Re-interventions after the Ross procedure: reasons, technical approaches, immediate outcomes
https://doi.org/10.15825/1995-1191-2021-1-101-111
Abstract
Re-interventions after pulmonary autograft aortic valve replacement (Ross procedure) may be associated with dysfunction of the neoaortic, neopulmonary, or both operated valves. Late dysfunction, other than infective endocarditis, is associated with underlying conditions, technical errors, and unsuitable pulmonary trunk replacement materials. Re-interventions are technically complex, while tactical approaches have not been definitively formulated. Objective: to analyze re-interventions in patients after Ross procedure, technical approaches and immediate outcomes. Material and methods. Between 2001 and 2019, 14 patients were reoperated upon within 2 days to 21 years after primary Ross procedure. Early prosthetic endocarditis (2) and technical errors (1) were the reasons for early postoperative re-intervention. Neoaortic valve insufficiency (7), including pulmonary valve dysfunction (2), pulmonary valve degeneration (2), pulmonary prosthetic valve endocarditis (1), aortic, pulmonary and mitral valve endocarditis (1) were the reasons for late postoperative re-intervention. Based on the lesion volume, neoaortic valve replacement (3), neoaortic root replacement (6), including pulmonary valve/trunk replacement (8), and pulmonary trunk stenting (2) were performed. Results. In-hospital mortality was 7.1%. One patient died of early endocarditis after primary procedure. The postoperative period for the remaining patients was uneventful. Microscopic examination of the neoaorta revealed fragmentation of elastic fibers and rearrangement of tissue histoarchitectonics. In the pulmonary position, the aortic allograft and stentless xenograft had severe calcification and valve stenosis. Conclusions. Neoaortic valve insufficiency associated with cusp prolapse and neoaortic root dilatation may be the reasons for re-interventions after the Ross procedure. The second reason for re-interventions is valve graft dysfunction in the pulmonary trunk position. Elective reoperations on the neoaortic root and/or lung graft, despite the large volume, can be performed with low mortality and morbidity. Aortic allografts and xenografts for reconstruction of the right ventricular outflow tract (RVOT) is unjustified due to early and more severe dysfunction compared to pulmonary allograft.
About the Authors
R. M. MuratovRussian Federation
135, Rubliovskoe sh., Moskva, 121552.
M. I. Fedoseykina
Russian Federation
Maria Fedoseykina.
135, Rubliovskoe sh., Moskva, 121552.
Phone: (977) 387-50-55
D. A. Titov
Russian Federation
135, Rubliovskoe sh., Moskva, 121552.
D. V. Britikov
Russian Federation
135, Rubliovskoe sh., Moskva, 121552.
G. A. Khugaev
Russian Federation
135, Rubliovskoe sh., Moskva, 121552.
References
1. Tanaka H, Okita Y, Kasegawa H, Takamoto S, Tabayashi K, Yagihara T et al. The fate of bioprostheses in middle-aged patients: the Japanese experience. J Heart Valve Dis. 2010; 19 (5): 561-567.
2. Chan V, Malas T, Lapierre H, Boodhwani M, Lam BK, Rubens FD et al. Reoperation of left heart valve bioprostheses according to age at implantation. Circulation. 2011; 124 (11 Suppl): 75-80. doi: 10.1161/CIRCULATIONAHA.110.011973.
3. Klieverik LM, Noorlander M, Takkenberg JJ, Kappetein AP, Bekkers JA, van Herwerden LA et al. Outcome after aortic valve replacement in young adults: is patient profile more important than prosthesis type? J Heart Valve Dis. 2006; 15 (4): 479-487.
4. Andreas M, Wiedemann D, Seebacher G, Rath C, Aref T, Rosenhek R et al. The Ross procedure offers excellent survival compared with mechanical aortic valve replacement in a real-world setting. Eur J Cardiothorac Surg. 2014; 46 (3): 409-414. doi: 10.1093/ejcts/ezt663.
5. Brown JW, Patel PM, Ivy Lin JH, Habib AS, Rodefeld MD, Turrentine MW. Ross Versus Non-Ross Aortic Valve Replacement in Children: A 22-Year Single Institution Comparison of Outcomes. Ann Thorac Surg. 2016; 101 (5): 1804-1810. doi: 10.1016/j.athoracsur.2015.12.076.
6. Etnel JR, Elmont LC, Ertekin E, Mokhles MM, Heuvelman HJ, Roos-Hesselink JW et al. Outcome after aortic valve replacement in children: A systematic review and meta-analysis. J Thorac Cardiovasc Surg. 2016: 151 (1): 143-152. e1-3. doi: 10.1016/j.jtcvs.2015.09.083.
7. Elkins RC, Thompson DM, Lane MM, Elkins CC, Peyton MD. Ross operation: 16-year experience. J Thorac Cardiovasc Surg. 2008; 136 (3): 623-630. e1-5. doi: 10.1016/j.jtcvs.2008.02.080.
8. Aicher D, Holz A, Feldner S, Kollner V, Schafers HJ. Quality of life after aortic valve surgery: replacement versus reconstruction. J Thorac Cardiovasc Surg. 2011; 142 (2): 19-24. doi: 10.1016/j.jtcvs.2011.02.006.
9. Karaskov AM, Bogachev-Prokophiev AV, Lenko EV, Demin II. Lethality predictors in adults undergoing Ross procedure: analysis of 760 operations. Patologiya krovoobrashcheniya i kardiokhirurgiya. 2017; 21 (1): 73-80. doi: 10.21688-1681-3472-2017-1-73-80. (In Russ. English abstrac).
10. Somerville J, Ross D. Homograft replacement of aortic root with reimplantation of coronary arteries. Results after one to five years. Br Heart J. 1982; 47 (5): 473-482. doi: 10.1136/hrt.47.5.473.
11. Nappi F, Fraldi M, Spadaccio C, Carotenuto AR, Montagnani S, Castaldo C et al. Biomechanics drive histological wall remodeling of neoaortic root: A mathematical model to study the expression levels of ki 67, metalloprotease, and apoptosis transition. J Biomed Mater Res A. 2016; 104: 2785-2793. doi: 10.1002/jbm.a.35820.
12. Mookhoek A, Krishnan K, Chitsaz S, Kuang H, Ge L, Schoof PH et al. Biomechanics of failed pulmonary autografts compared with normal pulmonary roots. Ann Thorac Surg. 2016; 102 (6): 1996-2002. doi: 10.1016/j.athoracsur.2016.05.010.
13. Skillington PD, Mokhles MM, Takkenberg JJ, Larobina M, O'Keefe M, Wynne R et al. The Ross procedure using autologous support of the pulmonary autograft: techniques and late results. J Thorac Cardiovasc Surg. 2015; 149: 46-52. doi: 10.1016/j.jtcvs.2014.08.068.
14. Carrel T, Kadner A. Long-term clinical and imaging follow-up after reinforced pulmonary autograft Ross procedure. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2016; 19: 59-62. doi: 10.1053/j.pcsu.2015.11.005.
15. Carr-White GS, Afoke A, Birks EJ, Hughes S, O'Halloran A, Glennen S et al. Aortic root characteristics of human pulmonary autografts. Circulation. 2000. 7; 102 (19 Suppl 3): III15-21.
16. David TE, Woo A, Armstrong S, Maganti M. When is the Ross operation a good option to treat aortic valve disease? J Thorac Cardiovasc Surg. 2010; 139 (1): 68-73; discussion 73-75. doi: 10.1016/j.jtcvs.2009.09.053.
17. David TE, David C, Woo A, Manlhiot C. The Ross procedure: outcomes at 20 years J Thorac Cardiovasc Surg. 2014. 147 (1): 85-93. doi: 10.1016/j.jtcvs.2013.08.007.
18. Weimar T, Charitos EI, Liebrich M, Roser D, Tzanavaros I, Doll N et al. Quo vadis pulmonary autograft-the ross procedure in its second decade: a single-center experience in 645 patients. Ann Thorac Surg. 2014; 97 (1): 167-174. doi: 10.1016/j.athoracsur.2013.07.078.
19. Albert JD, Bishop DA, Fullerton DA, Campbell DN, Clarke DR. Conduit reconstruction of the right ventricular outflow tract: lessons learned in a twelve-year experience. J Thorac Cardiovasc Surg. 1993; 106 (2): 228-236.
20. Yankah AC, Alexi-Meskhishvili V, Weng Y, Berger F, Lange P, Hetzer R. Performance of aortic and pulmonary homografts in the right ventricular outflow tract in children. J Heart Valve Dis. 1995; 4 (4): 392-395.
21. Andreas M, Seebacher G, Reida E, Wiedemann D, Pees C, Rosenhek R et al. A single-center experience with the ross procedure over 20 years. Ann Thorac Surg. 2014; 97 (1): 182-188. doi: 10.1016/j.athoracsur.2013.08.020.
22. Bell D, Prabhu S, Betts KS, Chen Y, Radford D, Whight C et al. Long-term performance of homografts versus stented bioprosthetic valves in the pulmonary position in patients aged 10-20 years. Eur J Cardiothorac Surg. 2018; 54 (5): 946-952. doi: 10.1093/ejcts/ezy149.
23. Costa FD, Etnel JR, Charitos EI, Sievers HH, Stierle U, Fornazari D et al. Decellularized Versus Standard Pulmonary Allografts in the Ross Procedure: Propensity-Matched Analysis. Ann Thorac Surg. 2018; 105 (4): 1205-1213. doi: 10.1016/j.athoracsur.2017.09.057.
24. Bibevski S, Ruzmetov M, Fortuna RS, Turrentine MW, Brown JW, Ohye RG. Performance of synergraft decellularized pulmonary allografts compared with standard cryopreserved allografts: results from multiinstitutional data. Ann Thorac Surg. 2017; 103 (3): 869-874. doi: 10.1016/j.athoracsur.2016.07.068.
25. Matsonashvili TR, Muratov RM, Babenko SI, Sachkov AS Serov RA, Britikov DV. Degenerative changes in allograft the long term after the operation. Possible causes of dysfunction and ways of extending the length of calligraphy service. Byulleten' nauchnogo tsentra serdechno-sosudistoy khirurgii im. A.N. Bakuleva (The Bulletin of A.N. Bakoulev Scientific Center for Cardiovascular Surgery. Cardiovascular diseases, Russian journal). 2013; 14 (3): 131. (in Russ. English abstrac).
26. Jassar AS, Bavaria JE, Szeto WY, Moeller PJ, Maniaci J, Milewski RK et al. Graft selection for aortic root replacement in complex active endocarditis: does it matter? Ann Thorac Surg. 2012; 93 (2): 480-487. doi: 10.1016/j.athoracsur.2011.09.074.
27. Kim JB, Ejiofor JI, Yammine M, Camuso JM, Walsh CW, Ando M et al. Are homografts superior to conventional prosthetic valves in the setting of infective endocarditis involving the aortic valve? J Thorac Cardiovasc Surg. 2016; 151 (5): 1239-1246, 1248. e1-2. doi: 10.1016/j.jtcvs.2015.12.061.
28. Suleymanov BR, Muratov RM, Britikov DV, Soboleva NN, Titov DA. The use of allo- and autografts (Ross procedure) in active infective endocarditis with the aortic root destruction. Annaly khirurgii (Annals of Surgery, Russian journal). 2016; 21 (3): 180-186. (in Russ. English abstrac). doi: 10.18821/1560-9502-2016-21-3-180-186.
29. Fedoseykina MI, Titov DA, Britikov DV, Babenko SI, Muratov RM. Results of the use of allograft and pulmonary autograft (Ross procedure) in active infective aortic valve endocarditis in children. Bulletin of A.N. Bakoulev Scientific Center for Cardiovascular Surgery. Cardiovascular diseases. 2019; 20 (11-12): 986-995. (in Russ. English abstrac). doi: 10.24022/1810-06942019-20-11-12-986-995.
30. Klieverik L, Yacoub M, Edwards S, Bekkers J, Roos-Hesselink J, Kappetein A et al. Surgical treatment of active native aortic valve endocarditis with allografts and mechanical prostheses. Ann Thorac Surg. 2009; 88 (6): 1814-1821. doi: 10.1016/j.athoracsur.2009.08.019.
31. Elgalad A, Arafat A, Elshazly T, Elkahwagy M, Fawzy H, Wahby E et al. Surgery for Active Infective Endocarditis of the Aortic Valve With Infection Extending Beyond the Leaflets. Heart Lung Circ. 2019; 28 (7): 1112-1120. doi: 10.1016/j.hlc.2018.05.200.
Review
For citations:
Muratov R.M., Fedoseykina M.I., Titov D.A., Britikov D.V., Khugaev G.A. Re-interventions after the Ross procedure: reasons, technical approaches, immediate outcomes. Russian Journal of Transplantology and Artificial Organs. 2021;23(1):101-111. https://doi.org/10.15825/1995-1191-2021-1-101-111