SINGLE-CENTER EXPERIENCE OF ABO-INCOMPATIBLE LIVER TRANSPLANTATION
https://doi.org/10.15825/1995-1191-2011-2-21-28
Abstract
Since 2008 up to 2010 eight ABO-incompatible liver transplantations have been performed in our center: one of them was urgent liver transplantation to adult patient from deceased donor, other seven were transplantations of left lateral segment to children from living relative donors. Own experience, as well as world one, proves, that barrier of ABO-incompatibility can be overcome more successfully in liver transplantation, particularly in pediatric population, that in other solid organs transplantation. Good results can be achieved even with less ag- gressive immunosuppressive therapy. Recipient conditioning before operation can significantly improve results of ABO-incompatible liver transplantation, but as own experience has shown, often there’s no need to hold some special preparation of children, because their anti-ABO antibodies are very low or absent before transplantation and do not increase after it. Thereby ABO-incompatible liver transplantation is reasonable in urgent cases and in pediatric population because of the limited pull of living relative donors for children.
About the Authors
S. V. GautierRussian Federation
O. M. Tsirulnikova
Russian Federation
A. A. Ammosov
Russian Federation
Y. E. Lurie
Russian Federation
Y. G. Moysyuk
Russian Federation
V. N. Poptsov
Russian Federation
I. V. Pogrebnichenko
Russian Federation
A. C. Porunova
Russian Federation
N. P. Obraztsova
Russian Federation
I. E. Tsirulnikova
Russian Federation
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Review
For citations:
Gautier S.V., Tsirulnikova O.M., Ammosov A.A., Lurie Y.E., Moysyuk Y.G., Poptsov V.N., Pogrebnichenko I.V., Porunova A.C., Obraztsova N.P., Tsirulnikova I.E. SINGLE-CENTER EXPERIENCE OF ABO-INCOMPATIBLE LIVER TRANSPLANTATION. Russian Journal of Transplantology and Artificial Organs. 2011;13(2):21-28. (In Russ.) https://doi.org/10.15825/1995-1191-2011-2-21-28