PERIOPERATIVE PERIOD FOLLOWING HEART TRANSPLANTATION WITH SEVERE LEFT VENTRICULAR HYPERTROPHY
https://doi.org/10.15825/1995-1191-2012-2-6-14
Abstract
Use donor hearts with left ventricular hypertrophy (LVH) is controversial. This category of heart recipients has increasing risk of early graft failure. We proposed that heart transplantation (HT) with LVH ≥1.5 cm may be successful if performed in selective category patients from alternate transplant list. This study included 10 pati- ents (2 female and 8 male) at the age 26–62 (44 ± 3), who needed urgent HT. This study showed that recipients with LVH ≥1.5 cm demanded more high and long inotropic support with adrenalin and dopamine, more fre- quent use of levosimendan infusion (in 40% of cases) and intraaortic balloon conterpulsation (in 50% of cases). However we didn’t observed any difference in survival rate (90.0% vs 89.0%) and ICU time (4.8 ± 0.6 days vs 4.1 ± 0.4 days) between HT recipients with and without LVH. Our study showed that HT from donor with LVH ≥1.5 cm may be performed in patients, demanding urgent HT, with acceptable early posttransplant results.
About the Authors
V. N. Poptsov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
E. A. Spirina
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
V. V. Pchelnikov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
D. S. Ilyin
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
V. A. Ilyinskiy
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
I. D. Potapenko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
S. G. Uchrenkov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
N. A. Kuguneva
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
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Review
For citations:
Poptsov V.N., Spirina E.A., Pchelnikov V.V., Ilyin D.S., Ilyinskiy V.A., Potapenko I.D., Uchrenkov S.G., Kuguneva N.A. PERIOPERATIVE PERIOD FOLLOWING HEART TRANSPLANTATION WITH SEVERE LEFT VENTRICULAR HYPERTROPHY. Russian Journal of Transplantology and Artificial Organs. 2012;14(2):6-14. (In Russ.) https://doi.org/10.15825/1995-1191-2012-2-6-14
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