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THE PANCREAS OF NEWBORN RABBITS AS A SOURCE OF PROGENITOR CELLS

https://doi.org/10.15825/1995-1191-2011-1-61-64

Abstract

The newborn rabbit pancreas was used as a source of ductal epithelial cells. Our approach includes the cultiva- tion of pancreatic tissue microfragments without preliminary islet and duct isolation. Under ordinary conditions we found the epithelial pancreatic cell monolayer. The cultivated monolayer cells were shown by immunofluo- rescence to express special ductal cytokeratin 19 and were insulin- and glucagon-negative for 7–15 days. 

About the Authors

L. A. Kirsanova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


N. V. Baranova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


N. N. Skaletsky
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


V. A. Zaidenov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


G. N. Bubentsova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


I. A. Pushkova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation


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Review

For citations:


Kirsanova L.A., Baranova N.V., Skaletsky N.N., Zaidenov V.A., Bubentsova G.N., Pushkova I.A. THE PANCREAS OF NEWBORN RABBITS AS A SOURCE OF PROGENITOR CELLS. Russian Journal of Transplantology and Artificial Organs. 2011;13(1):61-64. (In Russ.) https://doi.org/10.15825/1995-1191-2011-1-61-64

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ISSN 1995-1191 (Print)