VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION
https://doi.org/10.15825/1995-1191-2009-4-18-25
Abstract
The article focuses on the results of the investigation of peripheral blood lymphocyte morphofunctional status in healthy volunteers and renal allograft recipients for early postoperative period. Working out noninvasive tests for diagnosis of acute renal allograft rejection based on the measuring of cell morphometric parameters by method of coherent phase microscopy (CPM). It was found out that the lymphocyte phase height was proportional cell image density and its geometrical thickness. Our results showed that the variations of immunocompetent cell morphometric indicants can be in advance the dynamics of blood creatine increasing and answer for early criteria of acute renal allograft rejection.
About the Authors
A. V. Vatazin
M.F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow
Russian Federation
Russian Federation
I. A. Vasilenko
Russian Research Clinical Centre of Gerontology, Moscow
Russian Federation
Russian Federation
A. L. Valov
Russian Children Clinical Hospital, Moscow
Russian Federation
Russian Federation
V. B. Metelin
Russian Research Clinical Centre of Gerontology, Moscow
Russian Federation
Russian Federation
E. E. Kruglov
M.F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow
Russian Federation
Russian Federation
A. Ya. Tsalman
M.F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Vatazin A.V., Vasilenko I.A., Valov A.L., Metelin V.B., Kruglov E.E., Tsalman A.Ya. VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION. Russian Journal of Transplantology and Artificial Organs. 2009;11(4):18-25. (In Russ.) https://doi.org/10.15825/1995-1191-2009-4-18-25
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