamieson NV, Sundberg R, Lindell S. Preservation of the canine liver for 24–48 hours using simple cold storage with UW solution. Transplantation. 1988; 46: 517–525.

37. Jin Y-J, Kim KM, Hwang S et al. Exercise and diet modification in non-obese non-alcoholic fatty liver disease: analysis of biopsies of living liver donors. J. Gastroenterol Hepatol. 2012; 27 (8): 1341–1347. doi:10.1111/ j.1440–1746.2012.07165.x.

38. Jy L, Ln Y. Transfusion rate for 500 consecutive living donor liver transplantations: experience of one liver transplantation center. Transplantation. 2012; 94: 66–67.

39. Kaido T, Uemoto S. Does living donation have advantages over deceased donation in liver transplantation? J. Gastroenterol. Hepatol. 2010; 25 (10): 1598–1603. doi:10.1111/j.1440-1746.2010.06418.x.

40. Kanazawa H, Sakamoto S, Fukuda A et al. Living-donor liver transplantation with hyperreduced left lateral segment grafts: a single-center experience. Transplantation. 2013; 95: 750–754. doi:10.1097/TP.0b013e31827a93b4.

41. Kasahara M, Kaihara S, Oike F et al. Living-donor liver transplantation with monosegments. Transplantation. 2003; 76: 694–696. doi:10.1097/01.TP.0000079446.94204.

42. Kasahara M, Sakamoto S, Shigeta T, et al. Reducing the thickness of left lateral segment grafts in neonatal living donor liver transplantation. Liver Transplant. 2013;19:226–228. doi:10.1002/lt.23572.

43. Kasahara M, Umeshita K, Inomata Y, Uemoto S. Longterm outcomes of pediatric living donor liver transplantation in Japan: An analysis of more than 2200 cases listed in the registry of the japanese liver transplantation society. Am. J. Transplant. 2013; 13 (7): 1830–1839. doi:10.1002/ajt.12276.

44. Kim JM, Kim KM, Yi NJ et al. Pediatric liver transplantation outcomes in Korea. J. Korean Med. Sci. 2013; 28 (1): 42–47.

45. Kim KH, Jung DH, Park KM et al. Comparison of open and laparoscopic live donor left lateral sectionectomy. Br. J. Surg. 2011; 98: 1302–1308. doi:10.1002/bjs.7601.

46. Kim KW, Lee J, Lee H et al. Right lobe estimated bloodfree weight for living donor liver transplantation: accuracy of automated blood-free CT volumetry-preliminary results. Radiology. 2010; 256 (2): 433–440. doi:10.1148/ radiol.10091897.

47. Kiuchi T, Kasahara M, Uryuhara K et al. Impact of graft size mismatching on graft prognosis in liver transplantation from living donors. Transplantation. 1999; 67 (2): 321–327. doi:10.1097/00007890-200407271-00107.

48. Kodama Y, Ng CS, Wu TT et al. Comparison of CT methods for determining the fat content of the liver. AJR Am. J. Roentgenol. 2007; 188: 1307–1312. doi:10.2214/ AJR.06.0992.

49. Koffron AJ, Kung R, Baker T, Fryer J, Clark L, Abecassis M. Laparoscopic-assisted right lobe donor hepatectomy. Am. J. Transplant. 2006; 6: 2522–2525. doi:10.1111/ j.1600-6143.2006.01498.x.

50. Lee SS, Park SH, Kim HJ et al. Non-invasive assessment of hepatic steatosis: Prospective comparison of the accuracy of imaging examinations. J. Hepatol. 2010; 52: 579–585. doi:10.1016/j.jhep.2010.01.008.

51. Lee SW, Park SH, Kim KW et al. Unenhanced CT for assessment of macrovesicular hepatic steatosis in living liver donors: comparison of visual grading with liver attenuation index. Radiology. 2007; 244: 479–485. doi:10.1148/radiol.2442061177.

52. Lee VT, Yip CC, Ganpathi IS, Chang S, Mak KS, Prabhakaran K et al. Expanding the donor pool for liver transplantation in the setting of an «opt-out» scheme: 3 years after new legislation. Ann. Acad. Med. Singapore. 2009; 38: 315–317.

53. Lee W-C, Lee C-S, Soong R-S et al. Split liver transplantation in adults: preoperative estimation of the weight of right and left hemiliver grafts. Liver Transpl. 2011; 17 (1): 93–94. doi:10.1002/lt.22213.

54. Lim MC, Tan CH, Cai J, Zheng J, Kow a. WC. CT volumetry of the liver: Where does it stand in clinical practice? Clin Radiol. 2014; 69 (9): 887–895. doi:10.1016/j.crad.2013.12.021.

55. Lin N-C, Nitta H, Wakabayashi G. Laparoscopic major hepatectomy: a systematic literature review and comparison of 3 techniques. Ann. Surg. 2013; 257 (2): 205– 213. doi:10.1097/SLA.0b013e31827da7fe.

56. Makuuchi M, Kawarazaki H, Iwanaka T, Kamada N, Takayama T, Kumon M. Living related liver transplantation. Surg Today. 1992; 22: 297–300.

57. Malago M, Rogiers X, Burdelski M, Broelsch CE. Living related liver transplantation: 36 cases at the University of Hamburg. Transplant. Proc. 1994; 26: 3620– 3621.

58. McCormack L, Petrowsky H, Jochum W, Furrer K, Clavien P-A. Hepatic steatosis is a risk factor for postoperative complications after major hepatectomy: a matched case-control study. Ann. Surg. 2007; 245: 923–930. doi:10.1097/01.sla.0000251747.80025.b7.

59. Minervini MI, Ruppert K, Fontes P et al. Liver biopsy findings from healthy potential living liver donors: Reasons for disqualification, silent diseases and correlation with liver injury tests. J. Hepatol. 2009; 50: 501–510. doi:10.1016/j.jhep.2008.10.030.

60. Mizuta K, Yasuda Y, Egami S et al. Living donor liver transplantation for neonates using segment 2 monosubsegment graft. Am. J. Transplant. 2010; 10: 2547–2552. doi:10.1111/j.1600-6143.2010.03274.x.

61. Mokry T, Bellemann N, Müller D et al. Accuracy of estimation of graft size for living-related liver transplantation: first results of a semi-automated interactive software for CT-volumetry. PLoS One. 2014; 9 (10): e110201. doi:10.1371/journal.pone.0110201.

62. Nadalin S, Malagó M, Valentin-Gamazo C et al. Preoperative donor liver biopsy for adult living donor liver transplantation: risks and benefits. Liver Transpl. 2005; 11: 980–986. doi:10.1002/lt.20462.

63. Ng KK, Gen F, Lo CM, Edin F. Liver Transplantation in Asia: Past , Present and Future. Ann. Acad. Med. 2009; 38: 322–331.

64. Olthoff KM, Abecassis MM, Emond JC, Kam I, Merion RM, Gillespie BW. Outcomes of adult living donor liver transplantation: comparison of the adult-toadult living donor liver transplantation cohort study and the national experience. Liver Transpl. 2011; 17: 789–797.

65. Otte JB. History of pediatric liver transplantation. Where are we coming from? Where do we stand? Pediatr. Transplant. 2002; 6 (5): 378–387. doi:10.1034/j.1399-3046.2002.01082.x.

66. Papachristou C, Walter M, Klapp BF. Psychological evaluation of living liver donors-A single centre experience. Acta Gastro-Enterologica Belgica. 2010; 73: 383–388.

67. Pichlmayr R, Ringe B, Gubernatis G, Hauss J, Bunzendahl H. Transplantation of a donor liver to 2 recipients (splitting transplantation): a new method in the further development of segmental liver transplantation. Langenbecks Arch. Chir. 1988; 373: 127–130.

68. Quirino L, Jan PL. Regenerative Medicine Applications in Organ Transplantation. London: Elsevier. 2014: 283–298.

69. Raia S, Nery JR, Mies S. Liver transplantation from live donors. Lancet. 1989; 2: 497.

70. Rinella ME, Alonso E, Rao S et al. Body mass index as a predictor of hepatic steatosis in living liver donors. Liver Transpl. 2001; 7 (5): 409–414. doi:10.1053/ jlts.2001.23787.

71. Sakamoto S, Kanazawa H, Shigeta T et al. Technical considerations of living donor hepatectomy of segment 2 grafts for infants. Surgery. 2014; 156 (5): 1232–1237. doi:10.1016/j.surg.2014.05.003.

72. Scatton O, Katsanos G, Boillot O et al. Pure Laparoscopic Left Lateral Sectionectomy in Living Donors: From Innovation to Development in France. Ann. Surg. 2014. doi:10.1097/SLA.0000000000000642.

73. Sharma A, Ashworth A, Behnke M, Cotterell A, Posner M, Fisher RA. Donor selection for adult-to-adult living donor liver transplantation: well begun is half done. Transplantation. 2013; 95 (3): 501–506. doi:10.1097/ TP.0b013e318274aba1.

74. Shin YH, Ko JS, Kim GS et al. Impact of hepatic macrovesicular and microvesicular steatosis on the postoperative liver functions after right hepatectomy in living donors. Transplant. Proc. 2012; 44: 512–515. doi:10.1016/j. transproceed.2012.02.005.

75. Shirouzu Y, Kasahara M, Morioka D et al. Vascular reconstruction and complications in living donor liver transplantation in infants weighing less then 6 kilograms: The Kyoto experience. Liver Transplant. 2006; 12: 1224–1232. doi:10.1002/lt.20800.

76. Simpson MA, Pomfret EA. Checking the harness: safety for living liver donors. Liver Transpl. 2012; 18 (2): 15–19. doi:10.1002/lt.23525.

77. Singer PA, Siegler M, Whitington PF. Ethics of liver transplantation with living donors. N. Engl. J. Med. 1989; 321: 620–622.

78. Soin AS, Kakodkar R. Living donor liver transplantation in India. Trop. Gastroenterol. 2007; 28: 96–98.

79. Song G-W, Lee S-G. Living donor liver transplantation. Curr. Opin Organ Transplant. 2014; 19 (3): 217–222. doi:10.1097/MOT.0000000000000088.

80. Soubrane O, Perdigao Cotta F, Scatton O. Pure laparoscopic right hepatectomy in a living donor. Am. J. Transplant. 2013; 13 (1): 2467–2471. doi:10.1111/ajt.12361.

81. Starzl TE, Groth CG, Brettschneider L. Orthotopic homotransplantation of the human liver. Ann. Surg. 1968; 168: 392–415.

82. Starzl TE, Marchioro TL, Porter KA. The role of organ transplantation in pediatrics. Pediatr. Clin. N. Am. 1966; 13: 381.

83. Starzl TE. The puzzle people: Memoirs of a transplant surgeon. Pittsburgh, PA: University of Pittsburgh Press. 1992; 364.

84. Starzl TE. Experience in Hepatic Transplantation WB Saunders Company, Philadelphia, PA. 1969.

85. Statistics.Eurotransplant.org [Internet]. Leiden: Eurotransplant International Foundation; available from: http://www. statistics.eurotransplant.org

86. Steering Committee of the Istanbul Summit. Organ trafficking and transplant tourism and commercialism: the Declaration of Istanbul. Lancet. 2008; 372: 5–6. doi:10.1016/S0140-6736(08)60967-8.

87. Strong RW, Lynch SV, Ong TH. Successful liver transplantation from a living donor to her son. N. Engl. J. Med. 1990; 322: 1505–1507.

88. Tanaka K, Inomata Y. Living Related Liver Transplantation in Pediatric Recipients. Busuttil RW, Klintmalm GB, editors. Transplantation of the Liver. Philadelphia: Elsevier; 2005; 629–645.

89. Tanaka K, Ogura Y, Kiuchi T, Inomata Y, Uemoto S, Furukawa H. Living donor liver transplantation: Eastern experiences. HPB (Oxford). 2004; 6 (2): 88–94. doi:10.1080/13651820310020765.

90. Thys K, Schwering K-L, Siebelink M et al. Psychosocial impact of pediatric living-donor kidney and liver transplantation on recipients, donors, and the family: a systematic review. Transpl. Int. 2014. doi:10.1111/ tri.12481.

91. Tongyoo А., Pomfret EА, Pomposelli JJ. Accurate estimation of living donor right hemi-liver volume from portal vein diameter measurement and standard liver volume calculation. Am. J. Transplant. 2012; 12 (2): 1229–1239. doi:10.1111/j.1600-6143.2011.03909.x.

92. Tran TT, Changsri C, Shackleton CR, et al. Living donor liver transplantation: Histological abnormalities found on liver biopsies of apparently healthy potential donors. J. Gastroenterol. Hepatol. 2006; 21: 381–383. doi:10.1111/j.1440-1746.2005.03968.x.

93. Transpl.ru/specialist/rto [Internet]. Moscow: Russian transplantation society. available from: http://transpl.ru/ files/npa/nacional_nye_klinicheskie_rekomendacii_po_ prizhiznennomu_ donorstvu_fragmenta_ pecheni.pdf

94. Uchiyama H, Kayashima H, Matono R et al. Relevance of HLA compatibility in living donor liver transplantation: the double-edged sword associated with the patient outcome. Clin. Transplant. 2012; 26 (5): E522–E529. doi:10.1111/ctr.12019.

95. Valentín-Gamazo C, Malagó M, Karliova M, et al. Experience after the evaluation of 700 potential donors for living donor liver transplantation in a single center. Liver Transpl. 2004; 10 (9): 1087–1096. doi:10.1002/lt.20223.

96. Vohra S, Goyal N, Gupta S. Preoperative CT evaluation of potential donors in living donor liver transplantation. Indian J. Radiol. Imaging. 2014; 24 (4): 350–359. doi:10.4103/0971-3026.143897.

97. Walter J, Burdelski M, Bröring DC. Chances and risks in living donor liver transplantation. Dtsch. Arztebl. Int. 2008; 105 (6): 101–107. doi:10.3238/arztebl.2008.0101.

98. Wang F, Pan KT, Chu SY et al. Preoperative estimation of the liver graft weight in adult right lobe living donor liver transplantation using maximal portal vein diameters. Liver Transplant. 2011; 17: 373–380. doi:10.1002/ lt.22274.

99. Williams R, Alisa A, Karani J, Rela M, Heaton N. Living related adult-to-adult liver transplantation: Meeting the donor shortage. Antiviral Res. 2001; 52: 217–223. doi:10.1016/S0166-3542(01)00187-5.

100. www.Organdonor.gov [Internet]. U.S. Government Information on Organ and Tissue Donation and Transplantation: ACOT website HHS Archive. Accessed 15 May 2013; available from: http://www. organdonor.gov

101. Yigitler C, Farges O, Kianmanesh R, Regimbeau JM, Abdalla EK, Belghiti J. The small remnant liver after major liver resection: How common and how relevant? Liver Transplant. 2003; 9 (9): 18–25. doi:10.1053/ jlts.2003.50194.

102. Yoon JH, Lee JM, Jun JH et al. Feasibility of three-dimensional virtual surgical planning in living liver donors. Abdom. Imaging. 2014. doi:10.1007/s00261-0140231-9.

103. Zhou J, Shen Z, He Y, Zheng S, Fan J. The current status of pediatric liver transplantation in Mainland China. Pediatr. Transplant. 2010; 14 (May 2007): 575–582. doi:10.1111/j.1399-3046.2010.01340.x.

104. Zhuang ZG, Qian LJ, Gong HX et al. Multidetector computed tomography angiography in the evaluation of potential living donors for liver transplantation: singlecenter experience in China. Transpl. Proc. 2008; 40: 2466–2477. doi:10.1016/j.transproceed.2008.08.031.


Для цитирования:


Готье С.В., Монахов А.Р. ОБСЛЕДОВАНИЕ, ОТБОР И ПОДГОТОВКА ПРИЖИЗНЕННЫХ ДОНОРОВ ФРАГМЕНТА ПЕЧЕНИ ДЛЯ ТРАНСПЛАНТАЦИИ ДЕТЯМ. Вестник трансплантологии и искусственных органов. 2015;17(1):134-146. https://doi.org/10.15825/1995-1191-2015-1-134-146

For citation:


Gautier S.V., Monakhov A.R. EVALUATION, SELECTION AND PREPARATION OF LIVING DONOR FOR PARTIAL LIVER TRANSPLANTATION IN CHILDREN. Russian Journal of Transplantology and Artificial Organs. 2015;17(1):134-146. (In Russ.) https://doi.org/10.15825/1995-1191-2015-1-134-146

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ISSN 1995-1191 (Print)
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