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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vtio</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник трансплантологии и искусственных органов</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Transplantology and Artificial Organs</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-1191</issn><publisher><publisher-name>Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15825/1995-1191-2014-1-76-84</article-id><article-id custom-type="elpub" pub-id-type="custom">vtio-68</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзор литературы</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Literature Reviews</subject></subj-group></article-categories><title-group><article-title>НЕКОТОРЫЕ МЕХАНИЗМЫ ДЕЙСТВИЯ ЭКСТРАКОРПОРАЛЬНОЙ ФОТОХИМИОТЕРАПИИ ПРИ ТРАНСПЛАНТАЦИИ СОЛИДНЫХ ОРГАНОВ</article-title><trans-title-group xml:lang="en"><trans-title>SOME OF THE MECHANISMS OF EXTRACORPOREAL PHOTOCHEMOTHERAPY IN SOLID ORGAN TRANSPLANTATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ватазин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vatazin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p> </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зулькарнаев</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Zul'karnaev</surname><given-names>A. B.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кильдюшевский</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kil'djushevskij</surname><given-names>A. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федулкина</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedulkina</surname><given-names>V. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крстич</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Krstic</surname><given-names>M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>УЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского», Москва, Российская Федерация</institution></aff><aff xml:lang="en"><institution>Postgraduate Medical M.F. Vladimirsky Moscow Regional Clinical and Research Institute, Moscow, Russian Federation</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского», Москва, Российская Федерация</institution></aff><aff xml:lang="en"><institution>Postgraduate Medical M.F. Vladimirsky Moscow Regional Clinical and Research Institute, Moscow, Russian Federation</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>14</day><month>05</month><year>2014</year></pub-date><volume>16</volume><issue>1</issue><issue-title>ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XVI No 1–2014</issue-title><fpage>76</fpage><lpage>84</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ватазин А.В., Зулькарнаев А.Б., Кильдюшевский А.В., Федулкина В.А., Крстич М., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Ватазин А.В., Зулькарнаев А.Б., Кильдюшевский А.В., Федулкина В.А., Крстич М.</copyright-holder><copyright-holder xml:lang="en">Vatazin A.V., Zul'karnaev A.B., Kil'djushevskij A.V., Fedulkina V.A., Krstic M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.transpl.ru/vtio/article/view/68">https://journal.transpl.ru/vtio/article/view/68</self-uri><abstract><p>Снижение риска развития отторжения почечного трансплантата – перспективное направление современ- ной медицинской науки. Одним из перспективных методов снижения активности иммунологического конфликта между реципиентом и донорским органом и достижения частичной иммунологической толе- рантности является фотохимиотерапия. Этот метод широко применяется за рубежом при трансплантации сердца и легких. Отечественный опыт применения этого метода у реципиентов почечного транспланта- та крайне мал. В настоящем обзоре литературы представлено современное представление о механизме действия этого метода. </p></abstract><trans-abstract xml:lang="en"><p>Reducing the risk of kidney transplant rejection is a perspective trend in modern medical science. One of the promising methods for reducing the activity of immune conflict between the recipient and the donor organ and the achievement of partial immunological tolerance is photochemotherapy. This method is widely used in over- seas heart and lung Transplantation. Domestic experience of applying this method in renal transplant recipients is extremely small. In this review of literature a modern representation of the scientists on the mechanism of action of this method is presented. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>фотохимиотерапия</kwd><kwd>трансплантация почки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>photochemotherapy</kwd><kwd>kidney transplantation.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">СПИСОК ЛИТЕРАТУРЫ / REFERENCES</mixed-citation><mixed-citation xml:lang="en">СПИСОК ЛИТЕРАТУРЫ / REFERENCES</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">MCKenna K.E., Whittaker S., Rhodes L.E., Tailor P., Lloyd J., Ibbson S., Russel-Jones R. Evidence – baced practice of photopheresis 1987 – 2001: a report of a workshop of the British Photodermatology group and the U.K. skin lymphoma group. Br. J. Dermatol. 2006; 154: 7–20.</mixed-citation><mixed-citation xml:lang="en">MCKenna K.E., Whittaker S., Rhodes L.E., Tailor P., Lloyd J., Ibbson S., Russel-Jones R. Evidence – baced practice of photopheresis 1987 – 2001: a report of a workshop of the British Photodermatology group and the U.K. skin lymphoma group. Br. J. Dermatol. 2006; 154: 7–20.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Pierelli L., Perseghin P., Marchetti M., Messina C., Pe- rotti C., Mazzoni A., Bacigalupo A., Locatelli F., Carli- er P., Bosi A. Società Italiana di Emaferesi and Manipo- lazione Cellulare (SIdEM) and Gruppo Italiano Trapianto Midollo Osseo (GITMO). Extracorporeal photopheresis for the treatment of acute and chronic graft-versus-host disease in adults and children: best practice recommen- dations from an Italian Society of Hemapheresis and Cell Manipulation (SIdEM) and Italian Group for Bone Mar- row Transplantation (GITMO) consensus process. Trans- fusion. 2013; 53 (10): 2340–2352.</mixed-citation><mixed-citation xml:lang="en">Pierelli L., Perseghin P., Marchetti M., Messina C., Pe- rotti C., Mazzoni A., Bacigalupo A., Locatelli F., Carli- er P., Bosi A. Società Italiana di Emaferesi and Manipo- lazione Cellulare (SIdEM) and Gruppo Italiano Trapianto Midollo Osseo (GITMO). Extracorporeal photopheresis for the treatment of acute and chronic graft-versus-host disease in adults and children: best practice recommen- dations from an Italian Society of Hemapheresis and Cell Manipulation (SIdEM) and Italian Group for Bone Mar- row Transplantation (GITMO) consensus process. Trans- fusion. 2013; 53 (10): 2340–2352.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Jaksch P., Scheed A., Keplinger M., Ernst M.B., Dani T., Just U., Nahavandi H., Klepetko W., Knobler R. A pro-</mixed-citation><mixed-citation xml:lang="en">Jaksch P., Scheed A., Keplinger M., Ernst M.B., Dani T., Just U., Nahavandi H., Klepetko W., Knobler R. A pro-</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">spective interventional study on the use of extracorpo- realphotopheresis in patients with bronchiolitis obliter- ans syndrome after lungtransplantation. J. Heart Lung Transplant. 2012; 31 (9): 950–957.</mixed-citation><mixed-citation xml:lang="en">spective interventional study on the use of extracorpo- realphotopheresis in patients with bronchiolitis obliter- ans syndrome after lungtransplantation. J. Heart Lung Transplant. 2012; 31 (9): 950–957.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Lucid C.E., Savani B.N., Engelhardt B.G., Shah P., Clif- ton C., Greenhut S.L., Vaughan L.A., Kassim A., Schuen- ing F., Jagasia M. Extracorporeal photopheresis in pa- tients with refractory bronchiolitis obliterans developing after allo-SCT. Bone Marrow Transplant. 2011; 46 (3): 426–429.</mixed-citation><mixed-citation xml:lang="en">Lucid C.E., Savani B.N., Engelhardt B.G., Shah P., Clif- ton C., Greenhut S.L., Vaughan L.A., Kassim A., Schuen- ing F., Jagasia M. Extracorporeal photopheresis in pa- tients with refractory bronchiolitis obliterans developing after allo-SCT. Bone Marrow Transplant. 2011; 46 (3): 426–429.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Dall'Amico R., Montini G., Murer L., Andreetta B., Zac- chello G., Gambino A., Feltrin G., Caforio A., Tursi V., Livi U. Extracorporeal photochemotherapy after cardiac transplantation: a new therapeutic approach to allograft rejection. Int. J. Artif. Organs. 2000; 23 (1): 49–54.</mixed-citation><mixed-citation xml:lang="en">Dall'Amico R., Montini G., Murer L., Andreetta B., Zac- chello G., Gambino A., Feltrin G., Caforio A., Tursi V., Livi U. Extracorporeal photochemotherapy after cardiac transplantation: a new therapeutic approach to allograft rejection. Int. J. Artif. Organs. 2000; 23 (1): 49–54.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Marques M.B., Schwartz J. Update on extracorporeal photopheresis in heart and lung transplantation. J. Clin. Apher. 2011; 26 (3): 146–151.</mixed-citation><mixed-citation xml:lang="en">Marques M.B., Schwartz J. Update on extracorporeal photopheresis in heart and lung transplantation. J. Clin. Apher. 2011; 26 (3): 146–151.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Urbani L., Mazzoni A., Colombatto P., Biancofiore G., Bindi L., Tascini C., Menichetti F., Brunetto M., Sca- tena F., Filipponi F. Potential applications of extracor- poreal photopheresis in liver transplantation. Transplant. Proc. 2008; 40 (4): 1175–1178.</mixed-citation><mixed-citation xml:lang="en">Urbani L., Mazzoni A., Colombatto P., Biancofiore G., Bindi L., Tascini C., Menichetti F., Brunetto M., Sca- tena F., Filipponi F. Potential applications of extracor- poreal photopheresis in liver transplantation. Transplant. Proc. 2008; 40 (4): 1175–1178.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Urbani L., Mazzoni A., Bianco I., Grazzini T., De Simo- ne P., Catalano G., Montin U., Petruccelli S., Morelli L., Campani D., Pollina L., Biancofiore G., Bindi L., Tas- cini C., Menichetti F., Scatena F., Filipponi F. The role of immunomodulation in ABO-incompatible adult liver transplant recipients. J. Clin. Apher. 2008; 23 (2): 55–62.</mixed-citation><mixed-citation xml:lang="en">Urbani L., Mazzoni A., Bianco I., Grazzini T., De Simo- ne P., Catalano G., Montin U., Petruccelli S., Morelli L., Campani D., Pollina L., Biancofiore G., Bindi L., Tas- cini C., Menichetti F., Scatena F., Filipponi F. The role of immunomodulation in ABO-incompatible adult liver transplant recipients. J. Clin. Apher. 2008; 23 (2): 55–62.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Kusztal M., Kościelska-Kasprzak K., Gdowska W., Zabińska M., Myszka M., Kłak R., Krajewska M., Boratyńska M., Szyber P., Chudoba P., Patrzałek D., Klinger M. Extracorporeal photopheresis as an antirejec- tion prophylaxis in kidney transplant recipients: prelimi- nary results. Transplant. Proc. 2011; 43 (8): 2938–2940.</mixed-citation><mixed-citation xml:lang="en">Kusztal M., Kościelska-Kasprzak K., Gdowska W., Zabińska M., Myszka M., Kłak R., Krajewska M., Boratyńska M., Szyber P., Chudoba P., Patrzałek D., Klinger M. Extracorporeal photopheresis as an antirejec- tion prophylaxis in kidney transplant recipients: prelimi- nary results. Transplant. Proc. 2011; 43 (8): 2938–2940.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Scarisbrick J. Extracorporeal photopheresis: what is it and when should it be used? Clin. Exp. Dermatol. 2009; 34 (7): 757–760.</mixed-citation><mixed-citation xml:lang="en">Scarisbrick J. Extracorporeal photopheresis: what is it and when should it be used? Clin. Exp. Dermatol. 2009; 34 (7): 757–760.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Genberg H., Kumlien G., Shanwell A., Tydén G. Refrac- tory acute renal allograft rejection successfully treated with photopheresis. Transplant. Proc. 2005; 37 (8): 3288–3289.</mixed-citation><mixed-citation xml:lang="en">Genberg H., Kumlien G., Shanwell A., Tydén G. Refrac- tory acute renal allograft rejection successfully treated with photopheresis. Transplant. Proc. 2005; 37 (8): 3288–3289.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Jardine M.J., Bhandari S., Wyburn K.R., Misra A.K., McKenzie P.R., Eris J.M. Photopheresis therapy for problematic renal allograft rejection. J. Clin. Apher. 2009; 24 (4): 161–169.</mixed-citation><mixed-citation xml:lang="en">Jardine M.J., Bhandari S., Wyburn K.R., Misra A.K., McKenzie P.R., Eris J.M. Photopheresis therapy for problematic renal allograft rejection. J. Clin. Apher. 2009; 24 (4): 161–169.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Lai Q., Pretagostini R., Gozzer M., Cinti P., Meo D., Vita F., Bafti M.S., Poli L., Novelli G., Rossi M., Gire- lli G., Berloco P.B. Multimodal treatment for acute an- tibody-mediated renal transplant rejection: successful rescue therapy with combined plasmapheresis, photo- pheresis and intravenous immunoglobulin. G. Ital. Ne- frol. 2012; 29 Suppl 54: S31–35.</mixed-citation><mixed-citation xml:lang="en">Lai Q., Pretagostini R., Gozzer M., Cinti P., Meo D., Vita F., Bafti M.S., Poli L., Novelli G., Rossi M., Gire- lli G., Berloco P.B. Multimodal treatment for acute an- tibody-mediated renal transplant rejection: successful rescue therapy with combined plasmapheresis, photo- pheresis and intravenous immunoglobulin. G. Ital. Ne- frol. 2012; 29 Suppl 54: S31–35.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Benden C., Speich R., Hofbauer G.F., Irani S., Eich- Wanger C., Russi E.W., Weder W., Boehler A. Extracor- poreal photopheresis after lung transplantation: a 10- year single-center experience. Transplantation. 2008; 86 (11): 1625–1627.</mixed-citation><mixed-citation xml:lang="en">Benden C., Speich R., Hofbauer G.F., Irani S., Eich- Wanger C., Russi E.W., Weder W., Boehler A. Extracor- poreal photopheresis after lung transplantation: a 10- year single-center experience. Transplantation. 2008; 86 (11): 1625–1627.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Morrell M.R., Despotis G.J., Lublin D.M., Patter- son G.A., Trulock E.P., Hachem R.R. The efficacy of photopheresis for bronchiolitis obliterans syndrome after lung transplantation. J. Heart Lung Transplant. 2010; 29 (4): 424–431.</mixed-citation><mixed-citation xml:lang="en">Morrell M.R., Despotis G.J., Lublin D.M., Patter- son G.A., Trulock E.P., Hachem R.R. The efficacy of photopheresis for bronchiolitis obliterans syndrome after lung transplantation. J. Heart Lung Transplant. 2010; 29 (4): 424–431.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Salerno C.T., Park S.J., Kreykes N.S., Kulick D.M., Sa- vik K., Hertz M.I., Bolman R.M. 3rd. Adjuvant treatment of refractory lung transplant rejection with extracorpo- real photopheresis. J. Thorac. Cardiovasc. Surg. 1999; 117 (6): 1063–1069.</mixed-citation><mixed-citation xml:lang="en">Salerno C.T., Park S.J., Kreykes N.S., Kulick D.M., Sa- vik K., Hertz M.I., Bolman R.M. 3rd. Adjuvant treatment of refractory lung transplant rejection with extracorpo- real photopheresis. J. Thorac. Cardiovasc. Surg. 1999; 117 (6): 1063–1069.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Villanueva J., Bhorade S.M., Robinson J.A., Husain A.N., Garrity E.R. Jr. Extracorporeal photopheresis for the treatment of lung allograft rejection. Ann. Transplant. 2000; 5 (3): 44–47.</mixed-citation><mixed-citation xml:lang="en">Villanueva J., Bhorade S.M., Robinson J.A., Husain A.N., Garrity E.R. Jr. Extracorporeal photopheresis for the treatment of lung allograft rejection. Ann. Transplant. 2000; 5 (3): 44–47.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Giunti G., Schürfeld K., Maccherini M., Tanganelli P., Rubegni P., Alfani D., D'Ascenzo G., Diciolla F., Bernaz- zali S., Fimiani M., Toscano M., Sani G. Photopheresis for recurrent acute rejection in cardiac transplantation. Transplant. Proc. 1999; 31 (1–2): 128–129.</mixed-citation><mixed-citation xml:lang="en">Giunti G., Schürfeld K., Maccherini M., Tanganelli P., Rubegni P., Alfani D., D'Ascenzo G., Diciolla F., Bernaz- zali S., Fimiani M., Toscano M., Sani G. Photopheresis for recurrent acute rejection in cardiac transplantation. Transplant. Proc. 1999; 31 (1–2): 128–129.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Maccherini M., Diciolla F., Laghi Pasini F., Lisi G., Tan- ganelli P., D'Ascenzo G., Mondillo S., Carone E., Oric- chio L., Baraldi C., Capecchi P.L., Lazzerini P.E., Tosca- no T., Barretta A., Giunti G., Schuerfeld K., Fimiani M., Papalia U. Photopheresis immunomodulation after heart transplantation. Transplant. Proc. 2001; 33 (1–2): 1591– 1594.</mixed-citation><mixed-citation xml:lang="en">Maccherini M., Diciolla F., Laghi Pasini F., Lisi G., Tan- ganelli P., D'Ascenzo G., Mondillo S., Carone E., Oric- chio L., Baraldi C., Capecchi P.L., Lazzerini P.E., Tosca- no T., Barretta A., Giunti G., Schuerfeld K., Fimiani M., Papalia U. Photopheresis immunomodulation after heart transplantation. Transplant. Proc. 2001; 33 (1–2): 1591– 1594.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Barr M.L., Meiser B.M., Eisen H.J., Roberts R.F., Livi U., Dall'Amico R., Dorent R., Rogers J.G., Radovancević B., Taylor D.O., Jeevanandam V., Marboe C.C. Photophere- sis for the prevention of rejection in cardiac transplan- tation. Photopheresis Transplantation Study Group. N. Engl. J. Med. 1998; 339 (24): 1744–51.</mixed-citation><mixed-citation xml:lang="en">Barr M.L., Meiser B.M., Eisen H.J., Roberts R.F., Livi U., Dall'Amico R., Dorent R., Rogers J.G., Radovancević B., Taylor D.O., Jeevanandam V., Marboe C.C. Photophere- sis for the prevention of rejection in cardiac transplan- tation. Photopheresis Transplantation Study Group. N. Engl. J. Med. 1998; 339 (24): 1744–51.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Kirklin J.K., Brown R.N., Huang S.T., Naftel D.C., Hub- bard S.M., Rayburn B.K., McGiffi n D.C., Bourge R.B., Benza R.L., Tallaj J.A., Pinderski L.J., Pamboukian S.V., George J.F., Marques M. Rejection with hemodynamic compromise: objective evidence for efficacy of photo- pheresis. J. Heart Lung Transplant. 2006; 25 (3): 283– 288.</mixed-citation><mixed-citation xml:lang="en">Kirklin J.K., Brown R.N., Huang S.T., Naftel D.C., Hub- bard S.M., Rayburn B.K., McGiffi n D.C., Bourge R.B., Benza R.L., Tallaj J.A., Pinderski L.J., Pamboukian S.V., George J.F., Marques M. Rejection with hemodynamic compromise: objective evidence for efficacy of photo- pheresis. J. Heart Lung Transplant. 2006; 25 (3): 283– 288.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Holtick U., Wang X.N., Marshall S.R., Scheid C., von Bergwelt-Baildon M., Dickinson A.M. In vitro PUVA treatment preferentially induces apoptosis in alloacti- vated T cells. Transplantation. 2012; 94 (5): e31–34.</mixed-citation><mixed-citation xml:lang="en">Holtick U., Wang X.N., Marshall S.R., Scheid C., von Bergwelt-Baildon M., Dickinson A.M. In vitro PUVA treatment preferentially induces apoptosis in alloacti- vated T cells. Transplantation. 2012; 94 (5): e31–34.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Hannani D., Gabert F., Laurin D., Sall M., Molens J.P., Hequet O., Chaperot L., Plumas J. Photochemotherapy induces the apoptosis of monocytes without impairing their function. Transplantation. 2010; 89 (5): 492–499.</mixed-citation><mixed-citation xml:lang="en">Hannani D., Gabert F., Laurin D., Sall M., Molens J.P., Hequet O., Chaperot L., Plumas J. Photochemotherapy induces the apoptosis of monocytes without impairing their function. Transplantation. 2010; 89 (5): 492–499.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Hannani D., Merlin E., Gabert F., Laurin D., De- méocq F., Chaperot L., Kanold J., Plumas J. Photoche- motherapy induces a faster apoptosis of alloreactive ac- tivated T cells than of nonalloreactive resting T cells in graft versus host disease. Transplantation. 2010; 90 (11): 1232–1238.</mixed-citation><mixed-citation xml:lang="en">Hannani D., Merlin E., Gabert F., Laurin D., De- méocq F., Chaperot L., Kanold J., Plumas J. Photoche- motherapy induces a faster apoptosis of alloreactive ac- tivated T cells than of nonalloreactive resting T cells in graft versus host disease. Transplantation. 2010; 90 (11): 1232–1238.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Baron E.D., Heeger P.S., Hricik D.E., Schulak J.A., Tary- Lehmann M., Stevens S.R. Immunomodulatory effect of extracorporeal photopheresis after successful treatment of resistant renal allograft rejection. Photodermatol. Photoimmunol. Photomed. 2001; 17 (2): 79–82.</mixed-citation><mixed-citation xml:lang="en">Baron E.D., Heeger P.S., Hricik D.E., Schulak J.A., Tary- Lehmann M., Stevens S.R. Immunomodulatory effect of extracorporeal photopheresis after successful treatment of resistant renal allograft rejection. Photodermatol. Photoimmunol. Photomed. 2001; 17 (2): 79–82.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Fimiani M., Di Renzo M., Rubegni P. Mechanism of ac- tion of extracorporeal photochemotherapy in chronic graft-versus-host disease. Br. J. Dermatol. 2004; 150 (6): 1055–1060.</mixed-citation><mixed-citation xml:lang="en">Fimiani M., Di Renzo M., Rubegni P. Mechanism of ac- tion of extracorporeal photochemotherapy in chronic graft-versus-host disease. Br. J. Dermatol. 2004; 150 (6): 1055–1060.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Setterblad N., Garban F., Weigl R., Assier E., Drillat P., Charron D., Dickinson A., Greinix H., Mooney N. Extra- corporeal photophoresis increases sensitivity of monocytes from patients with graft-versus-host disease to HLA-DR- mediated cell death. Transfusion. 2008; 48 (1): 169–177.</mixed-citation><mixed-citation xml:lang="en">Setterblad N., Garban F., Weigl R., Assier E., Drillat P., Charron D., Dickinson A., Greinix H., Mooney N. Extra- corporeal photophoresis increases sensitivity of monocytes from patients with graft-versus-host disease to HLA-DR- mediated cell death. Transfusion. 2008; 48 (1): 169–177.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Bains S.K., Mone A., Yun Tso J., Lucas D., Byrd J.C., Weiner G.J., Green J.M. Mitochondria control of cell death induced by anti-HLA-DR antibodies. Leukemia. 2003; 17 (7): 1357–1365.</mixed-citation><mixed-citation xml:lang="en">Bains S.K., Mone A., Yun Tso J., Lucas D., Byrd J.C., Weiner G.J., Green J.M. Mitochondria control of cell death induced by anti-HLA-DR antibodies. Leukemia. 2003; 17 (7): 1357–1365.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Bladon J., Taylor P. Extracorporeal photopheresis re- duces the number of mononuclear cells that produce pro- inflammatory cytokines, when tested ex-vivo. J. Clin. Apher. 2002; 17 (4): 177–182.</mixed-citation><mixed-citation xml:lang="en">Bladon J., Taylor P. Extracorporeal photopheresis re- duces the number of mononuclear cells that produce pro- inflammatory cytokines, when tested ex-vivo. J. Clin. Apher. 2002; 17 (4): 177–182.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Bladon J., Taylor P.C. Lymphocytes treated by extracor- poreal photopheresis can down-regulate cytokine pro- duction in untreated monocytes. Photodermatol. Photo- immunol. Photomed. 2005; 21 (6): 293–302.</mixed-citation><mixed-citation xml:lang="en">Bladon J., Taylor P.C. Lymphocytes treated by extracor- poreal photopheresis can down-regulate cytokine pro- duction in untreated monocytes. Photodermatol. Photo- immunol. Photomed. 2005; 21 (6): 293–302.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Ghafari A., Makhdoomi K., Ahmadpour P., Afshari A.T., Lak S.S., Fakhri L. Serum T-lymphocyte cytokines can- not predict early acute rejection in renal transplantation. Transplant. Proc. 2007; 39 (4): 958–961.</mixed-citation><mixed-citation xml:lang="en">Ghafari A., Makhdoomi K., Ahmadpour P., Afshari A.T., Lak S.S., Fakhri L. Serum T-lymphocyte cytokines can- not predict early acute rejection in renal transplantation. Transplant. Proc. 2007; 39 (4): 958–961.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Holtick U., Wang X.N., Marshall S.R., Scheid C., von Bergwelt-Baildon M., Dickinson A.M. Immature DC isolated after co-culture with PUVA-treated peripheral blood mononuclear cells downregulate graft-versus-host reactions in the human skin explant model. Curr. Stem Cell Res. Ther. 2013; 8 (4): 324–332.</mixed-citation><mixed-citation xml:lang="en">Holtick U., Wang X.N., Marshall S.R., Scheid C., von Bergwelt-Baildon M., Dickinson A.M. Immature DC isolated after co-culture with PUVA-treated peripheral blood mononuclear cells downregulate graft-versus-host reactions in the human skin explant model. Curr. Stem Cell Res. Ther. 2013; 8 (4): 324–332.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">del Rio M.L., Buhler L., Gibbons C., Tian J., Rodriguez- Barbosa J.I. PD-1/PD-L1, PD-1/PD-L2, and other co-in- hibitory signaling pathways in transplantation. Transpl. Int. 2008; 21 (11): 1015–1028.</mixed-citation><mixed-citation xml:lang="en">del Rio M.L., Buhler L., Gibbons C., Tian J., Rodriguez- Barbosa J.I. PD-1/PD-L1, PD-1/PD-L2, and other co-in- hibitory signaling pathways in transplantation. Transpl. Int. 2008; 21 (11): 1015–1028.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Wolnicka-Glubisz A., Fraczek J., Skrzeczynska-Monc- znik J., Friedlein G., Mikolajczyk T., Sarna T., Pryjma J. Effect of UVA and 8-methoxypsoralen, 4, 6, 4'-trimethy- langelicin or chlorpromazine on apoptosis of lympho- cytes and their recognition by monocytes. J. Physiol. Pharmacol. 2010; 61 (1): 107–114.</mixed-citation><mixed-citation xml:lang="en">Wolnicka-Glubisz A., Fraczek J., Skrzeczynska-Monc- znik J., Friedlein G., Mikolajczyk T., Sarna T., Pryjma J. Effect of UVA and 8-methoxypsoralen, 4, 6, 4'-trimethy- langelicin or chlorpromazine on apoptosis of lympho- cytes and their recognition by monocytes. J. Physiol. Pharmacol. 2010; 61 (1): 107–114.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Di Renzo M., Rubegni P., Pasqui A.L., Pompella G., De Aloe G., Sbano P., Cuccia A., Castagnini C., Auteri A., Laghi Pasini F., Fimiani M. Extracorporeal photophere- sis affects interleukin (IL)-10 and IL-12 production by monocytes in patients with chronic graft-versus-host di- sease. Br. J. Dermatol. 2005; 153 (1): 59–65.</mixed-citation><mixed-citation xml:lang="en">Di Renzo M., Rubegni P., Pasqui A.L., Pompella G., De Aloe G., Sbano P., Cuccia A., Castagnini C., Auteri A., Laghi Pasini F., Fimiani M. Extracorporeal photophere- sis affects interleukin (IL)-10 and IL-12 production by monocytes in patients with chronic graft-versus-host di- sease. Br. J. Dermatol. 2005; 153 (1): 59–65.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Peritt D. Potential mechanisms of photopheresis in he- matopoietic stem cell transplantation. Biol. Blood Mar- row Transplant. 2006; 12 (1 Suppl 2): 7–12.</mixed-citation><mixed-citation xml:lang="en">Peritt D. Potential mechanisms of photopheresis in he- matopoietic stem cell transplantation. Biol. Blood Mar- row Transplant. 2006; 12 (1 Suppl 2): 7–12.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Di Renzo M., Sbano P., De Aloe G., Pasqui A.L., Ru- begni P., Ghezzi A., Auteri A., Fimiani M. Extracorporeal photopheresis affects co-stimulatory molecule expres- sion and interleukin-10 production bydendritic cells in graft-versus-host disease patients. Clin. Exp. Immunol. 2008; 151 (3): 407–413.</mixed-citation><mixed-citation xml:lang="en">Di Renzo M., Sbano P., De Aloe G., Pasqui A.L., Ru- begni P., Ghezzi A., Auteri A., Fimiani M. Extracorporeal photopheresis affects co-stimulatory molecule expres- sion and interleukin-10 production bydendritic cells in graft-versus-host disease patients. Clin. Exp. Immunol. 2008; 151 (3): 407–413.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Dhodapkar M.V., Steinman R.M., Krasovsky J., Munz C., Bhardwaj N. Antigen-specific inhibition of effector T cell function in humans after injection of immature den- dritic cells. J. Exp. Med. 2001; 193 (2): 233–238.</mixed-citation><mixed-citation xml:lang="en">Dhodapkar M.V., Steinman R.M., Krasovsky J., Munz C., Bhardwaj N. Antigen-specific inhibition of effector T cell function in humans after injection of immature den- dritic cells. J. Exp. Med. 2001; 193 (2): 233–238.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Dhodapkar M.V., Steinman R.M. Antigen-bearing imma- ture dendritic cells induce peptide-specific CD8(+) regu- latory T cells in vivo in humans. Blood. 2002; 100 (1): 174–177.</mixed-citation><mixed-citation xml:lang="en">Dhodapkar M.V., Steinman R.M. Antigen-bearing imma- ture dendritic cells induce peptide-specific CD8(+) regu- latory T cells in vivo in humans. Blood. 2002; 100 (1): 174–177.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">￼40. Spisek R., Gasova Z., Bartunkova J. Maturation state of dendritic cells during the extracorporeal photopheresis and its relevance for the treatment of chronic graft-ver- sus-host disease. Transfusion. 2006; 46 (1): 55–65.</mixed-citation><mixed-citation xml:lang="en">￼40. Spisek R., Gasova Z., Bartunkova J. Maturation state of dendritic cells during the extracorporeal photopheresis and its relevance for the treatment of chronic graft-ver- sus-host disease. Transfusion. 2006; 46 (1): 55–65.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Failli A., Legitimo A., Mazzoni A., Urbani L., Scatena F., Mosca F., Consolini R. The combination of immunosup- pressive drugs with 8-methoxypsoralen and ultraviolet a light modulates the myeloid-derived dendritic cell function. Int. J. Immunopathol. Pharmacol. 2011; 24 (1): 89–99.</mixed-citation><mixed-citation xml:lang="en">Failli A., Legitimo A., Mazzoni A., Urbani L., Scatena F., Mosca F., Consolini R. The combination of immunosup- pressive drugs with 8-methoxypsoralen and ultraviolet a light modulates the myeloid-derived dendritic cell function. Int. J. Immunopathol. Pharmacol. 2011; 24 (1): 89–99.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Tan J.K., O'Neill H.C. Maturation requirements for den- dritic cells in T cell stimulation leading to tolerance ver- sus immunity. J. Leukoc. Biol. 2005; 78 (2): 319–324.</mixed-citation><mixed-citation xml:lang="en">Tan J.K., O'Neill H.C. Maturation requirements for den- dritic cells in T cell stimulation leading to tolerance ver- sus immunity. J. Leukoc. Biol. 2005; 78 (2): 319–324.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Usharauli D. Dendritic cells and the immunity/tolerance decision. Med. Hypotheses. 2005; 64 (1): 112–113.</mixed-citation><mixed-citation xml:lang="en">Usharauli D. Dendritic cells and the immunity/tolerance decision. Med. Hypotheses. 2005; 64 (1): 112–113.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Meloni F., Cascina A., Miserere S., Perotti C., Vitulo P., Fietta A.M. Peripheral CD4(+)CD25(+) TREG cell counts and the response to extracorporeal photopheresis in lung transplant recipients. Transplant. Proc. 2007; 39 (1): 213–217.</mixed-citation><mixed-citation xml:lang="en">Meloni F., Cascina A., Miserere S., Perotti C., Vitulo P., Fietta A.M. Peripheral CD4(+)CD25(+) TREG cell counts and the response to extracorporeal photopheresis in lung transplant recipients. Transplant. Proc. 2007; 39 (1): 213–217.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">George J.F., Gooden C.W., Guo L., Kirklin J.K. Role for CD4(+)CD25(+) T cells in inhibition of graft rejection by extracorporeal photopheresis. J. Heart Lung Trans- plant. 2008; 27 (6): 616–622.</mixed-citation><mixed-citation xml:lang="en">George J.F., Gooden C.W., Guo L., Kirklin J.K. Role for CD4(+)CD25(+) T cells in inhibition of graft rejection by extracorporeal photopheresis. J. Heart Lung Trans- plant. 2008; 27 (6): 616–622.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Rubegni P., Sbano P., Cevenini G., Perari M.G., Ma- rotta G., Risulo M., Carcagnì M.R., D' Ascenzo G., De</mixed-citation><mixed-citation xml:lang="en">Rubegni P., Sbano P., Cevenini G., Perari M.G., Ma- rotta G., Risulo M., Carcagnì M.R., D' Ascenzo G., De</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Aloe G., Fimiani M. CD4+CD25+ lymphocyte subsets in chronic graft versus host disease patients undergoing ex- tracorporeal photochemotherapy. Int. J. Immunopathol. Pharmacol. 2007; 20 (4): 801–807.</mixed-citation><mixed-citation xml:lang="en">Aloe G., Fimiani M. CD4+CD25+ lymphocyte subsets in chronic graft versus host disease patients undergoing ex- tracorporeal photochemotherapy. Int. J. Immunopathol. Pharmacol. 2007; 20 (4): 801–807.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Lamioni A., Carsetti R., Legato A., Landolfo A., Isac- chi G., Emma F., Bottazzo G.F., Dello Strologo L. In- duction of regulatory T cells after prophylactic treatment with photopheresis in renal transplant recipients. Trans- plantation. 2007; 83 (10): 1393–1396.</mixed-citation><mixed-citation xml:lang="en">Lamioni A., Carsetti R., Legato A., Landolfo A., Isac- chi G., Emma F., Bottazzo G.F., Dello Strologo L. In- duction of regulatory T cells after prophylactic treatment with photopheresis in renal transplant recipients. Trans- plantation. 2007; 83 (10): 1393–1396.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Dupont E., Craciun L. UV-induced immunosuppressive and anti-inflammatory actions: mechanisms and clinical applications. Immunotherapy. 2009; 1 (2): 205–210.</mixed-citation><mixed-citation xml:lang="en">Dupont E., Craciun L. UV-induced immunosuppressive and anti-inflammatory actions: mechanisms and clinical applications. Immunotherapy. 2009; 1 (2): 205–210.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Федулкина В.А., Ватазин А.В., Кильдюшевский А.В., Столяревич Е.С., Кантария Р.О., Зулькарнаев А.Б. Трансляционная клеточная иммунотерапия при ал- лотрансплантации трупной почки у урологических больных. Альманах клинической медицины. 2013; 28: 25–31.</mixed-citation><mixed-citation xml:lang="en">Федулкина В.А., Ватазин А.В., Кильдюшевский А.В., Столяревич Е.С., Кантария Р.О., Зулькарнаев А.Б. Трансляционная клеточная иммунотерапия при ал- лотрансплантации трупной почки у урологических больных. Альманах клинической медицины. 2013; 28: 25–31.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Fedulkina V.A., Vatazin A.V., Kil'djushevskij A.V., Stolja- revich E.S., Kantarija R.O., Zul'karnaev A.B. Translati- onal cellular immunotherapy in urological patients after cadaveric kidney allograft. Al'manah klinicheskoj medi- ciny. 2013; 28: 25–31 (in rus).</mixed-citation><mixed-citation xml:lang="en">Fedulkina V.A., Vatazin A.V., Kil'djushevskij A.V., Stolja- revich E.S., Kantarija R.O., Zul'karnaev A.B. Translati- onal cellular immunotherapy in urological patients after cadaveric kidney allograft. Al'manah klinicheskoj medi- ciny. 2013; 28: 25–31 (in rus).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
