Heart transplantation for primary cardiac sarcoma
https://doi.org/10.15825/1995-1191-2022-3-74-79
Abstract
Primary cardiac sarcoma is a rapidly progressive, aggressive cardiac tumor that is very rare in the general population. Conservative treatment for this tumor is not very effective. The only effective treatment is radical surgical removal of the malignancy. However, if sarcoma removal cannot be performed, heart transplantation (HT) becomes the only treatment option. The median survival of heart recipients with preoperative cardiac sarcoma is 8.5 months. Globally, such operations are performed in a small number of cases. This paper presents the first experience of HT for a patient with primary cardiac sarcoma in the Russian Federation.
About the Authors
A. Yu. GoncharovaRussian Federation
Anna Goncharova
Address: 1, Shchukinskaya str., Moscow, 123182
Phone: (903) 110-84-95
N. N. Koloskova
Russian Federation
Moscow
V. N. Poptsov
Russian Federation
Moscow
V. M. Zakharevich
Russian Federation
Moscow
N. P. Mojeiko
Russian Federation
Moscow
А. R. Zakiryanov
Russian Federation
Moscow
N. N. Sayfullina
Russian Federation
Moscow
K. S. Kiryakov
Russian Federation
Moscow
S. V. Gautier
Russian Federation
Moscow
References
1. Reynen K. Frequency of primary tumors of the heart. American Journal of Cardiology. 1996; 77 (1): 107.
2. Siontis BL, Zhao L, Leja M et al. Primary Cardiac Sarcoma: A Rare, Aggressive Malignancy with a High Propensity for Brain Metastases. Sarcoma. 2019 Mar 10; 2019: 1960593.
3. Hamidi M, Moody JS, Weigel TL et al. Primary cardiac sarcoma. Ann Thorac Surg. 2010; 90: 176–181.
4. Gowdamarajan A, Michler RE. Therapy for primary cardiac tumors: Is there a role for heart transplantation? Curr Opin Cardiol. 2000; 15: 121–126.
5. Li H, Yang S, Chen H et al. Survival after heart transplantation for non-metastatic primary cardiac sarcoma. J Cardiothorac Surg. 2016; 11: 145.
6. Coelho P, Banazol N, Soares RJM et al. Long-term survival with heart transplantation for fibrosarcoma of the heart. Ann Thorac Surg. 2010; 90: 635–636.
7. Jimenez Mazuecos JM, Fuentes Manso R, Segovia Cubero J et al. Is heart transplantation for primary cardiac sarcoma a useful therapeutic option? Rev Esp Cardiol. 2003; 56: 408–411.
8. Noiclerc M, Chavanon O, Borrel E et al. Primary cardiac sarcoma treated by orthoptic cardiac transplantation. Apropos of a case. Arch Mal Coer Vaiss. 1997; 11: 1539–1543.
9. Yokoyama I, Carr B, Saitsu H et al. Accelerated growth rates of recurrent hepatocellular carcinoma after liver transplantation. Cancer. 1991; 68: 2095–2100.
10. Horn M, Phebus C, Blatt J. Cancer chemotherapy after solid organ transplantation. Cancer. 1990; 66: 1468– 1471.
11. Siebenmann R, Jenni R, Makek M et al. Primary synovial sarcoma of the heart treated by heart-transplantation. J Thorac Cardiovasc Surg. 1990; 99: 567–568.
12. Moreau LC, Turcotte R, Ferguson P. et al. Myxoidround cell liposarcoma (MRCLS) revisited: An analysis of 418 primarily managed cases. Ann Surg Oncol. 2012; 19: 1081–1088.
Review
For citations:
Goncharova A.Yu., Koloskova N.N., Poptsov V.N., Zakharevich V.M., Mojeiko N.P., Zakiryanov А.R., Sayfullina N.N., Kiryakov K.S., Gautier S.V. Heart transplantation for primary cardiac sarcoma. Russian Journal of Transplantology and Artificial Organs. 2022;24(3):74-79. https://doi.org/10.15825/1995-1191-2022-3-74-79