vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2016-4-157-169vtio-710Research ArticleОбзор литературыLiterature ReviewsПОВТОРНАЯ ТРАНСПЛАНТАЦИЯ ПОЧКИREPEAT KIDNEY TRANSPLANTATIONСушковА. И.SushkovA. I.

Адрес: 123182, Москва, ул. Щукинская, д. 1. Тел. (916) 177-89-24

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sushkov.transpl@gmail.comФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава РоссииРоссияV.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian FederationRussian Federation201628012017184157169Copyright © Сушков А.И., 20172017Сушков А.И.Sushkov A.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/710

В настоящее время для большинства пациентов с терминальной почечной недостаточностью пересадка почки является наилучшим методом заместительной почечной терапии (ЗПТ), который значительно увеличивает продолжительность и качество жизни. Прогресс в области органного донорства, хирургической техники, трансплантационной иммунологии и иммуносупрессии существенно улучшил непосредственные результаты трансплантаций. При этом отдаленная выживаемость трансплантатов в течение последних двух десятилетий практически не изменилась. Несоответствие между показателями отдаленной выживаемости реципиентов и трансплантатов привело к увеличению количества пациентов, утративших функцию пересаженной почки. Для большинства из них повторная трансплантация представляется оптимальным вариантом продолжения ЗПТ, хотя и сопряжена c большей частотой осложнений. При этом рекомендации по проведению ретрансплантации почки, основанные на принципах доказательной медицины, до сих пор отсутствуют. Настоящий обзор основан на материале 100 научных публикаций, посвященных различным аспектам планирования и выполнения ретрансплантации почки.

Nowadays, kidney transplantation is the best approach of renal replacement therapy for the majority of patients with end-stage renal disease that significantly improves the quality and length of life. Advances in the field of organ donation, immunosuppression, transplant surgery and immunology have improved short-term graft and patient survival. But the long-term graft survival remains static over last two decades. The disparity between low graft and high patient long-term survival led to increasing number of transplant recipients with failed grafts. Repeat renal transplant is presumed to be a good option for many patients losing their grafts, but it is associated with higher complication rates. Unfortunately, there are no evidence-based recommendations or guidelines for renal retransplantation procedure. This review is based on 100 scientifi c publications related to various aspects of the kidney retransplantation and provides the recent data on this matter.

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The authors declare that there are no conflicts of interest present.