Preview

Russian Journal of Transplantology and Artificial Organs

Advanced search

Lung donation after cardiac arrest. Challenges and opportunities. Literature review

https://doi.org/10.15825/1995-1191-2024-1-171-177

Abstract

The global development of transplantology faces several objective obstacles. One of the major ones is widespread organ shortage. This is most pronounced in clinical lung transplantation (LT). The development of this area is directly connected with more intensive development of available donor resources and search for new sources of donor organs that are suitable for transplantation. Along with the existing methods of increasing the number of lungs suitable for transplantation, LT with donation after cardiac death (DCD) is attracting increasing attention. The effectiveness of this approach has been confirmed by the International Society for Heart and Lung Transplantation and deserves more attention from Russian specialists.

About the Authors

I. V. Pashkov
Shumakov National Medical Research Center of Transplantology and Artificial Organs
Russian Federation

1, Shchukinskaya str., Moscow, 123182



M. G. Minina
Shumakov National Medical Research Center of Transplantology and Artificial Organs; Botkin Hospital
Russian Federation

1, Shchukinskaya str., Moscow, 123182



N. V. Grudinin
Shumakov National Medical Research Center of Transplantology and Artificial Organs
Russian Federation

1, Shchukinskaya str., Moscow, 123182



V. K. Bogdanov
Shumakov National Medical Research Center of Transplantology and Artificial Organs
Russian Federation

1, Shchukinskaya str., Moscow, 123182



References

1. Puri V, Patterson GA, Meyers BF. Single versus bilateral lung transplantation: do guidelines exist? Thorac Surg Clin. 2015; 25 (1): 47–54.

2. Slama A, Ghanim B, Klikovits T, Scheed A, Hoda MA, Hoetzenecker K et al. Lobar lung transplantation – is it comparable with standard lung transplantation? Transpl Int. 2014 Sep; 27 (9): 909–916.

3. Artemiou O, Birsan T, Taghavi S, Eichler I, Wisser W, Wolner E, Klepetko W. Bilateral lobar transplantation with the split lung technique. J Thorac Cardiovasc Surg. 1999 Aug; 118 (2): 369–370.

4. Date H. Living-related lung transplantation. J Thorac Dis. 2017 Sep; 9 (9): 3362–3371.

5. Date H, Aoyama A, Hijiya K, Motoyama H, Handa T, Kinoshita H et al. Outcomes of various transplant procedures (single, sparing, inverted) in living-donor lobar lung transplantation. J Thorac Cardiovasc Surg. 2017 Feb; 153 (2): 479–486.

6. Takahagi A, Chen-Yoshikawa TF, Saito M, Okabe R, Gochi F, Yamagishi H et al. Native upper lobe-sparing living-donor lobar lung transplantation maximizes respiratory function of the donor graft. J Heart Lung Transplant. 2019 Jan; 38 (1): 66–72.

7. Bhorade SM, Vigneswaran W, McCabe MA, Garrity ER. Liberalization of donor criteria may expand the donor pool without adverse consequence in lung transplantation. J Heart Lung Transplant. 2000 Dec; 19 (12): 1199–1204.

8. Lardinois D, Banysch M, Korom S, Hillinger S, Rousson V, Boehler A et al. Extended donor lungs: eleven years experience in a consecutive series. Eur J Cardiothorac Surg. 2005 May; 27 (5): 762–767.

9. Noiseux N, Nguyen BK, Marsolais P, Dupont J, Simard L, Houde I et al. Pulmonary recruitment protocol for organ donors: a new strategy to improve the rate of lung utilization. Transplant Proc. 2009 Oct; 41 (8): 3284–3289.

10. Parto S, Shafaghi S, Khoddami-Vishteh HR, Makki SM, Abbasidezfuli A, Daneshvar A et al. Efficacy of recruitment maneuver for improving the brain dead marginal lungs to ideal. Transplant Proc. 2013; 45 (10): 3531–3533.

11. Cypel M, Keshavjee S. Ex vivo lung perfusion. Operative Techniques in Thoracic and Cardiovascular Surgery. 2014; 19 (4): 433–442.

12. Luo Q, Zhu L, Wang Y, Wang L, Lv W, Hu J. The conversional efficacy of ex vivo lung perfusion and clinical outcomes in patients undergoing transplantation of donor lungs by ex vivo lung perfusion: a meta-analysis. Ann Transplant. 2019 Dec 27; 24: 647–660.

13. Chesnokova NP, Ponukalina EV, Bizenkova MN. Molecular-cellular mechanisms of cytotoxic effect of hypoxia. Pathogenesis of hypoxic necrobiosis. Sovremennye naukoemkie tekhnologii. 2006; 7: 32–40.

14. Laubach VE, Sharma AK. Mechanisms of lung ischemia-reperfusion injury. Curr Opin Organ Transplant. 2016 Jun; 21 (3): 246–252.

15. Egan TM, Lambert CJ Jr, Reddick R, Ulicny KS Jr, Keagy BA, Wilcox BR. A strategy to increase the donor pool: use of cadaver lungs for transplantation. Ann Thorac Surg. 1991 Nov; 52 (5): 1113–1120.

16. Ulicny KS Jr, Egan TM, Lambert CJ Jr, Reddick RL, Wilcox BR. Cadaver lung donors: effect of preharvest ventilation on graft function. Ann Thorac Surg. 1993 May; 55 (5): 1185–1191.

17. D’Armini AM, Tom EJ, Roberts CS, Henke DC, Lemasters JJ, Egan TM. When does the lung die? Time course of high energy phosphate depletion and relationship to lung viability after «death». J Surg Res. 1995 Oct; 59 (4): 468–474.

18. Hennington MH, D’Armini AM, Lemasters JJ, Egan TM. Cadaver lungs for transplantation. Effect of ventilation with alveolar gas. Transplantation. 1996 Apr 15; 61 (7): 1009–1014.

19. Guseinov GK, Fetisov VA, Bogomolov DV. Forensic medical evaluation of tanatogenesis in survivors of a craniocerebral injury. Sudebnomeditsinskaya ekspertiza. 2010; 4: 8–9.

20. Rogers FB, Shackford SR, Trevisani GT, Davis JW, Mackersie RC, Hoyt DB. Neurogenic pulmonary edema in fatal and nonfatal head injuries. J Trauma. 1995 Nov; 39 (5): 860–866.

21. Shatalov VI, Schegolev AV, Gritsay AN, Afonchikov VS. Neurogenic pulmonary edema. Messenger of Anesthesiology and Resuscitation. 2018; 15 (1): 55–62.

22. Kootstra G, Daemen JH, Oomen AP. Categories of nonheart-beating donors. Transplant Proc. 1995 Oct; 27 (5): 2893–2894.

23. Reznik ON, Skvortcov AE, Popova OV. Ethical issues of organ donation after cardiac death. Russian Journal of Transplantology and Artificial Organs. 2018; 20 (3): 116–125.

24. Cypel M, Levvey B, Van Raemdonck D, Erasmus M, Dark J, Love R et al. International Society for Heart and Lung Transplantation donation after circulatory death registry report. J Heart Lung Transplant. 2015 Oct; 34 (10): 1278–1282.

25. Van Raemdonck D, Keshavjee S, Levvey B, Cherikh WS, Snell G, Erasmus M et al. Donation after circulatory death in lung transplantation-five-year follow-up from ISHLT Registry. J Heart Lung Transplant. 2019 Dec; 38 (12): 1235–1245.

26. Rodríguez DA, Del Río F, Fuentes ME, Naranjo S, Moradiellos J, Gómez D et al. Lung transplantation with uncontrolled non-heart-beating donors. Transplantation. Donor prognostic factor and immediate evolution post transplant. Arch Bronconeumol. 2011 Aug; 47 (8): 403–409.

27. Gomez-de-Antonio D, Campo-Cañaveral JL, Crowley S, Valdivia D, Cordoba M, Moradiellos J et al. Clinical lung transplantation from uncontrolled non-heart-beating donors revisited. J Heart Lung Transplant. 2012 Apr; 31 (4): 349–53.

28. Miñambres E, Suberviola B, Guerra C, Lavid N, Lassalle M, González-Castro A, Ballesteros MA. Experience of a Maastrich type II non heart beating donor program in a small city: preliminary results. Med Intensiva. 2015 Oct; 39 (7): 433–441.

29. Valenza F, Citerio G, Palleschi A, Vargiolu A, Fakhr BS, Confalonieri A et al. Successful transplantation of lungs from an uncontrolled donor after circulatory death preserved in situ by alveolar recruitment maneuvers and assessed by ex vivo lung perfusion. Am J Transplant. 2016 Apr; 16 (4): 1312–1318.

30. Copeland H, Hayanga JWA, Neyrinck A, MacDonald P, Dellgren G, Bertolotti A et al. Donor heart and lung procurement: a consensus statement. J Heart Lung Transplant. 2020 Jun; 39 (6): 501–517.

31. Moradiellos FJ, Naranjo JM, Córdoba M, Salas C, Gómez D, Campo-Cañaveral JL et al. 90 Clinical lung transplantation after ex vivo evaluation of uncontrolled non heart-beating donors lungs: initial experience. J Heart Lung Transplant. 2011 Apr; 30 (4): S38.

32. Campo-Cañaveral de la Cruz JL, Gómez de Antonio D, Crowley Carrasco S, Valdivia Concha DA, Macías Sotuela L, Naranjo Gómez JM et al. 324 Uncontrolled NonHeart-Beating-Donors (NHBD): Clinical Experience and Results. J Heart Lung Transplant. 2012 Apr; 31 (4): S115–S116.


Supplementary files

Review

For citations:


Pashkov I.V., Minina M.G., Grudinin N.V., Bogdanov V.K. Lung donation after cardiac arrest. Challenges and opportunities. Literature review. Russian Journal of Transplantology and Artificial Organs. 2024;26(1):171-177. https://doi.org/10.15825/1995-1191-2024-1-171-177

Views: 423


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1995-1191 (Print)