Preview

Вестник трансплантологии и искусственных органов

Расширенный поиск

Роль эндоваскулярных и эндобилиарных методов в лечении осложнений после трансплантации печени

https://doi.org/10.15825/1995-1191-2020-4-140-148

Полный текст:

Аннотация

Трансплантация печени является признанным методом лечения пациентов с терминальной стадией заболеваний печени или острой печеночной недостаточностью. Однако сосудистые осложнения, такие как стеноз и/или тромбоз печеночной артерии, стеноз воротной вены трансплантата и билиодигестивные стриктуры, после трансплантации печени все еще часто встречаемы, несмотря на улучшения и инновации в хирургических методах. Данные осложнения могут приводить к повреждениям трансплантата или даже к летальному исходу. Этиология данных осложнений является многофакторной. Хотя малоинвазивная интервенционная радиология для лечения данных осложнений после трансплантации печени является опциональным вариантом лечения, существует достаточно малое количество проведенных исследований данного метода лечения.

Об авторах

С. В. Готье
ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России; ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова» Минздрава России (Сеченовский университет)
Россия
Москва



М. А. Восканов
ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России
Россия

123182, Москва, ул. Щукинская, д. 1

Тел. (915) 230-76-10





А. Р. Монахов
ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России; ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова» Минздрава России (Сеченовский университет)
Россия
Москва



К. О. Сёмаш
ФГБУ «Национальный медицинский исследовательский центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России
Россия
Москва



Список литературы

1. Kelly DA, Bucuvalas JC, Alonso EM et al. Long-term medical management of the pediatric patient after liver transplantation: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation. Liver Transpl. 2013; 19 (8): 798–825. doi: 10.1002/lt.23697.

2. Milne JS. Surgical Instruments in Greek and Roman Times. Oxford: At the Clarendon Press, 1907. 179.

3. Cournand A. Cardiac catheterization; development of the technique, its contributions to experimental medicine, and its initial applications in man. Acta Med Scand Suppl. 1975; 579: 3–32.

4. Fye WB. Coronary arteriography – it took a long time! Circulation. 1984; 70 (5): 781–787. doi: 10.1161/01.cir.70.5.781.

5. Рожченко ЛВ, Иванов АЮ, Горощенко СА, Благоразумова ГП, Христофорова МИ. Развитие сосудистой хирургии в РНХИ им. проф. А.Л. Поленова (к 50-летнему юбилею отделения хирургии сосудов головного мозга РНХИ им. проф. А.Л. Поленова). Российский нейрохирургический журнал имени профессора А.Л. Поленова. 2017; 9 (1): 5–10.

6. Meyer JA. Werner Forssmann and catheterization of the heart, 1929. Ann Thorac Surg. 1990; 49 (3): 497–499. doi: 10.1016/0003-4975(90)90272-8.

7. Seldinger SI. Catheter replacement of the needle in percutaneous arteriography. A new technique. Acta Radiol Suppl (Stockholm). 2008; 434: 47–52. doi: 10.1080/02841850802133386.

8. Sones FM, Shirey EK. Cine coronary arteriography. Modern concepts of cardiovascular disease. 1962; 58: 1018–1019.

9. Петросян ЮС, Зингерман ЛС. Коронарография. Медицина, 1974. 152.

10. Barton M, Grüntzig J, Husmann M, Rösch J. Balloon Angioplasty – The Legacy of Andreas Grüntzig, M.D. (1939–1985). Front Cardiovasc Med. 2014 Dec 29; 1: 15. doi: 10.3389/fcvm.2014.00015. PMID: 26664865; PMCID: PMC4671350.

11. Сорокина ТС. История медицины. 8-е изд. стер. М.: Академия, 2008. 560 с. ISBN 978-5-7695-5781-1.

12. Bjerkvik S, Vatne K, Mathisen O, Søreide O. Percutaneous revascularization of postoperative hepatic artery thrombosis in a liver transplant. Transplantation. 1995; 59 (12): 1746–1748. doi: 10.1097/00007890-199506270-00021.

13. Hidalgo EG, Abad J, Cantarero JM et al. High-dose intra-arterial urokinase for the treatment of hepatic artery thrombosis in liver transplantation. Hepatogastroenterology. 1989; 36 (6): 529–532.

14. Olcott EW, Ring EJ, Roberts JP, Ascher NL, Lake JR, Gordon RL. Percutaneous transhepatic portal vein angioplasty and stent placement after liver transplantation: early experience. J Vasc Interv Radiol. 1990; 1 (1): 17–22. doi: 10.1016/s1051-0443(90)72496-7.

15. Raby N, Karani J, Thomas S, O’Grady J, Williams R. Stenoses of vascular anastomoses after hepatic transplantation: treatment with balloon angioplasty. AJR Am J Roentgenol. 1991; 157 (1): 167–171. doi: 10.2214/ajr.157.1.1828649.

16. Schwarzenberg SJ, Sharp HL, Payne WD et al. Biliary stricture in living-related donor liver transplantation: management with balloon dilation. Pediatr Transplant. 2002; 6 (2): 132–135. doi: 10.1034/j.1399-3046.2002.01053.x.

17. Bekker J, Ploem S, de Jong KP. Early hepatic artery thrombosis after liver transplantation: a systematic review of the incidence, outcome and risk factors. Am J Transplant. 2009; 9 (4): 746–757. doi: 10.1111/j.1600-6143.2008.02541.x.

18. Chen J, Weinstein J, Black S, Spain J, Brady PS, Dowell JD. Surgical and endovascular treatment of hepatic arterial complications following liver transplant. Clin Transplant. 2014; 28 (12): 1305–1312. doi: 10.1111/ctr.12431.

19. Yamada N, Sanada Y, Hirata Y et al. Selection of living donor liver grafts for patients weighing 6 kg or less. Liver Transpl. 2015; 21 (2): 233–238. doi: 10.1002/lt.24048.

20. Li JJ, Zu CH, Li SP, Gao W, Shen ZY, Cai JZ. Effect of graft size matching on pediatric living-donor liver transplantation at a single center. Clin Transplant. 2018; 32 (1): 10.1111/ctr.13160. doi: 10.1111/ctr.13160.

21. Uchida Y, Sakamoto S, Egawa H et al. The impact of meticulous management for hepatic artery thrombosis on long-term outcome after pediatric living donor liver transplantation. Clin Transplant. 2009; 23 (3): 392–399. doi: 10.1111/j.1399-0012.2008.00924.x.

22. Oberkofler CE, Reese T, Raptis DA et al. Hepatic artery occlusion in liver transplantation: What counts more, the type of reconstruction or the severity of the recipient’s disease? Liver Transpl. 2018; 24 (6): 790–802. doi: 10.1002/lt.25044.

23. Oh CK, Pelletier SJ, Sawyer RG et al. Uni- and multivariate analysis of risk factors for early and late hepatic artery thrombosis after liver transplantation. Transplantation. 2001; 71 (6): 767–772. doi: 10.1097/00007890-200103270-00014.

24. Desai CS, Sharma S, Gruessner A, Fishbein T, Kaufman S, Khan KM. Effect of small donor weight and donor-recipient weight ratio on the outcome of liver transplantation in children. Pediatr Transplant. 2015; 19 (4): 366–370. doi: 10.1111/petr.12459.

25. Gunsar F, Rolando N, Pastacaldi S et al. Late hepatic artery thrombosis after orthotopic liver transplantation. Liver Transpl. 2003; 9 (6): 605–611. doi: 10.1053/jlts.2003.50057.

26. Valente JF, Alonso MH, Weber FL, Hanto DW. Late hepatic artery thrombosis in liver allograft recipients is associated with intrahepatic biliary necrosis. Transplantation. 1996; 61 (1): 61–65. doi: 10.1097/00007890-199601150-00013.

27. Guarrera JV, Sinha P, Lobritto SJ, Brown RS Jr, Kinkhabwala M, Emond JC. Microvascular hepatic artery anastomosis in pediatric segmental liver transplantation: microscope vs loupe. Transpl Int. 2004; 17 (10): 585–588. doi: 10.1007/s00147-004-0782-8.

28. Carnevale FC, de Tarso Machado A, Moreira AM et al. Long-term results of the percutaneous transhepatic venoplasty of portal vein stenoses after pediatric liver transplantation. Pediatr Transplant. 2011; 15 (5): 476–481. doi: 10.1111/j.1399-3046.2011.01481.x.

29. Backes AN, Gibelli NE, Tannuri AC et al. Hepatic artery graft in pediatric liver transplantation: single-center experience with 58 cases. Transplant Proc. 2011; 43 (1): 177–180. doi: 10.1016/j.transproceed.2010.11.006.

30. Duffy JP, Hong JC, Farmer DG et al. Vascular complications of orthotopic liver transplantation: experience in more than 4,200 patients. J Am Coll Surg. 2009; 208 (5): 896–905. doi: 10.1016/j.jamcollsurg.2008.12.032.

31. Julka KD, Lin TS, Chen CL, Wang CC, Komorowski AL. Reconstructing single hepatic artery with two arterial stumps: biliary complications in pediatric living donor liver transplantation. Pediatr Surg Int. 2014; 30 (1): 39–46. doi: 10.1007/s00383-013-3436-z.

32. Seda-Neto J, Antunes da Fonseca E, Pugliese R et al. Twenty Years of Experience in Pediatric Living Donor Liver Transplantation: Focus on Hepatic Artery Reconstruction, Complications, and Outcomes. Transplantation. 2016; 100 (5): 1066–1072. doi: 10.1097/TP.0000000000001135.

33. Miraglia R, Maruzzelli L, Caruso S et al. Minimally invasive endovascular and biliary treatments of children with acute hepatic artery thrombosis following liver transplantation. Pediatr Radiol. 2014; 44 (1): 94–102. doi: 10.1007/s00247-013-2772-4.

34. Segel MC, Zajko AB, Bowen A et al. Hepatic artery thrombosis after liver transplantation: radiologic evaluation. AJR Am J Roentgenol. 1986; 146 (1): 137–141. doi: 10.2214/ajr.146.1.137.

35. Hashikura Y, Kawasaki S, Okumura N et al. Prevention of hepatic artery thrombosis in pediatric liver transplantation. Transplantation. 1995; 60 (10): 1109–1112. doi: 10.1097/00007890-199511270-00009.

36. Piardi T, Lhuaire M, Bruno O et al. Vascular complications following liver transplantation: A literature review of advances in 2015. World J Hepatol. 2016; 8 (1): 36–57. doi: 10.4254/wjh.v8.i1.36.

37. Uller W, Knoppke B, Schreyer AG et al. Interventional radiological treatment of perihepatic vascular stenosis or occlusion in pediatric patients after liver transplantation. Cardiovasc Intervent Radiol. 2013; 36 (6): 1562–1571. doi: 10.1007/s00270-013-0595-1.

38. Liao FM, Chang MH, Ho MC et al. Resistance index of hepatic artery can predict anastomotic biliary complications after liver transplantation in children. J Formos Med Assoc. 2019; 118 (1 Pt 2): 209–214. doi: 10.1016/j.jfma.2018.03.014.

39. Yanaga K, Lebeau G, Marsh JW et al. Hepatic artery reconstruction for hepatic artery thrombosis after orthotopic liver transplantation. Arch Surg. 1990; 125 (5): 628–631. doi: 10.1001/archsurg.1990.01410170076016.

40. Sanada Y, Katano T, Hirata Y et al. Interventional radiology treatment for vascular and biliary complications following pediatric living donor liver transplantation – a retrospective study. Transpl Int. 2018; 31 (11): 1216–1222. doi: 10.1111/tri.13285.

41. Langer R, Langer M, Neuhaus P, Scholz A, Felix R. Angiographische Diagnostik bei Lebertransplantation. Teil II: Angiographie nach Transplantation [Angiographic diagnosis in liver transplantation. II: Angiography after transplantation]. Digitale Bilddiagn. 1990; 10 (3–4): 92–96.

42. Cheng YF, Ou HY, Tsang LL et al. Vascular stents in the management of portal venous complications in living donor liver transplantation [published correction appears in Am J Transplant. 2011 Jan; 11 (1): 186]. Am J Transplant. 2010; 10 (5): 1276–1283. doi: 10.1111/j.1600-6143.2010.03076.x.

43. Saad WE, Davies MG, Sahler L et al. Hepatic artery stenosis in liver transplant recipients: primary treatment with percutaneous transluminal angioplasty. J Vasc Interv Radiol. 2005; 16 (6): 795-805. doi: 10.1097/01.RVI.0000156441.12230.13.

44. Saad WE. Management of nonocclusive hepatic artery complications after liver transplantation. Tech Vasc Interv Radiol. 2007; 10 (3): 221–232. doi: 10.1053/j.tvir.2007.09.016.

45. Jurim O, Csete M, Gelabert HA et al. Reduced-size grafts – the solution for hepatic artery thrombosis after pediatric liver transplantation? J Pediatr Surg. 1995; 30 (1): 53–55. doi: 10.1016/0022-3468(95)90609-6.

46. Funaki B, Rosenblum JD, Leef JA et al. Percutaneous treatment of portal venous stenosis in children and adolescents with segmental hepatic transplants: long-term results. Radiology. 2000; 215 (1): 147– 151. doi: 10.1148/radiology.215.1.r00ap38147.

47. Cheng YF, Ou HY, Tsang LL et al. Vascular stents in the management of portal venous complications in living donor liver transplantation [published correction appears in Am J Transplant. 2011 Jan; 11 (1): 186]. Am J Transplant. 2010; 10 (5): 1276–1283. doi: 10.1111/j.1600-6143.2010.03076.x.

48. de Ville de Goyet J, Lo Zupone C, Grimaldi C et al. Meso-Rex bypass as an alternative technique for portal vein reconstruction at or after liver transplantation in children: review and perspectives. Pediatr Transplant. 2013; 17 (1): 19–26. doi: 10.1111/j.1399-3046.2012.01784.x.

49. Rawal N, Yazigi N. Pediatric Liver Transplantation. Pediatr Clin North Am. 2017; 64 (3): 677–684. doi: 10.1016/j.pcl.2017.02.003.

50. Umehara M, Narumi S, Sugai M et al. Hepatic venous outflow obstruction in living donor liver transplantation: balloon angioplasty or stent placement? Transplant Proc. 2012; 44 (3): 769–771. doi: 10.1016/j.transproceed.2012.01.048.

51. Seu P, Shackleton CR, Shaked A et al. Improved results of liver transplantation in patients with portal vein thrombosis. Arch Surg. 1996; 131 (8): 840–845. doi: 10.1001/archsurg.1996.01430200050009.

52. Nosaka S, Isobe Y, Kasahara M et al. Recanalization of post-transplant late-onset long segmental portal vein thrombosis with bidirectional transhepatic and transmesenteric approach. Pediatr Transplant. 2013; 17 (2): E71–E75. doi: 10.1111/petr.12050.

53. Sanada Y, Kawano Y, Mizuta K et al. Strategy to prevent recurrent portal vein stenosis following interventional radiology in pediatric liver transplantation. Liver Transpl. 2010; 16 (3): 332–339. doi: 10.1002/lt.21995.

54. Baccarani U, Gasparini D, Risaliti A et al. Percutaneous mechanical fragmentation and stent placement for the treatment of early posttransplantation portal vein thrombosis. Transplantation. 2001; 72 (9): 1572–1582. doi: 10.1097/00007890-200111150-00016.

55. Sakamoto S, Nakazawa A, Shigeta T et al. Devastating outflow obstruction after pediatric split liver transplantation. Pediatr Transplant. 2013; 17 (1): E25–E28. doi: 10.1111/j.1399-3046.2012.01761.x.

56. Bertram H, Pfister ED, Becker T, Schoof S. Transsplenic endovascular therapy of portal vein stenosis and subsequent complete portal vein thrombosis in a 2-year-old child. J Vasc Interv Radiol. 2010; 21 (11): 1760–1764. doi: 10.1016/j.jvir.2010.06.025.

57. Shibata T, Itoh K, Kubo T et al. Percutaneous transhepatic balloon dilation of portal venous stenosis in patients with living donor liver transplantation. Radiology. 2005; 235 (3): 1078–1083. doi: 10.1148/radiol.2353040489.

58. Ko GY, Sung KB, Yoon HK et al. Endovascular treatment of hepatic venous outflow obstruction after living-donor liver transplantation. J Vasc Interv Radiol. 2002; 13 (6): 591–599. doi: 10.1016/s1051-0443(07)61652-2.

59. Katano T, Sanada Y, Hirata Y et al. Endovascular stent placement for venous complications following pediatric liver transplantation: outcomes and indications. Pediatr Surg Int. 2019; 35 (11): 1185–1195. doi: 10.1007/s00383-019-04551-9.

60. Shim DJ, Ko GY, Sung KB, Gwon DI, Ko HK. LongTerm Outcome of Portal Vein Stent Placement in Pediatric Liver Transplant Recipients: A Comparison with Balloon Angioplasty. J Vasc Interv Radiol. 2018; 29 (6): 800–808. doi: 10.1016/j.jvir.2017.11.019.

61. Anderson CD, Turmelle YP, Darcy M et al. Biliary strictures in pediatric liver transplant recipients – early diagnosis and treatment results in excellent graft outcomes. Pediatr Transplant. 2010; 14 (3): 358–363. doi: 10.1111/j.1399-3046.2009.01246.x.

62. Feier FH, Chapchap P, Pugliese R et al. Diagnosis and management of biliary complications in pediatric living donor liver transplant recipients. Liver Transpl. 2014; 20 (8): 882–892. doi: 10.1002/lt.23896.

63. Sunku B, Salvalaggio PR, Donaldson JS et al. Outcomes and risk factors for failure of radiologic treatment of biliary strictures in pediatric liver transplantation recipients. Liver Transpl. 2006; 12 (5): 821–826. doi: 10.1002/lt.20712.

64. Darius T, Rivera J, Fusaro F et al. Risk factors and surgical management of anastomotic biliary complications after pediatric liver transplantation. Liver Transpl. 2014; 20 (8): 893–903. doi: 10.1002/lt.23910.

65. Feier FH, Seda-Neto J, da Fonseca EA et al. Analysis of factors Associated with biliary complications in children after liver transplantation. Transplantation. 2016; 100 (9): 1944–1954. doi: 10.1097/TP.0000000000001298.

66. Kinner S, Dechêne A, Paul A et al. Detection of biliary stenoses in patients after liver transplantation: is there a different diagnostic accuracy of MRCP depending on the type of biliary anastomosis? Eur J Radiol. 2011; 80 (2): e20–e28. doi: 10.1016/j.ejrad.2010.06.003.

67. Seehofer D, Eurich D, Veltzke-Schlieker W, Neuhaus P. Biliary complications after liver transplantation: old problems and new challenges. Am J Transplant. 2013; 13 (2): 253–265. doi: 10.1111/ajt.12034.

68. Belenky A, Mor E, Bartal G et al. Transhepatic balloon dilatation of early biliary strictures in pediatric liver transplantation: successful initial and mid-term outcome. Cardiovasc Intervent Radiol. 2004; 27 (5): 491–494. doi: 10.1007/s00270-003-2675-0.

69. Miraglia R, Maruzzelli L, Tuzzolino F, Indovina PL, Luca A. Radiation exposure in biliary procedures performed to manage anastomotic strictures in pediatric liver transplant recipients: comparison between radiation exposure levels using an image intensifier and a flat-panel detector-based system. Cardiovasc Interv Radiol. 2013; 36 (6): 1670–1676.


Для цитирования:


Готье С.В., Восканов М.А., Монахов А.Р., Сёмаш К.О. Роль эндоваскулярных и эндобилиарных методов в лечении осложнений после трансплантации печени. Вестник трансплантологии и искусственных органов. 2020;22(4):140-148. https://doi.org/10.15825/1995-1191-2020-4-140-148

For citation:


Gautier S.V., Voskanov M.A., Monakhov A.R., Semash K.O. The role of endovascular and endobiliary methods in the treatment of post-liver transplant complications. Russian Journal of Transplantology and Artificial Organs. 2020;22(4):140-148. (In Russ.) https://doi.org/10.15825/1995-1191-2020-4-140-148

Просмотров: 61


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 1995-1191 (Print)
ISSN 2412-6160 (Online)