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GATED SPECT TO EVALUATE LEFT VENTRICULAR MYOCARDIAL PERFUSION, FUNCTION AND DYSSYNCHRONY FOR RESYNCHRONIZATION THERAPY

https://doi.org/10.15825/1995-1191-2009-2-37-42

Abstract

The study included 15 consecutive patients with heart failure and substantial LV dyssynchrony undergoing CRT. Clinical and phase analysis of gated myocardial perfusion SPECT assessed at baseline, after 2–3 days and after 3–4 months of CRT. The results demonstrated inversely relationship between the response to CRT and the nonviable myocardium. Evaluation of myocardial viability is necessary to considered in the selection process for CRT.

About the Authors

E.N. Ostroumov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


Е.D. Kotina
Saint-Petersburg State University, Saint-Petersburg
Russian Federation


V.V. Slobodianik
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


D.V. Shumakov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


V.V. Tonkoshkurova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


I.Y. Tuniaeva
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


O.V. Chestukchina
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


A.E. Ermolenko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


References

1. Остроумов Е.Н., Честухин В.В., Миронков Б.Л., Покатилов А.А., Миронков А.Б. Возможность улучшения клинического состояния у больных ишемической кардиомиопатией после реваскуляризации // Российский кардиологический журнал. 2006. Внеочередной выпуск. C. 78–82.

2. Abraham W.T., Fisher W.G., Smith A.L. et al. Cardiac resynchronization in chronic heart failure // Engl J Med. 2002. V. 346. P. 1845–1853.

3. Adelstein E.C., Saba S. Scar Burden by Myocardial Perfusion Imaging Predicts Echocardiographic Response to

4. Cardiac Resynchronization Therapy in Ischemic Cardiomyopathy // Am Heart J. 2007. V. 153 (1). P. 105–112.

5. Bax J.J., Bleeker G.B., Marwick T.H. et al. Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy // J Am Coll Cardiol. 2004. V. 44. P. 1834–1840.

6. Birnie D.H., ASL Tang. The problem of non-response to cardiac resynchroniztion therapy // Curr Opin Cardiol. 2006. V. 21. P. 20–26.

7. Boogers M.M., Ji Chen and Bax J.J. Role of nuclear imaging in cardiac resynchronization therapy // Expert Review of Cardiovascular Therapy January. 2009. V. 7. (1). P. 65–72.

8. Brandao S., Ji Chen, Giorgi M.Cl. et al. Phase analysis of gated myocardial perfusion SPECT: A new method to evaluate left ventricular dyssynchrony // J Nucl Med. 2007. V. 48 (Suppl. 2). 234 p.

9. Maruyama A., Hasegawa S., Paul A.K. et al. Myocardial viability assessment with gated SPECT Tc-99m tetrofosmin % wall thickening: comparison with F-18 FDGPET // Ann Nucl Med. 2002. V. 16 (1). P. 25–32.

10. Perrone-Filardi P., Bacharach S.L., Dilsizian V. et al. Regional left ventricular wall thickening. Relation to regional uptake of 18 fl uorodeoxyglucose and 201Tl in patients with chronic coronary artery disease and left ventricular dysfunction // Circulation. 1992. V. 86. P. 1125–1137.

11. Toussaint J.F., Lavergne T., Kerrou K. et al. Basal asynchrony and resynchronization with biventricular pacing predict long-term improvement of LV function in heart failure patients // Pacing Clin Electrophysiol. 2003. V. 26. P. 1815–1823.

12. Vardas P.E. et al. Guidelines for cardiac pacing and cardiac resynchronization therapy // European Heart J. 2007. V. 28. P. 2256–2295.

13. Ypenburg C., Schalij M.J., Bleeker G.B. et al. Extent of Viability to Predict Response to Cardiac Resynchronization

14. Therapy in Ischemic Heart Failure Patients // J Nucl. Med. 2006. V. 47. P. 1565–1570.

15. Ypenburg C., Schalij M.J., Bleeker G.B. et al. Impact of viability and scar tissue on response to cardiac resynchronization

16. therapy in ischaemic heart failure patients // European Heart J. 2007. V. 28. P. 33–41.


Review

For citations:


Ostroumov E., Kotina Е., Slobodianik V., Shumakov D., Tonkoshkurova V., Tuniaeva I., Chestukchina O., Ermolenko A. GATED SPECT TO EVALUATE LEFT VENTRICULAR MYOCARDIAL PERFUSION, FUNCTION AND DYSSYNCHRONY FOR RESYNCHRONIZATION THERAPY. Russian Journal of Transplantology and Artificial Organs. 2009;11(2):37-42. (In Russ.) https://doi.org/10.15825/1995-1191-2009-2-37-42

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ISSN 1995-1191 (Print)