Heart transplantation from cardiac arrest-resuscitated donors
https://doi.org/10.15825/1995-1191-2019-2-23-30
Abstract
Heart transplantation from сardюpulmonary resuscitated (CPR) donors is one of the way to increase the availability of heart transplantation (HT). The study included 28 recipients: 25 (89,3%) men and 3 (10,7%) women at the age 20-68 (46,2 ± 13,7) who underwent HT from CPR donors in the V.I. Shumakov National Medical Research Center of Transplantology and Artificial Organs in the period from 01.01.2011 to 31.12.2017, that was 4.0% of the total number of HT (n = 698). CPR donor group and control group had no significantly differences in early cardiac transplant dysfunction and 1-, 3- and 5-year survival.
About the Authors
V. N. PoptsovRussian Federation
Poptsov Vitaliy Nikolaevich
1, Shchukinskaya str., Moscow, Tel. (963) 644-96-39
E. A. Spirina
Russian Federation
Moscow
V. V. Pchelnikov
Russian Federation
Moscow
V. M. Khatutsky
Russian Federation
Moscow
E. Z. Aliev
Russian Federation
Moscow
V. Yu. Voronkov
Russian Federation
Moscow
L. R. Nazipova
Russian Federation
Moscow
A. S. Yepremyan
Russian Federation
Moscow
E. N. Zolotova
Russian Federation
Moscow
A. I. Skokova
Russian Federation
Moscow
P. M. Aghasyan
Russian Federation
Moscow
References
1. Mehra MR. Heart transplantation at 50. Lancet. 2017; 390 (10111): e43-e45.
2. Laks H, Marelli D, Fonarow GC et al. Use of two recipient lists for adults requiring heart transplantation. J Thorac Cardiovasc Surg. 2003; 125: 49-59.
3. Shudo Y, Cohen JE, Lingala B et al. Impact of «increa-sed-risk» donor heart on transplant outcomes : a propensity-matched analysis. J Thorac Cardiovasc Surg. 2019; 157: 603-610.
4. Bernhardt AM, Reichenspurner H. High-risk donors: extending our criteria in time of organ shortage. Curr opin organ Transplant. 2014; 19: 494-499.
5. Tsao C, Chen RJ, Chou NK et al. The influence of donor characteristics on survival after heart transplantation. TransplantProc. 2008; 40: 2636-2637.
6. Delaunay L, Denis V, Darmon PL et al. Initial cardiac arrest is a risk factor for failure of organ procurement in brain-dead patients. Transplant Proc. 1996; 28: 289.
7. Sandroni C, D’Arrigo S, Callaway CW et al. The rate of brain death and organ donation in patients resuscitated from cardiac arrest: a systemic review and meta-analysis. Intensive care Med. 2016; 42: 1661-1671.
8. West S, Soar J, Callaway CW. The viability of transplanting organs from donors who underwent cardiopulmonary resuscitation: a systemic review. Resuscitation. 2016; 108: 27-33.
9. Cheng A, Schumer EM, Trivedi JR et al. Does donor cardiopulmonary resuscitation time affect heart transplantation outcomes and survival? Ann Thorac Surg. 2016; 102: 751-758.
10. Quader M, Wolfe L, Katlaps G, Kasirajan V. Donor Heart Utilization following cardiopulmonary arrest and resuscitation: influence of donor characteristics and wait times in transplant regions. Journal Transplantation. 2014; 519401. doi: 10.1155/2014/519.
11. Koponen T, Karttunen J, Musialowicz T et al. Vasoactive-inotropic score and the prediction of morbidity and mortality after cardiac surgery. Br JAnaesth. 2019; 122: 428-436.
12. Khush KK, Menza R, Nguyen J et al. Donor predictor of allograft use and recipient outcomes after heart transplantation. Circulation Haert failure. 2013; 6: 300-309.
13. Quader ML, Wolfe LG, Kasirajan V. Heart transplantation outcomes from cardiac arrest-resuscitaion donors. J Heart Lung transplant. 2013; 32: 1090-1095.
14. Samsky MD, Patel CB, Owen A et al. Ten-year experience with extended criteria cardiac transplantation. Circulation Heart Failure. 2013; 1230-1238.
15. Beuth J, Falter F, Pinto Riberto RV et al. New strategies to expand and optimize heart donor pool: ex vivo heart perfusion and donation after circulatory death: a review of current research and future trends. Anesth An-alg. 2019; 128: 406-413.
16. Page A, Messer S, Large SR. Heart transplantation from donation after circulatory determined death. Ann Cardio-thorac Surg. 2018; 7: 75-81.
17. White CW, Messer SJ, Large SR et al. Transplantaion of hearts donated after circulatory death. Front Cardiovasc Med. 2018 feb 13; 5: 8. Doi10.3389/fcvm.2018.00008.eCollection2018.Review.
18. Ali AA, Lim E, Thanikachalam Met al. Cardiac arrest in the organ donor does not negatively influence recipient survival after heart transplantation. Eur J Cardiothorac Surg. 2007; 31: 929-933.
19. de Begona JA, Gundry SR, Razzouk AJ et al. Transplantation of hearts after arrest and resuscitation. Early and long-time results. J Thorac Cardiovasc Surg. 1993; 106 (6): 1196-1201.
20. Kuhn MA, Chinnock RE. The acceptance of prolonged CPR donor in pediatric heart transplant recipients: are we ready to push the envelope? Pediatr Transplant. 2012: Nov 23; 16 (7): 678-679.
Review
For citations:
Poptsov V.N., Spirina E.A., Pchelnikov V.V., Khatutsky V.M., Aliev E.Z., Voronkov V.Yu., Nazipova L.R., Yepremyan A.S., Zolotova E.N., Skokova A.I., Aghasyan P.M. Heart transplantation from cardiac arrest-resuscitated donors. Russian Journal of Transplantology and Artificial Organs. 2019;21(2):23-30. (In Russ.) https://doi.org/10.15825/1995-1191-2019-2-23-30