Sleeve gastrectomy in a patient with morbid obesity following liver transplantation
https://doi.org/10.15825/1995-1191-2026-2-39-45
Abstract
Objective: to present a clinical case of laparoscopic sleeve gastrectomy (LSG) performed for morbid obesity following liver transplantation (LT). Materials and methods. A female patient (born 1968) with primary biliary cirrhosis underwent orthotopic LT in 2019. Three years later, she required anterior abdominal wall repair for a postoperative hernia. Subsequently, progressive weight gain and deterioration in quality of life were observed. Despite significant intra-abdominal adhesions, LSG was performed. The postoperative period was uneventful. Results. The patient demonstrated significant weight loss, improved quality of life, and preserved graft function. Conclusion. LSG is an effective treatment for morbid obesity and its associated complications following LT.
About the Authors
S. E. Grigoriev
Irkutsk Regional Clinical Hospital; Irkutsk State Medical University
Russian Federation
Russian Federation
Sergey E. Grigoriev.
100, Mikrorayon Yubileynyy, Irkutsk, 664049
Phone: (902) 176-71-06
M. O. Movsisyan
Irkutsk Regional Clinical Hospital; Irkutsk State Medical University
Russian Federation
Russian Federation
Irkutsk
A. V. Novozhilov
Irkutsk Regional Clinical Hospital; Irkutsk State Medical University
Russian Federation
Russian Federation
Irkutsk
A. M. Manvelyan
Irkutsk Regional Clinical Hospital
Russian Federation
Russian Federation
Irkutsk
References
1. García Ruiz de Gordejuela A, Ibarzabal A, Osorio J. Bariatric surgery and solid-organ transplantation. Transplant Proc. 2022; 54 (1): 87–90. https://doi.org/10.1016/j.transproceed.2021.11.008.
2. Diwan TS, Lee TC, Nagai S, Benedetti E, Posselt A, Bumgardner G et al. Obesity, transplantation, and bariatric surgery: An evolving solution for a growing epidemic. Am J Transplant. 2020; 20 (8): 2143–2155. https://doi.org/10.1111/ajt.15784.
3. Diwan TS, Rice TC, Heimbach JK, Schauer DP. Liver transplantation and bariatric surgery: timing and outcomes. Liver Transpl. 2018; 24 (9): 1280–1287. https://doi.org/10.1002/lt.25303.
4. Suraweera D, Dutson E, Saab S. Liver transplantation and bariatric surgery: best approach. Clin Liver Dis. 2017; 21 (02): 215–230. https://doi.org/10.1016/j.cld.2016.12.001.
5. Tejedor‑Tejada J, Garcia‑Pajares F, Safadi R, Mauriz-Barreiro V, Molina E et al. The impact of obesity on postoperative complications and short-term survival after liver transplantation. Eur J Gastroenterol Hepatol. 2023; 35 (7): 782–789. https://doi.org/10.1097/MEG.0000000000002574.
6. Dobrindt EM, Allex L, Saipbaev A, Öllinger R, Schöning W, Pratschke J et al. Association between obesity after liver transplantation and steatosis, inflammation, and fibrosis of the graft. Clin Transplant. 2020; 34 (12): e14093. https://doi.org/10.1111/ctr.14093.
7. Malinovskaya YuO, Kokina KYu, Moysyuk YaG, Sumtsova OV. The impact of late liver allograft dysfunction on physical activity of liver transplant recipients. Transplantologiya. The Russian Journal of Transplantation. 2021; 13 (4): 356–366. https://doi.org/10.23873/2074-0506-2021-13-4-356-366.
8. Lee Y, Tian C, Lovrics O, Soon MS, Doumouras AG, Anvari M et al. Bariatric surgery before, during, and after liver transplantation: a systematic review and meta-analysis. Surg Obes Relat Dis. 2020; 16 (9): 1336–1347. https://doi.org/10.1016/j.soard.2020.05.012.
9. Ahmed Z, Khan MA, Vazquez‑Montesino LM, Ahmed A. Bariatric surgery, obesity and liver transplantation. Transl Gastroenterol Hepatol. 2022; 7: 25. https://doi.org/10.21037/tgh-2020-14.
10. De Barros F, Cardoso Faleiro Uba PH. Liver transplantation and bariatric surgery: a new surgical reality: a systematic review of the best time for bariatric surgery. Updates Surg. 2021; 73 (5): 1615–1622. https://doi.org/10.1007/s13304-021-01106-3.
11. Safavi D, Creavin B, Gallagher TK, Kelly ME. The role of bariatric surgery in liver transplantation: timing and type. Langenbecks Arch Surg. 2022; 407 (8): 3249–3258. https://doi.org/10.1007/s00423-022-02606-5.
12. Tsamalaidze L, Stauffer JA, Arasi LC, Villacreses DE, Franco JSS, Bowers S et al. Laparoscopic sleeve gastrectomy for morbid obesity in patients after orthotopic liver transplant: A matched case-control study. Obes Surg. 2018; 28 (2): 444–450. https://doi.org/10.1007/s11695-017-2847-7.
13. Shenoy A, Bloom PP. Weight to go! – Glucagon-like peptide 1 receptor agonists in liver transplant recipients. Liver Transpl. 2024; 30 (2): 124–126. https://doi.org/10.1097/LVT.0000000000000291.
14. Melson E, Miras AD, Papamargaritis D. Future therapies for obesity. Clin Med (Lond). 2023; 23 (4): 337–346. https://doi.org/10.7861/clinmed.2023-0144.
15. Sugawara Y, Hibi T. Recent trends and new developments in liver transplantation. Biosci Trends. 2024; 18 (3): 206–211. https://doi.org/10.5582/bst.2024.01176.
Review
For citations:
Grigoriev S.E., Movsisyan M.O., Novozhilov A.V., Manvelyan A.M. Sleeve gastrectomy in a patient with morbid obesity following liver transplantation. Russian Journal of Transplantology and Artificial Organs. 2026;28(2):39-45. (In Russ.) https://doi.org/10.15825/1995-1191-2026-2-39-45
Views:
40
JATS XML
Email this article 