EXPERIMENTAL SUBSTANTIATION OF APPLICATION GEL IMPLANT «SFERO®GEL» AND FILM IMPLANT «ELASTOPOB»® AT A TRAUMA OF PERIPHERAL NERVOUS SYSTEM IN EXPERIMENT
https://doi.org/10.15825/1995-1191-2009-4-75-80
Abstract
The purpose of the present work was the experimental substantiation of application of new biodegraded materials: gel implant «Sfero®Gel» and a film membrane of «ElastoPOB»® a domestic production, in surgery of defeats of peripheral nerves. Experimental researches carried out on females of nonlinear rats, is powerful 200–250 gramme. In experience 10 animals are used, 20 operative interventions on sciatic nerves are executed. Morphological studying of the received material in 101 days after operation was carried out. At application of a membrane «ElastoPOB»® it was defined delimitin of peripheral nerves from surrounding tissue. A film membrane of «ElastoPOB»® is perspective to apply at traumas of a nervous fabric for the purpose of formation of a friable hem in a damage zone. On the basis of the received experimental data it is possible to make the conclusion about possibility and expediency of application of biodegraded materials in surgical treatment of defeats of peripheral nervous system.
About the Authors
A. G. Fedyakov
Russian Medical Academy of Postgraduate education, neurosurgery deparment, Moscow
Russian Federation
Russian Federation
O. N. Dreval
Russian Medical Academy of Postgraduate education, neurosurgery deparment, Moscow
Russian Federation
Russian Federation
A. V. Kouznetsov
Russian Medical Academy of Postgraduate education, neurosurgery deparment, Moscow
Russian Federation
Russian Federation
V. I. Sevastianov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Center for biomaterials research, Moscow
Russian Federation
Russian Federation
N. V. Perova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Center for biomaterials research, Moscow
Russian Federation
Russian Federation
E. A. Nemets
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Center for biomaterials research, Moscow
Russian Federation
Russian Federation
F. S. Satanova
Research Institute of Nevrology Russian Academy of Medical Scienses, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Fedyakov A.G., Dreval O.N., Kouznetsov A.V., Sevastianov V.I., Perova N.V., Nemets E.A., Satanova F.S. EXPERIMENTAL SUBSTANTIATION OF APPLICATION GEL IMPLANT «SFERO®GEL» AND FILM IMPLANT «ELASTOPOB»® AT A TRAUMA OF PERIPHERAL NERVOUS SYSTEM IN EXPERIMENT. Russian Journal of Transplantology and Artificial Organs. 2009;11(4):75-80. (In Russ.) https://doi.org/10.15825/1995-1191-2009-4-75-80
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