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CENTRAL PONTINE MYELINOLYSIS AFTER ORTHOTOPIC LIVER TRANSPLANTATION (TWO CASE REPORTS)

https://doi.org/10.15825/1995-1191-2013-1-89-95

Abstract

Central pontine myelinolysis (CPM) is the rare, but extremely severe complication after orthotopic liver trans- plantation. The reason for CPM is currently not precisely defined. However, the rapid correction of hyponatremia is considered as the main etiological factor. In this paper we present two clinical cases of CPM in patients under- went orthotopic liver transplantation. We also discuss the pathophysiology, epidemiology, clinical presentation, treatment options and preventive measures of CPM. 

About the Authors

A. M. Dzyadzko
Republican Research and Practice Centre «Tissue and Organ Transplantation», Minsk State Clinical Hospital No 9, Minsk, Republic of Belarus


M. L. Katin
Republican Research and Practice Centre «Tissue and Organ Transplantation», Minsk State Clinical Hospital No 9, Minsk, Republic of Belarus


O. O. Rummo
Republican Research and Practice Centre «Tissue and Organ Transplantation», Minsk State Clinical Hospital No 9, Minsk, Republic of Belarus


A. E. Shcherba
Republican Research and Practice Centre «Tissue and Organ Transplantation», Minsk State Clinical Hospital No 9, Minsk, Republic of Belarus


E. O. Santotsky
Republican Research and Practice Centre «Tissue and Organ Transplantation», Minsk State Clinical Hospital No 9, Minsk, Republic of Belarus


A. F. Minov
Republican Research and Practice Centre «Tissue and Organ Transplantation», Minsk State Clinical Hospital No 9, Minsk, Republic of Belarus


M. Y. Gurova
Republican Research and Practice Centre «Tissue and Organ Transplantation», Minsk State Clinical Hospital No 9, Minsk, Republic of Belarus


O. A. Chugunova
Republican Research and Practice Centre «Tissue and Organ Transplantation», Minsk State Clinical Hospital No 9, Minsk, Republic of Belarus


Y. V. Slobodin
Republican Research and Practice Centre «Tissue and Organ Transplantation», Minsk State Clinical Hospital No 9, Minsk, Republic of Belarus


S. M. Zubritsky
Republican Research and Practice Centre «Tissue and Organ Transplantation», Minsk State Clinical Hospital No 9, Minsk, Republic of Belarus


L. L. Avdei
Minsk Consulting and Diagnostic Center, Minsk, Republic of Belarus


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Review

For citations:


Dzyadzko A.M., Katin M.L., Rummo O.O., Shcherba A.E., Santotsky E.O., Minov A.F., Gurova M.Y., Chugunova O.A., Slobodin Y.V., Zubritsky S.M., Avdei L.L. CENTRAL PONTINE MYELINOLYSIS AFTER ORTHOTOPIC LIVER TRANSPLANTATION (TWO CASE REPORTS). Russian Journal of Transplantology and Artificial Organs. 2013;15(1):89-95. (In Russ.) https://doi.org/10.15825/1995-1191-2013-1-89-95

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ISSN 1995-1191 (Print)