vtioВестник трансплантологии и искусственных органовRussian Journal of Transplantology and Artificial Organs1995-1191Academician V.I.Shumakov National Medical Research Center of Transplantology and Artificial Organs", Ministry of Health of the Russian Federation10.15825/1995-1191-2011-3-82-86vtio-420Research ArticleОбзор литературыLiterature ReviewsПРИМЕНЕНИЕ ВСПОМОГАТЕЛЬНЫХ НАСОСОВ ДЛЯ ВОССТАНОВЛЕНИЯ ФУНКЦИИ МИОКАРДА У ПАЦИЕНТОВ С ХРОНИЧЕСКОЙ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТЬЮTHE USE OF VENTRICLE ASSIST DEVICES TO RESTORE MYOCARDIAL FUNCTION IN PATIENTS WITH CHRONIC HEART FAILUREИткинГ. П.ItkinG. P.georgeitkin@mail.ruТрухмановС. Б.TrukhmanovS. B.ШемакинС. Ю.ShemakinS. Yu.ПопцовВ. Н.PoptsovV. N.ШумаковД. В.ShumakovD. V.ГотьеС. В.GautierS. V.ФГУ «Федеральный научный центр трансплантологии и искусственных органов им. академика В.И. Шумакова» Минздравсоцразвития РФ, МоскваРоссияAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowRussian Federation201120062014133ВЕСТНИК ТРАНСПЛАНТОЛОГИИ И ИСКУССТВЕННЫХ ОРГАНОВ том XIII No 3–20118286Copyright © Иткин Г.П., Трухманов С.Б., Шемакин С.Ю., Попцов В.Н., Шумаков Д.В., Готье С.В., 20112011Иткин Г.П., Трухманов С.Б., Шемакин С.Ю., Попцов В.Н., Шумаков Д.В., Готье С.В.Itkin G.P., Trukhmanov S.B., Shemakin S.Y., Poptsov V.N., Shumakov D.V., Gautier S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.transpl.ru/vtio/article/view/420

В обзоре представлены данные о результатах восстановления функции миокарда у пациентов с терми- нальной стадией хронической сердечной недостаточности (ХСН) при длительном применении систем вспомогательного кровообращения. Наиболее эффективные методы лечения хронической сердечной недостаточности получены при сочетанном применении левожелудочкового обхода и медикаментозной терапии, направленных на нормализацию клеточных, структурных и функциональных характеристик миокарда («обратное ремоделирование»). Важным этапом восстановления миокарда до эксплантации насосов является создание условий для «физиологической гипертрофии» сердца. Применение данных методик открывает путь к лечению больных с дилатационной кардиомиопатией, альтернативный транс- плантации сердца. 

The review presents the data on the results of recovery the myocardial function in patients with end-stage chro- nic heart failure and prolonged using of the systems assist device. The most effective treatment of the chronic heart failure was received by the combination of the left ventricular bypass and the medical therapy aimed at normalizing the cellular, structural and functional characteristics of the myocardium («reverse remodeling»). An important step in restoring the myocardium to explantation pump is to create the conditions for the «physiologic hypertrophy» of the heart. The application of this technology will open the way for the treatment of patients with dilated cardiomyopathy, alternative heart transplantation. 

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The authors declare that there are no conflicts of interest present.