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Mucormycosis in solid organ transplant recipients (clinical cases and literature review)

https://doi.org/10.15825/1995-1191-2024-3-56-65

Abstract

Mucormycosis is a severe mycotic infection with high mortality among immunocompromised patients. Its in- cidence in solid organ transplant recipients is 2–8% of all invasive fungal infections. In most cases, it occurs in the late posttransplant period. Risk factors in this patient cohort are graft-versus-host disease (GvHD) and use of immunosuppressive drugs. The article describes clinical cases of mucormycosis and analysis of literature data on the problem of invasive mucormycosis in solid organ transplant recipients. It also reviews the main methods of diagnosis and treatment of the disease according to international guidelines.

About the Authors

S. N. Khostelidi
North-Western State Medical University
Russian Federation

Sofya N. Khostelidi

1/28, Santiago de Cuba str., St. Petersburg, 194291



O. P. Kozlova
North-Western State Medical University
Russian Federation

St. Petersburg



E. V. Shagdileeva
North-Western State Medical University
Russian Federation

St. Petersburg



E. V. Semenova
North-Western State Medical University; Leningrad Regional Clinical Hospital
Russian Federation

St. Petersburg



E. M. Kvitko
Children’s Republican Clinical Hospital
Russian Federation

Kazan



A. V. Berdnikova
Children’s Republican Clinical Hospital
Russian Federation

Kazan



R. A. Osokina
Bakulev National Medical Research Center for Cardiovascular Surgery
Russian Federation

Moscow



Yu. L. Avdeenko
North-Western State Medical University
Russian Federation

St. Petersburg



A. E. Taraskina
North-Western State Medical University

St. Petersburg



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Supplementary files

Review

For citations:


Khostelidi S.N., Kozlova O.P., Shagdileeva E.V., Semenova E.V., Kvitko E.M., Berdnikova A.V., Osokina R.A., Avdeenko Yu.L., Taraskina A.E. Mucormycosis in solid organ transplant recipients (clinical cases and literature review). Russian Journal of Transplantology and Artificial Organs. 2024;26(3):56-65. https://doi.org/10.15825/1995-1191-2024-3-56-65

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ISSN 1995-1191 (Print)