CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATION
https://doi.org/10.15825/1995-1191-2012-1-19-26
Abstract
Biochemical markers of bone formation [osteocalcin (OC), N-terminal propeptid of type 1 procollagen (P1NP), bone isoferment of alkaline phosphatase (BALP)] were estimated in 34 recipients after liver transplantation. Three types of deviation have been demonstrated: combination elevated circulating levels OC and P1NP with normal levels BALP in recipients without clinical postoperative complication; combination lower levels OC and BALP with normal levels P1NP in recipients as a result of corticosteroid therapy prior/ following transplantation; superior levels P1NP with normal levels OC and BALP which results excessive accumulation hepatic collagen formation in recipients with postoperative clinical complication.
About the Authors
V.P. Buzulina
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
I.A. Pronchenko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
I.P. Yermakova
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
M.N. Kornilov
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
E.B. Yaroshenko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
D.S. Mnatsakanyan
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
T.K. Koliashvili
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
N.P. Shmerko
Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Buzulina V., Pronchenko I., Yermakova I., Kornilov M., Yaroshenko E., Mnatsakanyan D., Koliashvili T., Shmerko N. CLINICAL ASPECTS AND BIOCHEMICAL MARKERS OF BONE FORMATION AFTER LIVER TRANSPLANTATION. Russian Journal of Transplantology and Artificial Organs. 2012;14(1):19-26. (In Russ.) https://doi.org/10.15825/1995-1191-2012-1-19-26
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