MODIFICATION OF MYOCARDIUM FUNCTION AND PERFUSION AFTER LIVER TRANSPLANTATION. RESULTS OF MYOCARDIAL SCINTIGRAPHY
https://doi.org/10.15825/1995-1191-2014-2-52-59
Abstract
Aim evaluated function and perfusion of myocardium in 12 cirrhotic patients before and after liver transplantation (LT).
Materials and methods. ECG-gated single photon emission computed tomography (SPECT) was used.
Results. It was found that hyperdynamics diminished liver transplantation: left ventricle (LV) end-systolic volume (ESV) rose from 23 to 33 ml (p = 0,026), LV ejection fraction decreased staying normal from 76 до 60% (p = 0,08), calculated cardiac output declined from 4941 to 3066 ml/min (p = 0,009), peak ejection rate (PER) from 314 to 218 ml/sec, (p = 0,003), peak fi lling rate decreased from 248 to 182 ml/sec (p = 0,037), eccentricity coeffi cient also decreased from 0,81 to 0,77 (p = 0,028). Local alteration of perfusion was found only in 2 cases.
Conclusion. Hyperdynamic systolic dysfunction and diastolic dysfunction improve after liver transplantation. Further studies are required to estimate the applicability of SPECT in liver transplantation candidates’ evaluation.
About the Authors
Y.O. Malinovskaya
V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow, Russian
Federation
Russian Federation
Russian Federation
E.N. Ostroumov
V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow, Russian
Federation
Russian Federation
Russian Federation
E.D. Kotina
St. Petersburg State University, St. Petersburg, Russian Federation
Russian Federation
Russian Federation
Y.G. Moysyuk
V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow, Russian Federation
Department of Transplantology and Artificial Organs I.M. Sechenov First Moscow State Medical University, Moscow, Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Malinovskaya Y., Ostroumov E., Kotina E., Moysyuk Y. MODIFICATION OF MYOCARDIUM FUNCTION AND PERFUSION AFTER LIVER TRANSPLANTATION. RESULTS OF MYOCARDIAL SCINTIGRAPHY. Russian Journal of Transplantology and Artificial Organs. 2014;16(2):52-59. (In Russ.) https://doi.org/10.15825/1995-1191-2014-2-52-59
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