References

vtio

Вестник трансплантологии и искусственных органов

Russian Journal of Transplantology and Artificial Organs

1995-1191

Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation

10.15825/1995-1191-2017-1-111-121

vtio-740

Research Article

Обзор литературы

Literature Reviews

Трансплантация почки и костная болезнь: факторы риска развития, диагностика

Kidney transplantation and bone disease: risk factors of development and diagnostics

Ветчинникова

О. Н.

Vetchinnikova

O. N.

Адрес: 129110, Москва, ул. Щепкина, д. 61/2, корп. 6. Тел. (916) 532-49-00

Address: 61/2, bl. 6, Shchepkina st., Moscow, 129110, Russian Federation. Tel. (916) 532-49-00

olg-vetchinnikova@yandex.ru

ГБУЗ МО «Московский областной научно-исследовательский клинический институт имени М.Ф. Владимирского»РоссияM.F. Vladimirsky Moscow Regional Clinical and Research InstituteRussian Federation

2017

14042017

191111121

2017

Ветчинникова О.Н.

Vetchinnikova O.N.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://journal.transpl.ru/vtio/article/view/740

Заболевание костей является серьезной и часто встречающейся патологией у пациентов, перенесших трансплантацию почки. Рассмотрены разнообразные связанные с трансплантацией почки причины возникновения костных нарушений в раннем и отдаленном послеоперационном периоде: дисбаланс гормонов – фактора роста фибробластов 23, паратиреоидного гормона, витамина D, – иммуносупрессивная терапия, нарушение минерального обмена. Описан наиболее распространенный клинический вариант течения посттрансплантационной костной болезни – вторичный остеопороз, факторы риска его развития и осложнения. Анализируется диагностический алгоритм для выявления, динамического наблюдения и оценки эффективности проводимого лечения костных нарушений.

Bone disease is a serious and common condition in patients after kidney transplantation. The review analyzed the causes of bone disorders in the early and late postoperative period that are associated with renal transplantation: fibroblast growth factor 23, parathyroid hormone, vitamin D, immunosuppressive therapy and imbalance of mineral metabolism. It shows the most common clinical variant of the post-transplant bone disease – secondary osteoporosis, risk factors of its development and complications. It presents the diagnostic algorithm for dynamic monitoring and evaluating the effectiveness of the treatment of bone disorders

трансплантация почкипосттрансплантационная костная болезнь

kidney transplantationpost-transplant bone disease

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The authors declare that there are no conflicts of interest present.