BLOOD CONCENTRATIONS OF NITRITE/NITRATE (NOx), METHEMOGLOBIN, LACTATE AND THEIR CORRELATION IN PATIENS AFTER LUNG TRANSPLANTATION DURING TREATMENT WITH INHALED NITRIC OXIDE
https://doi.org/10.15825/1995-1191-2013-3-38-43
Abstract
Aim. The purpose of the research was correlation analysis of iNO, blood levels of NOx, MetHb and lacta- te in patients after LT. Materials and methods. The duration of iNO therapy was ranged from 2 to 4 days, the data of LT were analyzed in 7 patients. Results. There was a significant increase of NOx and lac- tate levels from 1 to 5 days after operation while the concentration of MetHb remained within the normal range. We have found significant positive correlations in patients after LT: between iNO and NOx concen- tration, iNO and MetHb concentration, iNO and lactate concentration, the concentration of NOx and Me- tHb, the concentration of NOx and lactate, the concentration of MetHb and lactate. Conclusion. The ob- tained data indicate that during application of iNO in patients with LT it is necessary to control both the concentration of administered iNO, the concentration of MetHb in blood and the level of NOx in serum.
About the Authors
M. Sh. Khubutiya
Sklifosovsky Research Institute for Emergency Medicine Health Department of Moscow (director – corresponding-member of RAMSci, prof. Khubutiya M.S.), Moscow,
Russian Federation
Russian Federation
Russian Federation
M. M. Abakumov
Sklifosovsky Research Institute for Emergency Medicine Health Department of Moscow (director – corresponding-member of RAMSci, prof. Khubutiya M.S.), Moscow,
Russian Federation
Russian Federation
Russian Federation
E. V. Klychnikova
Sklifosovsky Research Institute for Emergency Medicine Health Department of Moscow (director – corresponding-member of RAMSci, prof. Khubutiya M.S.), Moscow,
Russian Federation
Russian Federation
Russian Federation
E. A. Tarabrin
Sklifosovsky Research Institute for Emergency Medicine Health Department of Moscow (director – corresponding-member of RAMSci, prof. Khubutiya M.S.), Moscow,
Russian Federation
Russian Federation
Russian Federation
E. V. Tazina
Sklifosovsky Research Institute for Emergency Medicine Health Department of Moscow (director – corresponding-member of RAMSci, prof. Khubutiya M.S.), Moscow,
Russian Federation
Russian Federation
Russian Federation
M. A. Godkov
Sklifosovsky Research Institute for Emergency Medicine Health Department of Moscow (director – corresponding-member of RAMSci, prof. Khubutiya M.S.), Moscow,
Russian Federation
Russian Federation
Russian Federation
A. A. Romanov
Sklifosovsky Research Institute for Emergency Medicine Health Department of Moscow (director – corresponding-member of RAMSci, prof. Khubutiya M.S.), Moscow,
Russian Federation
Russian Federation
Russian Federation
O. A. Kurilova
Sklifosovsky Research Institute for Emergency Medicine Health Department of Moscow (director – corresponding-member of RAMSci, prof. Khubutiya M.S.), Moscow,
Russian Federation
Russian Federation
Russian Federation
E. I. Pervakova
Sklifosovsky Research Institute for Emergency Medicine Health Department of Moscow (director – corresponding-member of RAMSci, prof. Khubutiya M.S.), Moscow,
Russian Federation
Russian Federation
Russian Federation
D. Kh. Tsurova
Sklifosovsky Research Institute for Emergency Medicine Health Department of Moscow (director – corresponding-member of RAMSci, prof. Khubutiya M.S.), Moscow,
Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Khubutiya M.Sh., Abakumov M.M., Klychnikova E.V., Tarabrin E.A., Tazina E.V., Godkov M.A., Romanov A.A., Kurilova O.A., Pervakova E.I., Tsurova D.Kh. BLOOD CONCENTRATIONS OF NITRITE/NITRATE (NOx), METHEMOGLOBIN, LACTATE AND THEIR CORRELATION IN PATIENS AFTER LUNG TRANSPLANTATION DURING TREATMENT WITH INHALED NITRIC OXIDE. Russian Journal of Transplantology and Artificial Organs. 2013;15(3):38-43. (In Russ.) https://doi.org/10.15825/1995-1191-2013-3-38-43
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