References

vtio

Вестник трансплантологии и искусственных органов

Russian Journal of Transplantology and Artificial Organs

1995-1191

Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation

10.15825/1995-1191-2016-2-152-162

vtio-650

Research Article

Обзор литературы

Literature Reviews

ТРАНСДЕРМАЛЬНЫЙ ПЕРЕНОС ЛЕКАРСТВЕННЫХ ВЕЩЕСТВ И СПОСОБЫ ЕГО УСИЛЕНИЯ

TRANSDERMAL DRUG DELIVERY AND METHODS TO ENHANCE IT

Кузнецова

Е. Г.

Kuznetsova

E. G.

Лаборатория тканевой инженерии и систем доставки отдела биомедицинских технологий и тканевой инженерии.

Для корреспонденции: Кузнецова Евгения Геннадьевна. Адрес:123182, г. Москва, ул. Щукинская, д. 1. Тел. (499) 193-86-62. E-mail: kuzeugenia@gmail.com.

Laboratory of tissue engineering and delivery systems of department of biomedical technologies and tissue engineering.

For correspondence: Kuznetsova Evgeniya Gennadievna. Address: 1, Shchukinskaya Str., Moscow, 123182, Russian Federation. Тel. (499) 193-86-62. E-mail: kuzeugenia@gmail.com

kuzeugenia@gmail.com

Рыжикова

В. А.

Ryzhikova

V. A.

Лаборатория тканевой инженерии и систем доставки отдела биомедицинских технологий и тканевой инженерии

Laboratory of tissue engineering and delivery systems of department of biomedical technologies and tissue engineering

Саломатина

Л. А.

Salomatina

L. A.

Лаборатория тканевой инженерии и систем доставки отдела биомедицинских технологий и тканевой инженерии

Laboratory of tissue engineering and delivery systems of department of biomedical technologies and tissue engineering

Севастьянов

В. И.

Sevastianov

V. I.

Лаборатория тканевой инженерии и систем доставки отдела биомедицинских технологий и тканевой инженерии

Laboratory of tissue engineering and delivery systems of department of biomedical technologies and tissue engineering

Федеральный научный центр трансплантологии и искусственных органов имени академика В.И. Шумакова, МоскваРоссияV.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowRussian Federation

2016

26062016

182152162

2016

Кузнецова Е.Г., Рыжикова В.А., Саломатина Л.А., Севастьянов В.И.

Kuznetsova E.G., Ryzhikova V.A., Salomatina L.A., Sevastianov V.I.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://journal.transpl.ru/vtio/article/view/650

В статье представлены общие подходы, применяемые в последнее время для усиления чрескожного переноса лекарственных субстанций при аппликации трансдермальных терапевтических систем. Подробно рассмотрены химические, физические и механические способы усиления транспорта высокомолекулярных соединений через кожу.

The paper presents the common methods employed in recent years for enhancing transdermal delivery of drug substances when applying transdermal therapeutic delivery systems. The chemical, physical and mechanical methods to enhance the transport of macromolecular compounds through the skin are considered in details.

трансдермальный перенострансдермальная терапевтическая системаактиватор переносаионофорезсонофорезэлектропорацияхолодная плазма

transdermal deliverytransdermal drug delivery systemtransfer activatoriontophoresissonophoresiselectroporationcold plasma

Министерство здравоохранения Российской Федерации

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The authors declare that there are no conflicts of interest present.