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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vtio</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник трансплантологии и искусственных органов</journal-title><trans-title-group xml:lang="en"><trans-title>Russian Journal of Transplantology and Artificial Organs</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-1191</issn><publisher><publisher-name>Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15825/1995-1191-2016-3-128-136</article-id><article-id custom-type="elpub" pub-id-type="custom">vtio-679</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзор литературы</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Literature Reviews</subject></subj-group></article-categories><title-group><article-title>ДЛИТЕЛЬНАЯ МЕХАНИЧЕСКАЯ ПОДДЕРЖКА КРОВООБРАЩЕНИЯ КАК АЛЬТЕРНАТИВА ТРАНСПЛАНТАЦИИ СЕРДЦА</article-title><trans-title-group xml:lang="en"><trans-title>DURABLE MECHANICAL CIRCULATION SUPPORT AS AN ALTERNATIVE TO HEART TRANSPLANTATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Готье</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gautier</surname><given-names>S. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иткин</surname><given-names>Г. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Itkin</surname><given-names>G. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>123182, г. Москва, ул. Щукинская, д. 1. Тел. (499) 190-60-34</p></bio><bio xml:lang="en"><p>1, Shchukinskaya st., Moscow, 123182, Russian Federation. Tel. (499) 190-60-34</p></bio><email xlink:type="simple">georgeitkin@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шевченко</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Shevchenko</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра кардиологии</p></bio><bio xml:lang="en"><p>Department of cardiology</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Халилулин</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Khalilulin</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра трансплантологии и искусственных органов</p></bio><bio xml:lang="en"><p>Department of transplantology and artifi cial organs</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlov</surname><given-names>V. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России, Москва; &#13;
Московский физико-технический институт (государственный университет), кафедра физики живых систем, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow; &#13;
Moscow Institute of Physics and Technology (State University), Department of physics of living systems, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБУ «Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова» Минздрава России, Москва; &#13;
ГБОУ ВПО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Минздрава России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs of the Ministry of Healthcare of the Russian Federation, Moscow; &#13;
N.I. Pirogov First Moscow State Medical University, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Московский физико-технический институт (государственный университет), кафедра физики живых систем, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Institute of Physics and Technology (State University), Department of physics of living systems, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>18</day><month>11</month><year>2016</year></pub-date><volume>18</volume><issue>3</issue><fpage>128</fpage><lpage>136</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Готье С.В., Иткин Г.П., Шевченко А.О., Халилулин Т.А., Козлов В.А., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Готье С.В., Иткин Г.П., Шевченко А.О., Халилулин Т.А., Козлов В.А.</copyright-holder><copyright-holder xml:lang="en">Gautier S.V., Itkin G.P., Shevchenko A.O., Khalilulin T.A., Kozlov V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.transpl.ru/vtio/article/view/679">https://journal.transpl.ru/vtio/article/view/679</self-uri><abstract><p>В обзоре проведен сравнительный анализ лечения терминальной хронической сердечной недостаточности с помощью трансплантации сердца и длительной механической поддержки кровообращения. Показаны основные преимущества и ограничения трансплантации сердца и перспективы применения технологии длительной механической поддержки кровообращения. Рассмотрены основные направления данной технологии, включая двухэтапную трансплантацию сердца (bridge to transplant – BTT), восстановления миокарда на фоне работы вспомогательного насоса (bridge to recovery – BTR) и имплантация вспомогательного насоса на постоянной основе (destination therapy – DT). </p></abstract><trans-abstract xml:lang="en"><p>In the review a comparative analysis of the treatment of end-stage chronic heart failure using heart transplantation and durable mechanical circulatory is conducted. It shows the main advantages and limitations of heart transplantation and the prospects of application of durable mechanical circulatory support technology. The main directions of this technology, including two-stage heart transplant (bridge to transplant – BTT), assisted circulation for myocardial recovery (bridge to recovery – BTR) and implantation of an auxiliary pump on a regular basis (destination therapy, DT). </p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая сердечная недостаточность</kwd><kwd>трансплантация сердца</kwd><kwd>механическая поддержка кровообращения</kwd><kwd>восстановление миокарда</kwd><kwd>насосы пульсирующего потока</kwd><kwd>насосы непульсирующего потока</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic heart failure</kwd><kwd>heart transplantation</kwd><kwd>mechanical circulatory support</kwd><kwd>myocardial recovery</kwd><kwd>pulsatile flow pumps</kwd><kwd>non-pulsatile pumps</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Готье СВ, Хомяков СМ. 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