ALLOTRANSPLANTATION OF MACROENCAPSULATED PARATHYROID CELLS IN SEVERE POSTSURGICAL HYPOPARATHYROIDISM: A CASE REPORT
https://doi.org/10.15825/1995-1191-2011-4-60-65
Abstract
The last therapeutic alternative in severe postsurgical hypoparathyroidism is allotransplantation of macroen- capsulated parathyroid cells. With this technique, it is possible to implant cells or tissue of parathyroid origin to replace them in such patients, without immusupression. We report an allotransplant of parathyroid cells in a patient with continous endovenous requirement of calcium to survive. The macroencapsulation was carried out with a polyvinylidine difluoride (PVDF). We implant ~100 000 parathyroid cells in the deep femoral artery. In this article, we show functionality of the graft for at least 3 months without requirement of endovenous calcium. We report this procedure as a therapeutical alternative in severe hypoparathyroidism.
About the Authors
V. Ja. Khryshchanovich
Belarusian State Medical University
Russian Federation
Russian Federation
S. I. Tretyak
Belarusian State Medical University
Russian Federation
Russian Federation
A. N. Kharlamova
Belarusian State Medical University
Russian Federation
Russian Federation
T. V. Mochort
Belarusian State Medical University
Russian Federation
Russian Federation
E. V. Bogomazova
Belarusian State Medical University
Russian Federation
Russian Federation
E. I. Kuzmenkova
Republic rehabilitation and balneotherapy centre
Russian Federation
Russian Federation
V. A. Kondratovich
Minsk clinical oncological hospital
Russian Federation
Russian Federation
A. M. Pisarenko
Minsk clinical oncological hospital
Russian Federation
Russian Federation
A. V. Romanovich
4th Minsk clinical hospital
Russian Federation
Russian Federation
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Review
For citations:
Khryshchanovich V.J., Tretyak S.I., Kharlamova A.N., Mochort T.V., Bogomazova E.V., Kuzmenkova E.I., Kondratovich V.A., Pisarenko A.M., Romanovich A.V. ALLOTRANSPLANTATION OF MACROENCAPSULATED PARATHYROID CELLS IN SEVERE POSTSURGICAL HYPOPARATHYROIDISM: A CASE REPORT. Russian Journal of Transplantology and Artificial Organs. 2011;13(4):60-65. (In Russ.) https://doi.org/10.15825/1995-1191-2011-4-60-65
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