vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2018-1-110-113vtio-861Research ArticleКлинические наблюденияClinical CasesКЛИНИЧЕСКИЙ СЛУЧАЙ ТРАНСПЛАНТАЦИИ СЕРДЦА С ПРЕДЕЛЬНО ДЛИТЕЛЬНОЙ ХОЛОДОВОЙ ИШЕМИЕЙ ДОНОРСКОГО ОРГАНАHEART TRANSPLANTATION WITH EXTREMELY EXTENDED COLD ISCHEMIA TIME OF THE DONOR HEARTАльсовС. А.AlsovS. A.ФомичевА. Ф.FomichevA. V.

Фомичев Алексей Вячеславович

630055, Новосибирск, ул. Речкуновская, 15

Fomichev Alexsey Vyacheslavovich

15, Rechkunovskaya st., Novosibirsk, 630055

a_fomichev@list.ruДоронинД. В.DoroninD. V.ШмыревВ. А.ShmyrevV. A.ОсиповД. Е.OsipovD. E.ЧернявскийА. М.ChernyavskiyA. M.ФГБУ «Национальный медицинский исследовательский центр имени академика Е.Н. Мешалкина», Министерства здравоохранения Российской ФедерацииРоссияMeshalkin National Medical Research Center, Ministry of Health of Russian FederationRussian Federation201824042018201110113Copyright © Альсов С.А., Фомичев А.Ф., Доронин Д.В., Шмырев В.А., Осипов Д.Е., Чернявский А.М., 20182018Альсов С.А., Фомичев А.Ф., Доронин Д.В., Шмырев В.А., Осипов Д.Е., Чернявский А.М.Alsov S.A., Fomichev A.V., Doronin D.V., Shmyrev V.A., Osipov D.E., Chernyavskiy A.M.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/861

Трансплантация сердца является золотым стандартом лечения терминальной сердечной недостаточности. Основным методом, используемым для консервации донорского сердца, является холодовая перфузия. Рекомендуемое максимальное время холодовой ишемии донорского сердца составляет 240 минут. Превышение этого безопасного порога увеличивает риск развития послеоперационной дисфункции аллографта и смерти. Однако существуют сообщения, согласно которым возможно продлить время ишемии донорского сердца без значительного риска развития осложнений. В статье представлен опыт успешной трансплантации донорского сердца, время холодовой ишемии которого составило 440 минут.

Heart transplantation is the gold standard for the treatment of terminal heart failure. The main method of the donor heart preservation is cold perfusion. The recommended maximum time for cold ischemia of the donor heart is 240 minutes. Exceeding this safe limit increases the risk of postoperative allograft dysfunction and death. However, there are reports positing a possibility to prolong the time of ischemia of the donor heart without a signifi cant risk of complications. The article presents the experience of successful transplantation of the donor heart with the cold ischemia time was 440 minutes.

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The authors declare that there are no conflicts of interest present.