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THE USE OF PLASMAPHERESIS IN THE TREATMENT OF CORONARY ARTERY DISEASE OF TRANSPLANTED HEART AND EVALUATION OF ITS EFFECTIVENESS

https://doi.org/10.15825/1995-1191-2009-2-25-28

Abstract

The paper presents the experience with plasmapheresis in the treatment of сoronary artery disease with drug therapy. 19 recipients at different time after cardiac transplantation with coronary artery disease confi rmed by angiography were treated by therapeutic plasmapheresis courses. The effectiveness was estimated by radioisotope, immunomorphological and laboratory methods. After the course there were increase of regional and local myocardium contractility, increase in left ventricle ejection fraction, reducing intraventricular asynchrony, permission immunocomplex syndrome and lack of local intravascular blood coagulation. Plasmapheresis is considered as a promising method for the impact on the factors contributing to the accelerated nature of the development of coronary arteries lesions in transplanted heart.

About the Authors

N.Z. Meboniya
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


B.N. Morozov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


E.N. Ostroumov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


A.G. Kupriyanova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


N.A. Maksimova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs, Moscow
Russian Federation


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Review

For citations:


Meboniya N., Morozov B., Ostroumov E., Kupriyanova A., Maksimova N. THE USE OF PLASMAPHERESIS IN THE TREATMENT OF CORONARY ARTERY DISEASE OF TRANSPLANTED HEART AND EVALUATION OF ITS EFFECTIVENESS. Russian Journal of Transplantology and Artificial Organs. 2009;11(2):25-28. (In Russ.) https://doi.org/10.15825/1995-1191-2009-2-25-28

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ISSN 1995-1191 (Print)