Mathematical evaluation of hemolysis in a channel centrifugal blood pump
https://doi.org/10.15825/1995-1191-2020-3-79-85
Abstract
The objective of this work is to conduct research on a mathematical model to assess hemolytic characteristics in a channel centrifugal blood pump developed by us with 2000–3400 rpm impeller speed range and 100–250 mmHg pressure drop in different parts of the pump flow path. Hemolysis index was measured at 1 to 10 L/min flow rate. The result was an estimate of the average magnitude of the shear stress (SS), taking into account the distribution in the pump, which ranged from 40 to 60 Pa. The most critical areas of the pump in terms of blood injury were evaluated. The maximum SSs were determined: 456 Pa in the impeller wheel zone and 533.3 Pa in the adjacent area of the body, with an exposure time of 0.0115 s and 0.0821 s respectively. In these zones, maximum hemolysis index values were 0.0420 and 0.0744 respectively. Based on the data obtained, these zones were optimized in terms of minimizing hemolysis.
About the Authors
A. P. Kuleshov
Shumakov National Medical Research Center of Transplantology and Artificial Organs
Russian Federation
Russian Federation
Arkady Kuleshov.
Address: 1, Shchukinskaya str., Moscow, Russian Federation.
Phone: (915) 292-47-98.
G. P. Itkin
Shumakov National Medical Research Center of Transplantology and Artificial Organs; Moscow Institute of Physics and Technology
Russian Federation
Russian Federation
Moscow
A. S. Buchnev
Shumakov National Medical Research Center of Transplantology and Artificial Organs
Russian Federation
Russian Federation
Moscow
A. A. Drobyshev
Shumakov National Medical Research Center of Transplantology and Artificial Organs
Russian Federation
Russian Federation
Moscow
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Review
For citations:
Kuleshov A.P., Itkin G.P., Buchnev A.S., Drobyshev A.A. Mathematical evaluation of hemolysis in a channel centrifugal blood pump. Russian Journal of Transplantology and Artificial Organs. 2020;22(3):79-85. https://doi.org/10.15825/1995-1191-2020-3-79-85
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