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Russian Journal of Transplantology and Artificial Organs

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PROLONGED MASSIVE POLYURIA AFTER RENAL TRANSPLANTATION

https://doi.org/10.15825/1995-1191-2012-4-89-92

Abstract

Clinical case of prolonged massive polyuria in patient after renal transplantation is represented in this article. Polyuria lasted for a forty days after kidney transplantation, the larges amount of urine output was 55 litres per day. Analysis of transplant biopsy revealed acute tubular necrosis, initial arteriolosclerosis and suspected acute rejection. Doppler ultrasound study and perfusion scintigraphy detected no pathology. At first we tried to decrease the volume of infusion and fluid intake. Also we performed pulse therapy with methylprednisolone. However, these efforts were not effective. Using of a large doses of «Minerin» (posterior pituitary antidiuretic factor) allowed to decrease and stabilize the volume of urine output. The patient was discharge from clinic on day 42 after transplantation. 

About the Authors

A. M. Chernyavskiy
Academician E.N. Meshalkin Novosibirsk State Research Institute of Circulation Pathology, Ministry for Public Health Care & Social Development RF
Russian Federation


I. V. Karpenko
Academician E.N. Meshalkin Novosibirsk State Research Institute of Circulation Pathology, Ministry for Public Health Care & Social Development RF
Russian Federation


A. V. Fomichev
Academician E.N. Meshalkin Novosibirsk State Research Institute of Circulation Pathology, Ministry for Public Health Care & Social Development RF
Russian Federation


A. G. Edemskiy
Academician E.N. Meshalkin Novosibirsk State Research Institute of Circulation Pathology, Ministry for Public Health Care & Social Development RF
Russian Federation


M. N. Deryagin
Academician E.N. Meshalkin Novosibirsk State Research Institute of Circulation Pathology, Ministry for Public Health Care & Social Development RF
Russian Federation


References

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4. Chan M.K., Varghese Z., Fernando O.N., Moorhead J.F. Nocturnal polyuria and saluresis in renal allograft reci- pients // Br. Med. J. 1980 January 19. Vol. 280 (6208). P. 150–151.

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6. James R., Oster M.D., Irwin Singer, MD; LalitaThatte, MD; The Polyuria of Solute Diuresis Arch Intern Med. 1997. Vol. 157 (7). P. 721–729.


Review

For citations:


Chernyavskiy A.M., Karpenko I.V., Fomichev A.V., Edemskiy A.G., Deryagin M.N. PROLONGED MASSIVE POLYURIA AFTER RENAL TRANSPLANTATION. Russian Journal of Transplantology and Artificial Organs. 2012;14(4):89-92. (In Russ.) https://doi.org/10.15825/1995-1191-2012-4-89-92

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ISSN 1995-1191 (Print)