Status and trends in chronic kidney disease and renal replacement therapy in the Russian Federation: 2024 Report. Annual monitoring by the Center for Excellence in Medical Care in Nephrology at Shumakov National Medical Research Center of Transplantology and Artificial Organs, Moscow, Russian Federation
https://doi.org/10.15825/1995-1191-2025-3-173-203
Abstract
Objective: to establish and conduct annual monitoring of the status and development trends in nephrology care across the federal subjects of the Russian Federation for the year 2024. Materials and methods. A comprehensive set of indicators was developed, and a structured survey was administered among leading freelance nephrology specialists across the regions. The collected data were systematically analyzed. Results. In 2024, the Russian Federation operated 706 hemodialysis (HD) centers and 49 kidney transplant (KT) centers. A total of 73,483 patients were receiving renal replacement therapy (RRT), of whom 76.6% were on HD, 2.7% on peritoneal dialysis (PD), and 20.6% were being monitored with a functioning kidney transplant. During the year, 1,943 KTs were performed across 49 centers in 38 regions. The overall RRT availability in the Russian Federation was 503.2 patients per million population (pmp), with HD at 385.7 pmp, PD at 13.7 pmp, and KT at 103.8 pmp. Among patients receiving HD in 2024, 81.9% were treated via arteriovenous fistula, 12.1% through permanent central venous catheter, 3.6% via temporary catheter, and 2.4% using vascular prostheses. In 2024, the Russian Federation had 537 nephrology outpatient offices, staffed by 690 physicians providing specialized care. The ratio of outpatient nephrologists to the population was 0.24 per 50,000, significantly below the recommended standard for medical personnel. Inpatient care for patients with pre-dialysis stages of chronic kidney disease (CKD) was delivered through 263 departments, comprising a total of 5,039 beds (equivalent to 0.35 beds per 10,000 population). Morphological evaluation of kidney biopsies – an important indicator of inpatient nephrological care – was independently conducted in 38 regions. Kidney biopsies were performed in 2.5% of patients hospitalized in inpatient facilities, translating to an average of 32.8 biopsies per million population. Conclusion. An annual monitoring framework has been successfully developed, with active collaboration established across regional centers, enabling the collection of up-to-date data on nephrological care in the Russian Federation for 2024. There is no current shortage of dialysis facilities, and a significant proportion of patients receive RRT via HD, an approach that places considerable financial burden on the national healthcare system. The high proportion of working-age individuals (62.4%) among HD patients underscores the substantial socio-economic impact of CKD and its treatment on both the state and society. Although the number of KTs continues to rise annually, current transplant volumes remain insufficient to fully meet demand and only partially offset the growing costs associated with RRT. Expanding the use of PD, particularly in sparsely populated regions, may offer advantages over HD. Nonetheless, KT remains the optimal treatment modality for patients with end-stage CKD, supporting the need to further expand transplant infrastructure and increase access to this intervention. The continuation of annual monitoring across all stages of CKD will allow for data-driven improvements in care delivery, incorporating emerging recommendations and regional insights.
About the Authors
S. V. GautierRussian Federation
Moscow
S. M. Khomyakov
Russian Federation
Sergey M. Khomyakov.
1, Schukinskaya str., Moscow, 123182
Phone: (903) 150-89-55
O. M. Tsirulnikova
Russian Federation
Moscow
N. V. Chebotareva
Russian Federation
Moscow
D. N. Kruglov
Russian Federation
Moscow
References
1. Hill NR, Fatoba ST, Oke JL, Hirst JA, O’Callaghan CA, Lasserson DS et al. Global prevalence of chronic kidney disease – a systematic review and meta-analysis. PloS One. 2016; 11: e0158765. doi: 10.1371/journal.pone.0158765.
2. Sundström J, Bodegard J, Bollmann A, Vervloet MG, Mark PB, Karasik A et al. Prevalence, outcomes, and cost of chronic kidney disease in a contemporary population of 2·4 million patients from 11 countries: The CaReMe CKD study. Lancet Reg Health Eur. 2022 Jun 30; 20: 100438. doi: 10.1016/j.lanepe.2022.100438.
3. Santos-Araújo C, Mendonça L, Carvalho DS, Bernardo F, Pardal M, Couceiro J et al. Twenty years of real-world data to estimate chronic kidney disease prevalence and staging in an unselected population. Clin Kidney J. 2022. 12; 16 (1): 111–124. doi: 10.1093/ckj/sfac206.
4. Heaf J. The Danish Renal Biopsy Register. Kidney Int. 2004; 66 (3): 895–897. doi: 10.1111/j.1523-1755.2004.00832.x.
5. Cunningham A, Benediktsson H, Muruve DA, Hildebrand AM, Ravani P. Trends in Biopsy-Based Diagnosis of Kidney Disease: A Population Study. Can J Kidney Health Dis. 2018; 5: 2054358118799690. doi: 10.1177/2054358118799690.
6. Fiorentino M, Bolignano D, Tesar V, Pisano A, Van Biesen W, D’Arrigo G et al. Renal Biopsy in 2015 – From Epidemiology to Evidence-Based Indications. Am J Nephrol. 2016; 43 (1): 1–19. doi: 10.1159/000444026.
7. Amodu A, Porteny T, Schmidt IM, Ladin K, Waikar SS. Nephrologists’ Attitudes Toward Native Kidney Biopsy: A Qualitative Study. Kidney Med. 2021; 3 (6): 1022–1031. doi: 10.1016/j.xkme.2021.06.014.
8. Molnár A, Thomas MJ, Fintha A, Kardos M, Dobi D, Tislér A et al. Kidney biopsy-based epidemiologic analysis shows growing biopsy rate among the elderly. Sci Rep. 2021; 11 (1): 24479. doi: 10.1038/s41598-021-04274-9.
9. ERA Registry Annual Report 2022; https://www.era-online.org/wp-content/uploads/2024/09/ERA-Registry-Annual-Report2022.pdf.
10. Kotenko ON, Omelyanovsky VV, Ignatyeva VI, Yagnenkova EE, Rumyantseva EI. The cost of chronic kidney disease in the Russian Federation. Clinical nephrology. 2021; 4: 30–38. doi: 10.18565/nephrology.2021.4.30-38.
11. Bello AK, Okpechi IG, Osman MA, Cho Y, Htay H, Jha V et al. Epidemiology of haemodialysis outcomes. Nat Rev Nephrol. 2022; 18 (6): 378–395. doi: 10.1038/s41581-022-00542-7.
12. Andrusev AM, Tomilina NA, Peregudova NG, Shinkarev MB. Kidney replacement therapy for end Stage Kidney Disease in Russian Federation, 2015–2019. Russian National Kidney Replacement Therapy Registry Report of Russian Public Organization of Nephrologists «Russian Dialysis Society». Nephrology and Dialysis. 2021; 23 (3): 255–329. doi: 10.28996/2618-9801-2021-3-255-329.
13. Ficociello LH, Busink E, Sawin DA, Winter A. Global real-world data on hemodiafiltration: An opportunity to complement clinical trial evidence. Semin Dial. 2022; 35 (5): 440–445. doi: 10.1111/sdi.13085.
14. Vernooij RWM, Hockham C, Strippoli G, Green S, Hegbrant J, Davenport A et al. Haemodiafiltration versus haemodialysis for kidney failure: an individual patient data meta-analysis of randomised controlled trials. Lancet. 2024 Oct 25: S0140-6736(24)01859-2. doi: 10.1016/s0140-6736(24)01859-2.
15. Guimarães MGM, Tapioca FPM, Dos Santos NR, Tourinho Ferreira FPDC, Santana Passos LC, Rocha PN. Hemodiafiltration versus Hemodialysis in End-Stage Kidney Disease: A Systematic Review and Meta-Analysis. Kidney Med. 2024; 6 (6): 100829. doi: 10.1016/j.xkme.2024.100829.
16. https://cr.minzdrav.gov.ru/preview-cr/469_3.
17. https://usrds-adr.niddk.nih.gov/2024/end-stage-renal-disease/3-clinical-indicators-and-preventive-care.
18. Amaral S, Hwang W, Fivush B, Neu A, Frankenfield D, Furth S. Serum albumin level and risk for mortality and hospitalization in adolescents on hemodialysis. Clin J Am Soc Nephrol. 2008; 3 (3): 759–767. doi: 10.2215/CJN.02720707.
19. Leon JB, Albert JM, Gilchrist G, Kushner I, Lerner E, Mach S et al. Improving albumin levels among hemodialysis patients: a community-based randomized controlled trial. Am J Kidney Dis. 2006; 48 (1): 28–36. doi: 10.1053/j.ajkd.2006.03.046.
20. Macedo E, Karl B, Lee E, Mehta RL. A randomized trial of albumin infusion to prevent intradialytic hypotension in hospitalized hypoalbuminemic patients. Crit Care. 2021; 25 (1): 18. doi: 10.1186/s13054-020-03441-0.
21. Writing Group for the CKD Prognosis Consortium; Grams ME, Coresh J, Matsushita K, Ballew SH, Sang Y, Surapaneni A et al. Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes: An Individual-Participant Data Meta-Analysis. JAMA. 2023; 330 (13): 1266–1277. doi: 10.1001/jama.2023.17002.
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For citations:
Gautier S.V., Khomyakov S.M., Tsirulnikova O.M., Chebotareva N.V., Kruglov D.N. Status and trends in chronic kidney disease and renal replacement therapy in the Russian Federation: 2024 Report. Annual monitoring by the Center for Excellence in Medical Care in Nephrology at Shumakov National Medical Research Center of Transplantology and Artificial Organs, Moscow, Russian Federation. Russian Journal of Transplantology and Artificial Organs. 2025;27(3):173-203. (In Russ.) https://doi.org/10.15825/1995-1191-2025-3-173-203