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HOMOCYSTEINЕ AFTER LIVER TRANSPLANTATION IN CHILDREN

https://doi.org/10.15825/1995-1191-2012-4-44-47

Abstract

The research plasma levels of homocysteine (Hcy) in 99 children with congenital and hereditary diseases of hepatobiliary system was performed before liver transplantation. 27% of patients had hyperhomocysteinemia. There was correlation between Hcy levels and sCD40L. High (5.1 μmol/L) pretransplant concentration of Hcy is one of the negative factors that affect function of the liver graft in the early post-transplant period. 

About the Authors

O. P. Shevchenko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, I.M. Sechenov First Moscow State Medical University, Department of transplantology and artificial organs
Russian Federation


V. V. Dolgov
Russian Medical Academy of Postgraduate Education, Moscow


O. E. Gichkun
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, I.M. Sechenov First Moscow State Medical University, Department of transplantology and artificial organs Russian Medical Academy of Postgraduate Education, Moscow


N. V. Kuncevich
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, I.M. Sechenov First Moscow State Medical University, Department of transplantology and artificial organs


O. M Tsirulnikova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, I.M. Sechenov First Moscow State Medical University, Department of transplantology and artificial organs


S. V. Gautier
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, I.M. Sechenov First Moscow State Medical University, Department of transplantology and artificial organs


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Review

For citations:


Shevchenko O.P., Dolgov V.V., Gichkun O.E., Kuncevich N.V., Tsirulnikova O.M., Gautier S.V. HOMOCYSTEINЕ AFTER LIVER TRANSPLANTATION IN CHILDREN. Russian Journal of Transplantology and Artificial Organs. 2012;14(4):44-47. (In Russ.) https://doi.org/10.15825/1995-1191-2012-4-44-47

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ISSN 1995-1191 (Print)