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BIOCHEMICAL BONE MARKERS AS PREDICTORS OF BONE LOSSES FOLLOWING LIVER TRANSPLANTATION

https://doi.org/10.15825/1995-1191-2010-3-52-61

Abstract

24 recipients after ortotopic liver transplantation (9 women and 5 men) 18–57 years aged were studied in 1–2 and then through 4–18 months following operation. Bone mineral density (BMD) in repeated estimation in 13 recipients was elevated on 14 ± 10,5% and in 11 recipients was decreased on 2,5 ± 2,56%. BMD elevation was associated with bone remodelling normalization. BMD lowering followed transplant dysfunction, glucocorticoid therapy, bone resorption increasing and bone formation suppression. 

About the Authors

V. P. Buzulina
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moskow
Russian Federation


I. A. Pronchenko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moskow
Russian Federation


I. P. Yermakova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moskow
Russian Federation


E. B. Yaroshenko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moskow
Russian Federation


M. N. Kornilov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moskow
Russian Federation


N. P. Shmerko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moskow
Russian Federation


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Review

For citations:


Buzulina V.P., Pronchenko I.A., Yermakova I.P., Yaroshenko E.B., Kornilov M.N., Shmerko N.P. BIOCHEMICAL BONE MARKERS AS PREDICTORS OF BONE LOSSES FOLLOWING LIVER TRANSPLANTATION. Russian Journal of Transplantology and Artificial Organs. 2010;12(3):52-61. (In Russ.) https://doi.org/10.15825/1995-1191-2010-3-52-61

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ISSN 1995-1191 (Print)